Doctor insights on:
Why Do Some People With Inflammatory Bowel Disease Relapse A Lot
Lots of reasons: Sometimes it is the disease itself. Sometimes, it is the treatment. Including wrong dose, med, inad duration. Some put people into remission, but not maintain it. Sometimes, it is poor compliance with prescribed treatments due to any number of reasons. Sometimes it is cigarette smoking. Sometimes, it is symptoms, but not the inflammation that has acted up. Other reasons as well. ...Read more
The gastrointestinal tract starts at the mouth, travel down the tunnel (esophagus), which connects to the stomach, which then empties into the duodenum, jejunum, and ileum---the three parts of the small intestine (@25 feet). This empties into the colon or large intestine (about 5 feet), which then becomes the sigmoid colon, rectum and out the anus. So, every morsel eaten ...Read more
Anxiety & depression: Inflammatory bowel disease (ibd) is a group of diseases including crohn's disease, ulcerative colitis and other types of colitis. The problem is the treatment and the side effects cause depression and anxiety. There is an association of flare ups of ibd with anxiety and depression. Depressed ibd patients run the risk of decreased treatment adherence. ...Read more
IBD defined: Earlier healthtap answers may help. Briefly ibd is a spectum of inflammatory diseases of GI tract. At one end of the spectrum is ulcerative colitis---a disease confined to the mucosal surface of colon. At the opposite end of the spectrum is crohn's disease--a transmural (full thickness) inflammation of any part of GI tract (from mouth to anus). Both are systemic & increase colon cancer risk. ...Read moreSee 1 more doctor answer
Almost anyone: About 15% of close relatives of crohn's patients carry genes that predispose to this inflammatory bowel disease. Also, ethnic origin and environment (including infectious and antigenic exposure as well as tobacco) play roles in disease emergence and "flaring." keep in mind that ibd can present in young, middle aged, or elderly, and almost anywhere and in any population around the world. ...Read more
Cure for IBD?: Ulcerative colitis involves inflammation of the colonic mucosal surface, so colectomy (removal of the colon) is curative for it. Crohn's disease however is a transmural (full-thickness) inflammation of any part of the GI tract (from mouth to anus). Crohn's is not curable, but it is controllable with medications (see my previous healthtap answer regarding "step up" versus "top down" treatments. ...Read moreSee 1 more doctor answer
Many options: 1. 5-asa medications (sulfasalazine, asacol, (mesalamine) pentasa) may work for mild ulcerative colitis (uc), but not crohn's disease. 2. Steroids work, but are only useful for short course because of side effects. 3. Azathioprine (imuran), 6-mp, Methotrexate are often effective, and reduce the need for steroids. 4. Remicade, Humira are often effective for crohn's, sometimes for uc. 5. Surgery if needed. ...Read moreSee 1 more doctor answer
IBD is systemic: Inflammatory bowel disease runs a spectrum from ulcerative colitis (inflammation of inside lining of colon) to crohn's (full-thickness inflammation that can involve any part of gut from mouth to anus). Almost any organ system can be affected, pregnancies are at risk, & there is a high prevalence of cancer development and need for chronic treatment &/or surgical management. Also, genetic proclivity. ...Read more
Medications: Variety of medications that will try to down regulate the inappropriate immune response found in ibd. Mesalamine (ie 5asa) products are a mainstay for uc and crohn's colitis. Other medications include immunosuppresant agents such as 6mp, immuran as well as biologic agents such as remicdae or humira (adalimumab). Steroids such as Prednisone are used in severe flares, but a not a long term option. ...Read moreSee 2 more doctor answers
Depends: Inflammatory bowel disease generally refers to crohn's disease or ulcerative colitis. Both may give you diarrhea up to 10-20 movements per day, uc usually with blood mixed in, abdominal pain, weight loss, loss of energy and numeropus other associated co morbid conditions. If in doubt see either a colorectal surgeon or GI doctor. ...Read moreSee 2 more doctor answers
Many: Gi anti-inflammatory ( 5-asa, mesalamine), steroids (prednisone, budesonide), immunosuppressants (azathioprine, cyclosporine) and biologics (infliximab) are the most common meds used for ibd. Depends on your symptoms and clinical response, combination treatment is common. You need to work closely with your doctor. ...Read more
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