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Doctor insights on: Why Do Patients With Liver Disorders Have Clotting Problems

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Why do patients with liver disorders have clotting problems?

Why do patients with liver disorders have clotting problems?

Liver stops making: The liver makes lots of proteins, including clotting factors. Liver disease (acute or chronic) that knocks out enough active liver cells causes less protein to be made in general, and clotting factors included.. In addition platelets (blood clotting cells) decrease in liver disease. ...Read more

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Dr. Barbara Lavi
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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I was told hepatitis liver enzymes would be in the 1000's and most other serious liver disorders are in the 100's. What are normal levels?

Why do you ask?: Transaminases (sgot/ast, sgpt/alt) are usually below 40. In acute alcoholic or viral hepatitis, levels may be as low as the 400's with the person obviously sick. However, we draw them to look for smoldering, subtle disease (wilson's, chronic hepatitis, hemochromatosis, drug sensitivity, autoimmunity, nafl) and if your physician wants to work you up, it's your choice -- if missed, they can kill you. ...Read more

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For 57+ F what all blood tests are good enough to rule out early/mid stage kidney & liver disorders ?

For 57+ F what all blood tests are good enough to rule out early/mid stage kidney & liver disorders ?

Basic stuff: Physical exam's good? If your BUN / blood urea nitrogen and creatinine are at or near reference range, urinalysis with sediment exam is normal or only has trace protein, and you can concentrate your urine to 1.020 SG, your kidneys are working okay. Liver disease is screened for using the SGOT/AST, SGPT/ALT, and bilirubin; tests of actual liver function are seldom done as these are good screens. ...Read more

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Why do patients with liver disease commonly develop blood clotting disorders?

Why do patients with liver disease commonly develop blood clotting disorders?

Function: One of the livers primary functions is to produce factors in the blood that promote blood clotting. When the liver starts to fail it can't make these factors which leads to people developing problems with clotting appropriately. ...Read more

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Why do patients that ahve liver diseases commonly develop blood clotting disorders?

Why do patients that ahve liver diseases commonly develop blood clotting disorders?

Clotting factors: Most of the clotting factors are made or processed in the liver, and work together with proteins in the blood and with platelets. Therefore, if you have liver disease, these factors are not produced in sufficient quantity or quality to work correctly. Vitamin k is metabolized in the liver and is used in clotting. ...Read more

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High platelets and longer clotting clotting time? Is that a bad liver problem?

High platelets and longer clotting clotting time?  Is that a bad liver problem?

Probably no.: Liver problem usually decrease platelet count but causes prolonged clotting or bleeding time.Elevated platelets and clotting time could suggest some kind of blood disorder. ...Read more

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What is the best diet for a patient with chronic liver disease?

What is the best diet for a patient with chronic liver disease?

Avoid toxic foods: Avoid sugars, fried foods, vegatable oils like canola & soy, meats that are cured wth nitrates & nitrites, aspartame, splenda, partially hydrogenated vegetable oils, maragarine, soy based products, sweetened beverages like juice & soda, microwaved foods, artificial colors & flavors. All of these products cause damage to the cells, tissues & organs in your body contributing to various diseases. ...Read more

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What is the life expectancy for patients with decompensated liver disease?

Not very good: Without knowing more details it is hard to say but the life expectancy without treatment is likely 6 months to a year. ...Read more

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Advice for patients with end stage liver disease?

Advice for patients with end stage liver disease?

Need a doc: If you have end stage liver disease you need to be under the care of ideally a gastroenterologist with an interest in liver disease. ...Read more

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