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Doctor insights on: Why Do We Give Antiestrogen Drugs To Those Who Have Breast Cancer

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Dr. Barry Rosen
4,348 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Why do we give antiestrogen drugs to women who have breast cancer ?

Why do we give antiestrogen drugs to women who have breast cancer ?

To slow growth: Most breast cancers are stimulated by estrogen and progesterone, the normal female sex hormones. When deprived of these hormones, the tumors often die. Consequently, breast cancer tumors are tested to find out if they are sensitive to these hormones. If so, medicines to block these hormones are given as part of the cancer treatment for breast cancer. ...Read more

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Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?

Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?

Anti-estrogen drugs: Anti-estrogen drugs are given to both premenopausal and postmenopausal women whose cancer is estrogen receptor-positive or progesterone receptor-positive. These cancer may grow when exposed to estrogen. Anti-estrogen medications block or reduce estrogen that is normally produced by the ovaries in premenopausal women or by fat cells, liver, adrenal glands or other organs in postmenopausal women. ...Read more

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What is the reason we give antiestrogen drugs to post-menopausal women who have breast cancer ?

What is the reason we give antiestrogen drugs to post-menopausal women who have breast cancer ?

Astute question!!: Post menopausal women and women who had their ovaries removed still produce sex steroids in the adrenal glands that are later converted to estrogen. Cancer cells learn how to function with those minute quantities of Estrogens and for that reason we target the estrogen receptor pathway in these women. Thank you for that good question. ...Read more

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Why do they treat some woman with breast cancer with herceptin (trastuzumab)?

Why do they treat some woman with breast cancer with herceptin (trastuzumab)?

Herceptin (trastuzumab) breast ca: About 1/4 cases of breast cancer express a protein on the surface of the cancer cells called her2neu which is a member of the epidermal growth factor family of receptors important for growth signaling into the cell nucleus. Herceptin (trastuzumab) is an antibody developed to target her2neu and antagonize this growth signaling and kill the cancer cell. Chemo is synergistic with Herceptin (trastuzumab) when given together. ...Read more

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Do doctors put implants in women with family history of breast cancer if they want it?

Do doctors put implants in women with family history of breast cancer if they want it?

Yes, but...: ...Not without the appropriate counseling of the pro's and con's. To wit: implants can interfere with the ability to perform the best test that we have for screening for breat cancer--mammograms. On the other hand, 85-90% of all breast cancers occur due to environmental factors rather than heredity, so many women have less of a family risk than they may realize. ...Read more

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I've read about women with breast cancer in one breast choosing to have both removed.  why would you do that?

I've read about women with breast cancer in one breast choosing to have both removed.  why would you do that?

Several reasons: 1. To avoid getting a second cancer in the healthy breast down the road 2. Because she has a brca1/2 mutation which puts her at higher risk for a second breast cancer 3. To have breast reconstruction done on both breasts at the same time 4. To avoid the anxiety and nuisance of mammograms and biopsies in the future. ...Read more

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What to do if i want to know why some women get blood in thier urine with ovarian cancer?

What to do if i want to know why some women get blood in thier urine with ovarian cancer?

Cancer spread: Unfortunately, ovarian cancer is usually not detected until it has already spread and involved other organs. If it has involved the bladder you will usually see blood in the urine. ...Read more

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Can you let me know how many women in the us are in high rist having breast cancer?

Lots: Any woman of reproductive age and older can get cancer of the breast. The risk varies greatly depending on age, ethnicity, family history, reproductive factors, lifestyle factors (like diet and exercise) and many others. Every person is different so if you have questions about your particular risk, i advise going over it with your doc. There are ways to estimate risk and do something about it. ...Read more

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Can you please list the most common ideas to give to people if they donate to breast cancer research?

Think Pink: There are many reputable organizations out there that raise funds for breast cancer, but the breast cancer research foundation actually contributes about 90% of its funds to research. http://www.bcrfcure.org/ also consider supporting the american cancer society. http://www.cancer.org/. ...Read more

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Why do so many people support breast cancer but not testicular cancer?

Why do so many people support breast cancer but not testicular cancer?

The social context: Breast cancer is more common, there is an industry to subsidize the events and pink ribbons (mammography machine manufacturers), body image is a concern, and there is at least one demographic in which breast cancer carries a superstitious dread. The "activism" is a good thing overall. A sensible man who finds a testicular lump gets with his physician and usually gets a cure. Less fearful overall. ...Read more

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Why are doctors reluctant to prescribe armour or any ndt? It seems that those who do use it feel tremendously better

Why are doctors reluctant to prescribe armour or any ndt?  It seems that those who do use it feel  tremendously better

Different doctors: have different reasons. In general, however, it is harder to titrate the dose. Since it is simply ground up pig thyroid, there is no guarantee how much hormone you will get with each pill (there is variability). Synthroid or levothyroxine is also biochemically identical to human thyroid hormone, pig hormone is not. Patients probably feel better due to the T4/T3 combo. ...Read more

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My mom doesn't want to get surgery so are there any other alternatives to treat breast cancer?

My mom doesn't want to get surgery so are there any other alternatives to treat breast cancer?

Multimodal therapy: Breast cancer treatment is often a combination of surgery, chemotherapy and radiation. It is hard to cure early breast cancer without surgery as part of the treatment. Sometimes they can give chemotherapy before surgery to limit the extent of surgery. ...Read more

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Why do some doctors give chemo before surgery to shrink breast tumor?

Why do some doctors give chemo before surgery to shrink breast tumor?

To shrink big tumors: Neoadjuvant chemotherapy is for three main reasons: 1. To treat inflammatory breast cancer, when chemotherapy should always be given before surgery 2. To shrink large breast cancers that are very close to the chest wall muscle before they have a chance to invade 3. To shrink large tumors in order to avoid a mastectomy and have only the lump removed instead (lumpectomy). The risk of cancer returning is no different that having chemotherapy after surgery. ...Read more

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How do I give moral support to someone with breast cancer?

How do I give moral support to someone with breast cancer?

Be there- for her: Be there to listen not to advise unless asked - men fail at that aspect. Go with her to the doctor's appt. Again to listen and/or to ask questions that your friend expressed to you and forgot - their heads are spinning. With you they will not feel alone. Today i had 3 such patients all by themselves after previously calling them with the diagnosis so that they could ask someone to be there.Thanku. ...Read more

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What can we do to help promote breast cancer awareness?

What can we do to help promote breast cancer awareness?

Breast Cancer: There are several differs ways to provide support and raise awareness for breast cancer. In central texas we have the cancer support community of central texas for psychosocial support. The way i try to raise awareness is let people know that roughly only a third of women who have mastectomies were informed about their options regarding breast reconstruction. There is legislation to help change. ...Read more

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Do people with breast cancer have to get their breasts cut off?

Do people with breast cancer have to get their breasts cut off?

No: If the cancer is small and found early, then a lumpectomy (just remove tumor) and radiation can be performed.. If the cancer is large, some people can get chemotherapy to shrink the tumor and then get lumpectomy. The earlier the cancer is found, more treatment options are available. It is important to ask questions and even a 2nd opinion can be helpful. ...Read more

Dr. Barry Rosen
1,380 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Dr. Mark Hoepfner
1,063 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more