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Doctor insights on: Why Do We Give Antiestrogen Drugs To Those Who Have Breast Cancer

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Dr. Barry Rosen
1,337 doctors shared insights

Breast Cancer (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


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Why do we give antiestrogen drugs to women who have breast cancer ?

Why do we give antiestrogen drugs to women who have breast cancer ?

To slow growth: Most breast cancers are stimulated by estrogen and progesterone, the normal female sex hormones. When deprived of these hormones, the tumors often die. Consequently, breast cancer tumors are tested to find out if they are sensitive to these hormones. If so, medicines to block these hormones are given as part of the cancer treatment for breast cancer. ...Read more

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What is the reason we give antiestrogen drugs to post-menopausal women who have breast cancer ?

What is the reason we give antiestrogen drugs to post-menopausal women who have breast cancer ?

Astute question!!: Post menopausal women and women who had their ovaries removed still produce sex steroids in the adrenal glands that are later converted to estrogen. Cancer cells learn how to function with those minute quantities of Estrogens and for that reason we target the estrogen receptor pathway in these women. Thank you for that good question. ...Read more

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Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?

Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?

Anti-estrogen drugs: Anti-estrogen drugs are given to both premenopausal and postmenopausal women whose cancer is estrogen receptor-positive or progesterone receptor-positive. These cancer may grow when exposed to estrogen. Anti-estrogen medications block or reduce estrogen that is normally produced by the ovaries in premenopausal women or by fat cells, liver, adrenal glands or other organs in postmenopausal women. ...Read more

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Can you give me suggestions on symptoms of breast cancer?

Can you give me suggestions on symptoms of breast cancer?

Any change in breast: A mass can present deep in the breast or it can be up against the skin causing skin changes. Bloody nipple discharge is also something to investigate. You need to do a monthly self breast exam. Feel for any changes. You know your breasts better than anyone. Any mass consult with your doctor. Starting at age 40 a yearly mammogram is recommended. See your doctor at least once a year. ...Read more

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Is there anyone offering to give free breast cancer exams as a regular program, anywhere in the u.S.?

Is there anyone offering to give free breast cancer exams as a regular program, anywhere in the u.S.?

Am Cancer Society: Contact your local american cancer society office. They ususally support free screening mammograms at health fares, and other opportunities. Additionally, your local health department may advise you on free screening locations. ...Read more

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Will soy give you breast cancer?

Will soy give you breast cancer?

No: Since certain soy products have weak estrogenic properties, the claim makes an llogical, scientifically unsupported claim that soy "causes" breast ca. Estrogen itself may promote some breast cancers, and theweaker soys potentially could do this "weakly", . ...Read more

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Will tattoos on breasts give you breast cancer?

Will tattoos on breasts give you breast cancer?

No: For the most part, breast cancers arise from the duct tissues that are responsible for making or secreting milk. Tattoos are usually inert colored inks that are injected just beneath the skin layer and do not get excreted in milk and thus not exposed to ductular tissues. ...Read more

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I want to know what's the new breast cancer drug tdm1?

I want to know what's the new breast cancer drug tdm1?

Salvage Rx: For her2-positive breast cancer that's relapsed. http://www.medscape.com/viewarticle/811845. ...Read more

Dr. Barry Rosen
4,224 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Mark Hoepfner
1,029 doctors shared insights

Breast Carcinoma (Definition)

Breast carcinoma is a type of cancer where this uncontrolled growth of breast cells. Symptoms can include breast lumps, pain, and weight ...Read more