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Doctor insights on: Why Does The Skin React To Iv Ig

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Why does the skin react to ivig?

Why does the skin react to ivig?

IVIg reactiions: There are many possible explanations for irritation at the site of ivig infusion in the skin. Many experts feel that this may come from aggregation of immunoglobulin molecules that are capable of activating the blood proteins called "complement". Other times, skin reactions may occur as an allergic reaction to a component of the ivig. ...Read more

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Dr. Debra Rosenblatt
18 doctors shared insights

Intravenous Immunoglobulin (Definition)

Intravenous immunoglobulin (IVIG) is a way to provide antibodies to children with documented immune deficiencies and to treat other problems involving the immune system, such as Kawasaki disease. It has also been suggested as a treatment for children with autism spectrum disorders based on the idea that fetal brain development is related to the prenatal immune response, but there is little data ...Read more


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I have small fiber neuropathy with possible ischemic neuropathy. They believe its an autoimmune response. Detected by skin bx. Is this fatal . ? Ivig

I have small fiber neuropathy with possible ischemic neuropathy. They believe its an autoimmune response. Detected by skin bx. Is this fatal . ? Ivig

Not usually: Neuropathy can be painful but usually isn't fatal. It can cause many other issues like wounds that don't heal. These issues can be fatal if not given proper attention. Discuss your fears with your doctor so they can guide you better. ...Read more

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I was dx'd with small fiber autonomic polyneuropathy with microvascular injury syndrome on skin biopsy. What are treatments and prognosis will ivig he?

I was dx'd with small fiber autonomic polyneuropathy with microvascular injury syndrome on skin biopsy. What are treatments and prognosis will ivig he?

SOMEWHAT UNCLEAR: Not fully clear as to how a skin punch biopsy can lead to your diagnoses, as all that is usually seen is the number and density of your small fibres. Vascular problems are tough to see on the biopsy, and the fibres involve temperature and pain sensations, not autonomic functions. Would highly recommend a second opinion from a medical school specialist to clarify this. ...Read more

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How commonly is ivig therapy given?

How commonly is ivig therapy given?

Depends: Ivig is a blood product that is given to patients with immunodeficiencies and other diseases. In allergy, ivig is primarily given for those with immune systems that are deficient. Typically the ivig is given monthly. ...Read more

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What is included in an ivig infusion?

What is included in an ivig infusion?

IgG antibodies: Intravenous immunoglobulin (ivig) is a collection of IgG antibodies pooled from the plasma of over 1000 blood donors. Extensive processing to remove other antibodies and possible contaminants makes ivig expensive. The solution that the antibodies are dissolved in sometimes is high in sugar & should be given carefully to diabetics. Most brands also have preservatives in the product. ...Read more

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What is a ivig an is it safe ?

What is a ivig an is it safe ?

IVIG: Ivig stands for intravenous immunoglobulin. This is antibodies pooled from >1000 human blood donors that contains protective antibodies to many virus and bacteria. Even though it is pooled from humans, it is screened for viruses like HIV and hepatitis so this risk is very low. It is common to have mild infusion reactions, but these can be reduced with medication. ...Read more

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I had aidp 40 days before and i was given ivig and recovered a lot but please suggest me how much time will take me to cure completely?

I had aidp 40 days before and i was given ivig and recovered a lot but please suggest me how much time will take me to cure completely?

Difficult to tell: Recovery from aidp is prolonged and not always complete. A rough estimate would be six to nine month to regain motor strength and endurance but it could easily extend to a year. Hopefully you had some rehab as an inpatient and continue as an outpatient, as this on-going therapy is important in focusing the exercise program to your needs. If your not in therapy ask your doctor to refer you. ...Read more

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I had aidp 40 days before and i was given ivig and i recovered a lot but please suggest me how much time will take me to cure completely?

Variable: The myelin coverings of a nerve take about 4 weeks once healing starts, but the axon inside may recover at about .1 mm daily. Yet, some delayed recovery may be due to a relapse or setback, and some pts do have a more chronic course, cidp, which requires more constant ivig. If indeed you had guillain-barre, and EMG can predict outcomes based on findings. ...Read more

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I have been given ivig for aidp problem but i'm recovering at slow rate and i want recover as quickly as possible so what should I do plz suggest ?

Talk to your doctor.: There is no magic cure for this complicated disease. You are already under the care of a professional and your specifics should be discussed with them. ...Read more

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What are ivig treatments and why do I have to be admitted to get them?

What are ivig treatments and why do I have to be admitted to get them?

IgG replace options : Gammaglobulin therapy is primarily used for various congenital or acquired defects involving the humeral or antibody immune system. The therapy replaces deficient or poorly functioning immunoglobulin g. It is also used as an immune modulated in other diseases. It used to be only iv, but now is available for subcutaneous self home infusion. Route often depends on health insurance. Checkit. ...Read more

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