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Doctor insights on: Why Is Cystic Fibrosis More Common In Caucasians

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What are the common symptoms of having cystic fibrosis?

What are the common symptoms of having cystic fibrosis?

Cough + sputum: If above applies, kiss him/her on the skin. If you taste salt it might be cf. A simple sweat test will rule it in or out. ...Read more

Caucasian (Definition)

Caucasian, to most people, means a white person. But by the racial classification made in the 19th century, it ranged from people with light skin (no. Europe) to darker (parts of no. Africa & india). These people were felt to be originally from the caucases region of southeastern europe. At it's current core meaning, it is a white person, or ...Read more


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Is there a common age to start showing signs of cystic fibrosis?

Is there a common age to start showing signs of cystic fibrosis?

Birth to teen years: The most common variant of CF is detected at birth or would appear shortly thereafter anyway. Most cases are caught by the teen years, but rarer forms show up as late as 30 or so. ...Read more

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Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

Not true: Cystic fibrosis is a metabolic disorder more common in caucasions by present in many populations. The incidence is 1/3500 caucasion, 1/17, 000 african american, 1/80, 000 native american. It arises in mutations in the cftr gene that regulates cellular transport of chloride. There are in excess of 700 known mutations recorded but most common is the delta 508. ...Read more

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If no one in my family has cystic fibrosis like even my distant relatives and my dad is arabic and my mom is caucasian can I stil hav cystic fibrosis?

If no one in my family has cystic fibrosis like even my distant relatives and my dad is arabic and my mom is caucasian can I stil hav cystic fibrosis?

At your age very unl: Ikely. At birth in most if not all states a tiny blood sample is taken and analyzed for a number of inborn errors of metabolism including the gene which controls the transport of the chloride ion across your cell membranes which is the underlying defect in CF. Problems almost always show up very early and are usually checked with an iontopheresis test. ...Read more

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During my preconception visit my dr. Was really pushing genetic screening for before we start conceiving. We have no family history of genetic disorders and she said nothing stands out (other than cystic fibrosis since we are both Caucasian).?

During my preconception visit my dr. Was really pushing genetic screening for before we start conceiving. We have no family history of genetic disorders and she said nothing stands out (other than cystic fibrosis since we are both Caucasian).?

See below: In addition to screening for cystic fibrosis, Indications for screening include, AMONG OTHERS, any one of the following:**A known or suspected hereditary disease in the patient or a family member; **Presence of birth defects, chromosomal abnormality, intellectual disability, developmental delay in a parent, a child, or the child of a family member**Ashkenazi Jewish ethnicity ...Read more

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How can cystic fibrosis affect p.I.E.S development?

How can cystic fibrosis affect p.I.E.S development?

Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US. A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications. Emotional & phys. Development depend on severity, time in hospital, complications. Morb. & mort. Factors afect emotional, cognitive behavior. ...Read more

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Can someone be diagnose with cystic fibrosis in their 40's?

Can someone be diagnose with cystic fibrosis in their 40's?

As a carrier: Genetic carrier testing:
more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more

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I have symptoms of cystic fibrosis. Is it possible to start show the symptoms in my 30's?

Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read more

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I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

Yes: However, usually an adult who is diagnosed so late has usually had chronic problems with cough and "pneumonias". That said I've diagnosed a new case in a 38 year old woman. ...Read more

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What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

Overall 1/3700: Acording to the CF foundation: the overall birth prevalence is 1/3700. It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000.
More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more

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What is cystic fibrosis?

Genetic disorder: It is a genetic disorder characterized by abnormal sodium channels, which affect a great deal of problems including the respiratory and digestive systems. It is most commonly diagnosed in infants failing to gain appropriate weight, and in children who have multiple chronic infections. ...Read more

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Can you die of cystic fibrosis?

Yes but: Yes but with early diagnosis and regular care and adherence to prescribed therapy by a pediatric pulmonologist the long term survival has improved greatly in the past two decades. ...Read more

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What is cystic fibrosis exactly?

Inherited disease: Cystic fibrosis (CF) is an inherited disease that affects the cells lining the lungs, sinuses, intestines, spleen and liver. It prevents chloride ions from crossing the cell membranes properly. This can clog organ ducts. In the lungs, the extra mucus crushes the cilia and leads to more lung infections. Medications can help; in late-stage disease, lung transplantation may be life-saving. ...Read more

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What is risk of cystic fibrosis?

Depends on genes: The risk of acquiring cystic fibrosis (CF) depends on whether the parents of a child are carriers for the gene. It is estimated that about 1 in 20 americans are carriers of the CF gene. In order for a child to acquire the disease, both parents must be carriers. If both parents are carriers, there is then a 25% chance that the child will acquire the disease. ...Read more

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What exactly is cystic fibrosis?

Cystic fibrosis: CF is a genetic disease that from birth causes the body to produce a thick and sticky mucus. This mucus interferes with the ability to breath and digest food. It is life threatening, but with good management people can live into their 40s and beyond with it. ...Read more

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Can you die from cystic fibrosis?

Yes.: Although the complications of cystic fibrosis are treatable, and although the available treatments are helpful, the disorder shortens the normal life expectancy. ...Read more

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Cystic fibrosis, is it sexlinked?

Autosomal recessive.: Cystic fibrosis (CF) is not sex-linked, but autosomal recessive. That means both parents can be silent carriers--totally unaware--then each passes down this recessive (inactive) gene to their child. This child develops CF because both copies of the formerly inactive gene (1 from each parent) now have no genetic "brake" (normal dominant gene) to prevent the CF gene from expressing itself. ...Read more

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What are symptoms of cystic fibrosis?

Cough, poor growth: Common symptoms of cystic fibrosis include cough, wheeze, recurrent lung infections, poor growth, foul smelling stools, salty sweat, clubbing, and rectal prolapse. The more symptoms the greater the chance of having cystic fibrosis. Most infants today are diagnosed by newborn screening for CF before they develop any symptoms and early therapy can minimize disease symptoms. ...Read more

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How to tell if I have cystic fibrosis?

Sweat test: The gold standard to diagnose cystic fibrosis is the sweat test, which measures the amount of chloride in the sweat. The test takes a few minutes to an hour and is painless. It is done in specialized clinics and hospitals. ...Read more

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Conditions that mimic cystic fibrosis?

The list goes on: There are a whole variety of illnesses that can mimic CF from chronic cough, asthma, to immunodeficiency, broncho pulmonary dysphasia celiac disease, Alpha 1-anti trypsin deficiency. ...Read more

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What is the severity of cystic fibrosis?

What is the severity of cystic fibrosis?

Variable: This depends on the individual patient. There are several hundred CF mutations that have varying degrees of severity. The most common mutation, df508, can cause failure to thrive in infants, recurrent and very serious lung infections during childhood and often pancreatic insufficiency in children. While early diagnosis and preventive treatment have improved, CF is still a fatal disease. ...Read more

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What kind of disease is cystic fibrosis?

What kind of disease is cystic fibrosis?

Genetic: It's a genetic disease that primarily effects the lungs. Here is a great site to learn about cystic fibrosis: http://www. Cff. Org/ ...Read more

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How can I know if I have cystic fibrosis?

How can I know if I have cystic fibrosis?

Get tested: Testing for cystic fibrosis starts with a sweat test. If that is abnormal, genetic testing in the blood is used to confirm the diagnosis by finding the specific genetic mutations. In general, people with CF have recurrent pulmonary infections and abdominal discomfort/diarrhea due to fat malabsorption. ...Read more

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What is cystic fibrosis in children from?

What is cystic fibrosis in children from?

Recessive gene: A mutation is carried in the dna of both unaffected parents & that matching or similar mutation is paired up at conception when the sperm & egg form completed chromasomes with the defective info. Late in pregnancy and after delivery, the effect of the CF gene abnormality begins to reveal itself. In carriers, the good gene compensates for the bad & no problems occur. ...Read more

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Hi what is the cause of cystic fibrosis?

Recessive genes: A mutation is carried in the dna of both unaffected parents ; that matching or similar mutation is paired up at conception when the sperm ; egg form completed chromasomes with the defective info. Late in pregnancy and after delivery, the effect of the CF gene abnormality begins to reveal itself. In carriers, the good gene compensates for the bad ; no problems occur. ...Read more

Dr. William Walsh
992 Doctors shared insights

Cystic Fibrosis (Definition)

A genetic disorder of the lungs and digestive tract. It causes recurrent lung infections and inhibits growth in patients and average life expectancy of patients with cystic fibrosis ...Read more