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Doctor insights on: Why Do Antibiotics Not Work Well Against Pseudomonas Aeruginosa

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Why do antibiotics not work well against pseudomonas aeruginosa?

Why do antibiotics not work well against pseudomonas aeruginosa?

Various reasons: Pseudomonas is a very common bacteria which has developed many clever ways of resisting different antibiotics. It can destroy the antibiotics with chemicals, pump the antibiotics out of its cell or become 'invisible' to antibiotics by changing the appearance of the bacteria. Pseudomonas can adapt to antibiotics & change during the course of treatment. Serious infections often require an expert. ...Read more

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Dr. John Leander Po
1,117 doctors shared insights

Antibiotic (Definition)

An antibiotic is a medicine that slows, stops, or kills germs. The germs are usually bacteria causing an infection in a person, so the person uses antibiotics to help his body get ...Read more


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Why does sulfisoxazole not work well with all germs?

Why does sulfisoxazole not work well with all germs?

Sensitivity: Sulfisoxazole does not kill all germs. It is effective with many gram negative and gram positive organisms. Different germs are susceptible to different antimicrobials. ...Read more

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I have prostatitis (bacterial). I am taking an antibiotic course. I want to know how will antibiotics kill bacteria if they hide in prostate tissue?

I have prostatitis (bacterial). I am taking an antibiotic course. I want to know how will antibiotics kill bacteria if they hide in prostate tissue?

Prostatitis meds: Hopefully your doctor considered which antibiotics are able to cross into the prostate since u are right- the prostate has a capsule around it that protects it. Bactrim (sulfamethoxazole and trimethoprim) or trimethoprim/sulfamethoxazole and fluoroquinolones (ciprofloxacin, levofloxacin) are commonly used antibiotics for this indication. Treatment needs to be quite long- hope u get some relief. ...Read more

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When do you become immune to topical antibiotics such as clindamycin and erythromycin for acne?

When do you become immune to topical antibiotics such as clindamycin and erythromycin for acne?

Varies: You MUST NOT use antibiotics -- topical or systemic -- as the sole treatment for acne. They need to be part of a combined treatment with topical benzoyl peroxide, salicylic acid, or a retinoic acid derivative. Do this, and you may be able to manage on a combined regimen. If this fails, consider a systemic tetracycline or isotretinoin. The latter works but isn't for the faint-hearted. ...Read more

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What cleansers are effective for cleaning and sterilizing my cpap mask and tubing to kill MRSA so I won't be colonized again?

What cleansers are effective for cleaning and sterilizing  my cpap mask and tubing to kill MRSA so I won't be colonized again?

Dilute bleach: A 1:10 dilution of bleach bottle is inexpensive and effective. Cleaning solutions other than soap and water may decrease the lifespan of your equipment, so more frequent replacement may be necessary. ...Read more

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Can your body defend itself against bacteria in a cut without antibiotics? I think it's awful to rely on antibiotics so much. So I am using polysporin (bacitracin and polymyxin)

Can your body defend itself against bacteria in a cut without antibiotics? I think it's awful to rely on antibiotics so much. So I am using polysporin (bacitracin and polymyxin)

Yes, of course...: ...the body defends itself against infections in cuts, without antibiotics. Antibiotics have only been available for 75-80 years, but through the ages, most wounds didn't get seriously infected. Even now, antibiotics are not usually used to prevent infection in cuts; the main medical advice is to just keep the wound clean and dry. And FYI, polysporin (bacitracin and polymyxin) is an antibiotic ointment. ...Read more

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Does penicillin kill protozoa. If not, what microorganisms apart from bacteria does it work against?

Penicillin activity: Penicillin only kills bacteria. There are other types of germs -- viruses, fungi, protozoa and infectious proteins. For those, other treatments are involved. Penicillin these days has only a few uses, because of resistance (it's one of the oldest antibiotics still used) and the proliferation of other antibiotics that are in some ways easier to use. Talk to an ID doc or pharmacist to learn more. ...Read more

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What to do if URI is antibioic resistant? Herbs?

What to do if URI is antibioic resistant? Herbs?

Try these: Try taking a high dose of good probiotic (MegaFood, Megaflora Plus) 3-4 caps/day, vitamin D3 10,000 Iu/day, zinc 50 mg/day for 7-10 days while you have an infection Take a lower dose of all these on a maintenance basis if you get frequent URI (they help to prevent URI). Licorice tea also helps reduce congestion. Avoid all milk products. ...Read more

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Why do overuse of antibiotics cause strains of pathogens that are resistant to antibiotics?

Why do overuse of antibiotics cause strains of pathogens that are resistant to antibiotics?

See below: Bacteria reproduce at an alarmingly rapid rate. Due to the high rate, the rate or errors in their genetic material is relatively high as well. If a particular mutation gives rise to resistance to the particular antibiotic the patient is taking then that bacteria has a selective advantages and thus flourishes. ...Read more

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Do antibacterial soaps/disinfectants protect against viruses? Wondering if all this disinfecting is doing much against things like h1n1.

Do antibacterial soaps/disinfectants protect against viruses? Wondering if all this disinfecting is doing much against things like h1n1.

Yes and yes.: Hand hygiene when done is actually quite goo at protecting everyone from infection. Alcohol, chlorhexidine, triclosan, bleach solutions, and iodine based sanitizers work well against viruses. So does plain old soap. Spores of certain bacteria are sometimes a problem. ...Read more

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Aren't antibiotics used for sinus infections or congestion? Why does the doctor not want to prescrib

Aren't antibiotics used for sinus infections or congestion? Why does the doctor not want to prescrib

Usually doesn't help: In fact, the vast majority of adult cases of sinusitis, pharyngitis, upper respiratory congestion, % ear infections do not require antibiotics. They are viral & some are allergic. Certain criteria suggest bacterial infections; e.g. Time course, specific signs, & no response to over-the-counter treatment. Also, flu % colds are caused by viruses only so bacterial antibiotics will not work at all. ...Read more

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Since antibiotics are made to kill bacteria, can I use any antibiotics to fight my mild acne?

Since antibiotics are made to kill bacteria, can I use any antibiotics to fight my mild acne?

This is a common RX: Depending on the type of acne, the use of antibiotic solutions or oral antibiotics are sometimes used as part of treatment. The drawback is the skin germs can become resistant to whatever is being used at the time which leads to treatment failure. Find a skin doc you can work with and come up with a treatment plan you can work with. ...Read more

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Please answer! what makes some bacteria resistant to antibiotics when other bacteria are not?

Please answer! what makes some bacteria resistant to antibiotics when other bacteria are not?

Various reasons: Some bacteria are resistant because they do not have the correct target for the drug to work, others are resistant because they produce an enzyme that inactivates the drug. ...Read more

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If I haven't ever taken antibiotics other than a few necessary times, does that mean antibiotic resistant bacteria won't affect me?

Antibotic resistance: Your use of antibiotics has no effect on antibiotic resistant strains. You have the same risk as everyone else getting an antibiotic resistant bacterial infection ...Read more

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Are there any bacteria that augmentin could work better against in the testicles that cipro (ciprofloxacin) wouldn't work at all or/well against?

Are there any bacteria  that augmentin could work better against in the testicles that cipro (ciprofloxacin) wouldn't work at all or/well against?

Probably neither one: The most common infection involving the testicles is epididymitis. At your age (22) most cases are caused by chlamydia or gonorrhea, and neither ciprofloxacin nor augmentin (amoxicillin and clavulanate) is reliable against either of them. If it's something else, or epididymitis cause by urinary tract infection bacteria, either may work but cipro probably is more reliable than augmentin (amoxicillin and clavulanate). I hope you're under a doctor's care. ...Read more

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How do bacteria develop resistance against the antibiotics we took for years?

How do bacteria develop resistance against the antibiotics we took for years?

Genetics: Bacteria adapt to antibiotics for survival. Small genetic mutations develop that give a bacterium a survival advantage. It makes copies of this genetic anamoly (on a separate genetic fragment called a plasmid) that then is passed on to other bacteria of the same species. Over time, succeeding generations have this advantage and since they survived, they are now resistant. ...Read more