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Doctor insights on: Why Do Antibiotics Not Work Well Against Pseudomonas Aeruginosa

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Why do antibiotics not work well against pseudomonas aeruginosa?

Why do antibiotics not work well against pseudomonas aeruginosa?

Various reasons: Pseudomonas is a very common bacteria which has developed many clever ways of resisting different antibiotics. It can destroy the antibiotics with chemicals, pump the antibiotics out of its cell or become 'invisible' to antibiotics by changing the appearance of the bacteria. Pseudomonas can adapt to antibiotics & change during the course of treatment. Serious infections often require an expert. ...Read more

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Dr. John Leander Po
1,117 doctors shared insights

Antibiotic (Definition)

An antibiotic is a medicine that slows, stops, or kills germs. The germs are usually bacteria causing an infection in a person, so the person uses antibiotics to help his body get ...Read more


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Can monobactams work to treat pseudomonas aeruginosa?

Can monobactams work to treat pseudomonas aeruginosa?

Yes: But this depends upon what infection and the sensitivities of the strain of pseudomonas with which the patient is infected. ...Read more

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Can cephalosporins work to treat pseudomonas aeruginosa?

Can cephalosporins work to treat pseudomonas aeruginosa?

Yes some: There are many different cephalosporin antibiotics. Many are not effective against ps. Aer. Those that are active against this organism are Fortaz (ceftazidime) and maxipime(cefepime). ...Read more

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Can quinolones work to treat pseudomonas aeruginosa?

Can quinolones work to treat pseudomonas aeruginosa?

Sometimes: Quinilones in the past were very effective against pseudomonas, however because of their widespread and some might say, excessive use in the hospital and community many strains of pseudomonas are now resistant to these antibiotics. They still retain effectiveness in some cases, and specific testing of the germ grown from the patient (culture results) can determine if this is true in a given case. ...Read more

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My coworker has pseudomonas aeruginosa that has caused a corneal ulcer. Should i be worried of contracting it as well?

My coworker has pseudomonas aeruginosa that has caused a corneal ulcer. Should i be worried of contracting it as well?

No : Assuming your coworker is not rubbing her infected eye and then touching surfaces that you touch prior to touching your eyes, the risk is negligable. The bacteria does not have an airborne transmission mode of spread. ...Read more

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Can polymyxins work to treat pseudomonas aeruginosa?

Can polymyxins work to treat pseudomonas aeruginosa?

Yes: Polymyxins are a very old class of antibiotics. They tend to have kidney and nervous system toxicity, and because they are very old the exact effective doses of these drugsis not well known. Still given problems with bacterial antibiotic resistance, sometimes these agents are used when a highly resistant bacteria is encountered. Colistin the one most often used can be given via inhalation or iv. ...Read more

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Can good hygiene prevent pseudomonas aeruginosa infection?

Can good hygiene prevent pseudomonas aeruginosa infection?

Yes and no: Pseudomonas can be transmitted differently - contact exposure, airborne. Also, it may live on some of us without causing any disease, but when local immunity diminishes, it may start causing a problem. Skin infections caused by pseudomonas mandate usual hygiene measures such as hand washing, using protective wear, disposal of infected materials etc. But not 100% guarantee of protection. ...Read more

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I am immuno-compromised, am I more likely to get pseudomonas aeruginosa?

I am immuno-compromised, am I more likely to get pseudomonas aeruginosa?

Possibly: Ps. Aeruginosa infections are most commonly acquired in the hospital setting. They are very common in cystic fibrosis patients. Some compromise in the host health status underlies most of the serious problems with ps. Aer. Infections. Main host factors that affect risk are low white blood cell count, burn wounds or other disruption of skin or mucosal surfaces. ...Read more

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I have cancer am I more likely to get pseudomonas aeruginosa?

I have cancer am I more likely to get pseudomonas aeruginosa?

Probably not: When you have cancer, your immune system is compromised or lower, and this means you are more susceptible to developing an infection. However, it is not specifically to pseudomonas species per se. But, in general, you need to know the cancer type and what the treatment is, since some treatments (like chemotherapy), also decrease your ability to fight off infections effectively. ...Read more

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