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Doctor insights on: Why Is Nephrin And Proteinuria Relevant At All To Diabetes

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Why is nephrin and proteinuria relevant at all to diabetes?

Why is nephrin and proteinuria relevant at all to diabetes?

Stops protein loss: Nephrin is a protein on the kidney and helps prevent protein loss in the kidney. Proteinuria is when the kidney spills excessive amounts of protein in the urine. Diabetes can damage the kidney and cause the kidney to spill excessive protein thus leading to severe kidney disease. Nephrin is important because it helps prevent excessive protein leak from occurring. ...Read more

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Dr. Quang Nguyen
3,207 doctors shared insights

Diabetes (Definition)

Diabetes is a disease of increased blood glucose levels. Glucose is a type of sugar that comes from the intake of food. Insulin is a type of hormone that removes the glucose from the blood and moves it into the cells to provide them with energy. There are two different types of diabetes: type 1 and type 2. Type 1 diabetes is when the body does not make any insulin. Therefore, glucose stays inside the blood and does not move into the cells. Type 2 diabetes, which is commonly associated with obesity, is when the body is either resistant to the effects of insulin or when the body does not produce enough insulin. Increased levels of glucose in the body causes severe damage to the ...Read more


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How do ACE inhibitors reduce proteinuria with regard to nephrin levels?

How do ACE inhibitors reduce proteinuria with regard to nephrin levels?

Proteinuria and ACE: Ace-inhibtors reduced proteinuria (p) by reducing the vasoconstriction caused by angiotensin ii on the efferent arteriole (ea) of the glomerulus. Once this pressure is reduced, there is less back pressure in the glomerulus, thereby reducing the amount of p the patient has. Other agents, such as angiotensin receptor blockers can also do the same thing. ...Read more

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Could you tell me what happens when you have proteinuria and type one diabetes?

Could you tell me what happens when you have proteinuria and type one diabetes?

Proteinuria: Proteinuria (p) is an ominous sign in both diabetic and non-diabetic patients. You need to see a nephrologist (n) and have a 24 hour urine collection done for a creatinine clearance and protein. Once the results are back, a treatment plan can start. Patients with p have a higher incidence of stroke, kidney failure and heart attacks related to the severity of their p. See a n for meds to reduce p. ...Read more

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Type 1 diabetes and proteinuria is it ok to live a normal life with these two things? Im am so worried for my 13yrdaughter who recently was diagnosis w this

Type 1 diabetes and proteinuria is it ok to live a normal life with these two things? Im am so worried for my 13yrdaughter who recently was diagnosis w this

Prognostic finding: 40% of type 1 diabetics and 10% of type 2 diabetics go on to have renal dysfunction. The early marker for both is the presence of proteiinuria. The rate of decline, and importance of glucose control are still within your control. Your physician can advise on strategies to preserve renal function like acei inhibitors or a2rb's. ...Read more

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Severe edema from waist down, worsening daily, caused by proteinuria (+2), does not respond to diuretics, no HBP, no diabetes, kideny,heart ok.Cause?

Severe edema from waist down, worsening daily, caused by proteinuria (+2), does not respond to diuretics, no HBP, no diabetes, kideny,heart ok.Cause?

IVC occlusion: Whoa. +2 proteinuria does not cause massive edema of your lower body. I suspect you have occlusion of your inferior vena cava by a thrombus perhaps propagated from a renal vein, or occlusion by somthing, perhaps tumor in or around it. Get with a consultant physician who's a good communicator. ...Read more

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Is it normal to have protein in urine while pregnant with diabetes?

Is it normal to have protein in urine while pregnant with diabetes?

Depends: Protein in the urine is never normal but it is often seen in pregnant women with diabetes. Diabetes is a systemic disease that affects many of the body systems including the renal system (kidneys). Depending on how bad your diabetes is, you can experience some protein leakage in the urine. ...Read more

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I have type 2 diabetes and have prptien in my urine and have been put on a high blood pressure medication for this. What does protein in urine mean?

I have type 2 diabetes and have prptien in my urine and have been put on a high blood pressure medication for this.  What does protein in urine mean?

Kidney Damage: Presence of protein in urine is a sign of kidney damage caused by diabetes. It is called diabetic nephropathy. The higher the protein level in urine the worse the damage. Protein level less than 300 mg can be managed by your primary care physician. Higher levels usually require care of a nephrologist. ...Read more

Dr. Nour Baltagi
119 doctors shared insights

Proteinuria (Definition)

Proteinuria means the presence of excess of serum proteins in the urine. The excess protein in the urine often causes the urine to become foamy. Up to 150 mg a day of protein may be excreted by a normal person most of this being tamm-horsfall protein. Between 150-300 mg/day may be considered microalbuminuria and greater than 300mg/day is abnormal and ...Read more


Dr. Linda Callaghan
98 doctors shared insights

Protein In Urine (Definition)

Protein is an expensive commodity for the body. The kidneys are entrusted to return protein back to the body during filtering, and not lose it to the urine. Losses > 150mg/day are indicative of a problem with the filtration mechanism of the kidney. A nephrologist should be consulted ...Read more