Doctor insights on:
Why Does Glycosuria Occur In Nephritic Syndrome
Different physiology: The blood vessels in the glomeruli are damaged by inflammation in the nephritic syndrome sufficient for at least a few of them to bleed. They merely leak protein in the nephrotic syndrome, in which obvious inflammation in the classic sense is not visible but protein-retaining molecules in the gbm are lost. Famously, the membranoproliferative glomerulonephritis family produces both syndromes. ...Read more
What is the likelihood that glycosuria would occur in the absence of diabetes? Will glycosuria cause kidney damage? Would a UTI cause glycosuria?
A small minority: of people will have slight glycosuria, either normally or due to a genetic kidney disorder. It doesn't generally cause damage to the kidney; elevated glucose, however, will damage the kidney and many other organs. Discuss w/your doctor. Glycosuria can increase potential for uti, not the other way around unless your blood sugar increases. ...Read moreSee 2 more doctor answers
Multiple causes: It is not clear exactly what the cause is (higher rates of uninsured, poorer/overburdened hospitals in the areas that serve them, indifference or racism by physicians/hospital staff, poorer self care and more reluctance to use the healthcare system, poorer overall health). Its likely that all of those play a role. ...Read moreSee 1 more doctor answer
Why are proximal tubular cells not affected in chronic renal failure and thereby not causing glucosuria?
Good question: Chronic renal disease is most often caused by damage to the blood vessels or the glomeruli / filters, leaving the proximal tubular cells able to work on however much filtrate is present. ...Read more
Why is there selective proteinuria in nephritic and nonselective proteinuria in nephrotic syndrome?
Whoa: Who's your instructor? In nephrotic syndrome, the proteinuria may be selective (mostly albumin, as in most cases of minimal changed disease and any other cause of proteinuria in which the gbm is only modestly damaged) or nonselective (lots of globulin also, as see in the more severe nephrotic syndromes). ...Read more
Ideas: If your nephrotic syndrome is due to diabetes, as it sometimes is, this is your answer. If you are being treated for nephrotic syndrome with a glucocorticoid that impairs glucose tolerance, this can explain it. If your kidneys are beginning to fail, there may be some mild glucose intolerance. Only your physician can sort this out. Good luck. ...Read more
Why is the urine of patients with diabetes mellitus bright (almost neon) yellow? Also, what causes the pH spike with diabetes insipidus?
Dehydration, fillers: Bright urine most often comes from dehydration (too little fluid or excess loss of fluids), often seen in diabetes. It can also come from the fillers and buffers in pills, including vitamins. pH spiking is alkalosis or excessively alkaline state from abnormal fluid and electrolyte dynamics. See your PCP or Endocrinologist for electrolyte lab work, and more info and discussion. ...Read more
How often does High blood pressure (hypertension) occur in people with Alcohol withdrawal syndrome?
Very common in AWS: Alcohol withdrawal (AWS) is hyperadrenergic state. In it, a lot of adrenaline & other chemicals run around that wouldn't otherwise be released. High Blood Pressure (requiring clonidine & other medication) is VERY common & part of the "AWS treatment package" in many medical centers. Clonidine also stabilizes the heart rate, which can be increased. TTYD or use HealthTap Prime if you experience AWS. ...Read more
Possibly: Sjogrens syndrome will typically presenst with dry eyes and dry mouth. It is not uncommon for sjogrens to occur with other rheumatic illnesses such as lupus. We call this secondary sjogrens and tends to cause the above issues. We still treat the underlying illness and in your case lupus. Sjogrens can occur by itself and we call this primary sjogrens and may have more issues then secondary sjogrens. ...Read more
Only late: Patients with chronic kidney disease usually do well for years with no symptoms. This depends on the cause of the kidney problem. It is important for close follow up by your doctor or nephrologist to minimize further kidney damage. The actual changes in the kidney depend on the causre, but the ultimate effect is gradual reduction of the kidney's ability to clear waste products from blood. ...Read more
See below: Nephrotic syndrome can be caused by many diseases . Diseases such as diabetic nephropathy, membranous gn, fsgs may cause nephrotic syndrome hematuria and proteinuria occur in eg lupus nephritis the prescence of only proteinuria helps the clinician narrow down to certain diseases before resorting to a biopsy. ...Read moreSee 1 more doctor answer
CAH: Most common is 21 hydroxylase deficiency. Females born with it usually have ambiguous genitalia because a block in adrenal hormone synthesis causes an androgen buildup. Can't tell by looking at a boy. State newborn screening should pick it up right away. Medical emergency to identify as medication is necessary to replace cortisol and aldosterone within a couple of days after birth else crisis. ...Read moreSee 1 more doctor answer
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