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Doctor insights on: Why Did Mirtazapine Work For Sleep The First Night But Not The 2nd

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Dr. Ihab Ibrahim
382 Doctors shared insights

Mirtazapine (Definition)

Mirtazepine (remeron) is a noradrenergic/specific serotonergic antidepressant [nassa]. It is used for major depressive d/o, various anxiety disorders, chronic pain, and others. In some, it can help ssri-induced sexual dysfunction & "poop out." it can be sedating and also increase appetite -- good for some ...Read more


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How long does it take for Mirtazapine to get into your system and work for sleep. My Psychiatrist has prescribed 15 mg for me to take at bedtime?

How long does it take for Mirtazapine to get into your system and work for sleep. My Psychiatrist has prescribed 15 mg for me to take at bedtime?

Sedative effect: Yes Mirtazapine should help you sleep. It is called REMeron (mirtazapine) as a Brand name since it helps promote dream sleep stages. Initially you may even sleep too much. The oversedation should wear off after 7 to 10 days. If not, you might ask MD to co-prescribe duloxetine or venlafaxine with it to counter balance the side effects of sedation and increased appetite. ...Read more

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Does mirtazapine put one to sleep better than trazodone? Trazodone doesn't work for me anymore. Do they work similarly?

Does mirtazapine put one to sleep better than trazodone? Trazodone doesn't work for me anymore. Do they work similarly?

Medication effects: I understand your need for good sleep.
Trazodone and Mirtazapine are not sleep medications. They are used to treat Depression.
Stresses of relationships, separation, loneliness, work and past unresolved feelings of worry, fear, sadness, hurt, resentment and guilt can cause difficulty to sleep and result in poor sleep.
See Psychiatrist for Diagnosis, Intensive Therapy, discuss Medications effects. ...Read more

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When the first time I take mirtazapine sandoz, it really helps my insomnia But after 4 mths, I still exp diff in sleep do I need take melatonin too?

Sleep problems: Try to get to bed at the same time every night. Turn off all electric devices an hour before bed time including texting? Listen to soft music. Take a warm bath and drink warm milk before bedtime. Hopeful these few tips with help you rather than taking more medication ...Read more

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What's a good AD that works just like remeron (mirtazapine)? That worked wonders for my anxiety and sleep but it made me irritable. Anything that works just as good

What's a good AD that works just like remeron (mirtazapine)? That worked wonders for my anxiety and sleep but it made me irritable. Anything that works just as good

Difficult to say: Remember everyone's body is different. You really should review this with your prescribing physician. As there are many options which are used to help issues like you describe in addition to the present medications that you appear to be on. Sometimes meds like neurontin (gabapentin) or trazadone are used for exactly what you describe, but again you're best served by someone who knows you well, medically. ...Read more

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What antidepressants work best for trouble falling asleep im on remeron (mirtazapine) 45mg but takes three hours to fall asleep and 70 pound weight gain on this?

What antidepressants work best for trouble falling asleep im on remeron (mirtazapine) 45mg but takes three hours to fall asleep and 70 pound weight gain on this?

Trazadone: Trazadone is fairly safe. It tends to make one sleepy. The work up for insomnia and depression should come first. People with bipolar disase can have problems with antidepressants started without or before mood stabilizers. Make sure you are dealing with the correct diagnosis. ...Read more

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45 mg remeron, 200 Seroquel (bedtime) 90 Cymbalta (duloxetine) 500 Valtrex 1800 gabapentin 7.5 zopiclone (bed) why am I so tired, exhausted falling asleep at work?

45 mg remeron, 200 Seroquel (bedtime) 90 Cymbalta (duloxetine) 500 Valtrex 1800 gabapentin 7.5 zopiclone (bed) why am I so tired, exhausted falling asleep at work?

You are taking a: Number of medications that can cause sedation. Depression can also cause one to feel tired. Please discuss these symptoms with your psychiatrist. Take care. ...Read more

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Can mirtazapine be taken in the day and night ie small dose at nigh to assist sleep, and a higher dose in the day for anxiety?

Can mirtazapine be taken in the day and night ie small dose at nigh to assist sleep, and a higher dose in the day for anxiety?

Yes but...: Mirtazapine may make you drowsy taken in the daytime, that's why it is a bedtime med. For most. It is recommended for depression but does make you sleepy even at small doses. ...Read more

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I think I might have taken 2 of remeron (mirtazapine) 45mg last night im really not surefeel sleep hungover today should I take my regular dose tonight just one?

I think I might have taken 2 of remeron (mirtazapine) 45mg last night im really not surefeel sleep hungover today should I take my regular dose tonight just one?

Remeron (mirtazapine) sleep: The best thing to have your doctor performed a pharmacogenetic test to match the medications with your genetic makeup. This type of pass will tell you if the drug that you're taking is optimal for you. Ninety Milligrams of Remeron (mirtazapine) sounds like a lot of medication but most people don't usually take at the current dose. It is possible that you are considered a poor metabolizer. AssureRx does the test ...Read more

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Dr Is it o k to take tyrptizol with remeron (mirtazapine) at night time for anxiety and sleep. Thanks?

Dr Is it o k to take tyrptizol with remeron (mirtazapine) at night time for anxiety and sleep. Thanks?

Caution: Tryptizol and Remeron (mirtazapine) have drug interactions that may increase risk for serotonin syndrome, eg, causing confusion, increased heart rate, blurred vision. Discuss this combination and doses with prescribing doctor. You might do better with one or the other as both target depression and anxiety. I hope this helps. ...Read more

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I have been on antipsychotics for six years. I can't sleep now without taking a med. Will mirtazapine allow me to sleep every night?

I have been on antipsychotics for six years. I can't sleep now without taking a med. Will mirtazapine allow me to sleep every night?

Uncertain: However, Mirtazapine is often prescribed to help with sleep. In the meantime, how is your sleep hygiene? Maintain a regular bedtime and awakening time schedule including weekends. Get up about the same time every day, regardless of what time you fell asleep. 2. Establish a regular, relaxing bedtime routine. Relaxing rituals prior to bedtime many include a warm bath or shower, aromatherapy, ...Read more

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Dr took me of remeron (mirtazapine) and now on trazadone 150. I am not sleeping through the night. Was this a good change for high trygl?

Dr took me of remeron (mirtazapine) and now on trazadone 150. I am not sleeping through the night. Was this a good change for high trygl?

Yes, Long Term use: Summary: high blood cholesterol and triglycerides could be caused by trazodone, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take seroquel, (quetiapine) and have depression.

We study 4, 663 people who have side effects while taking trazodone from fda and social media. Among them, 189 have high blood cholesterol and triglycerides. Find out below who they are, . ...Read more

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Been on remeron (mirtazapine) 45mg at night for sleep and depression for about 2 years how hard will it be to change I sleep to long and take to long to fall asleep?

Been on remeron (mirtazapine) 45mg at night for sleep and depression for about 2 years how hard will it be to change I sleep to long and take to long to fall asleep?

Talk with doctor: From what a psychiatrist once taught me, once you get over 15mg, the Remeron (mirtazapine) does not have much of a sedating effect anymore, so may not be helping you get to sleep. Do not stop it if you are taking it for depression. Speak to your doctor about other options. ...Read more

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I have anxiety disorder & insomnia. I very sleepy in the day but when night comes I can't sleep even with mirtazapine, what cause this? How to solve?

I have anxiety disorder & insomnia. I very sleepy in the day but when night comes I can't sleep even with mirtazapine, what cause this? How to solve?

How is your sleep: Hygiene? Retire & rise same time each day. Keep bedroom dark & cool & use only for sex & sleep. Turn off tv. No naps. Exercise regularly but not in late evening. No caffeine for 6 hrs & no alcohol or tobacco w/i 2 hrs of sleep. Keep dinner moderate sized & finish at least 2 to 3 hrs before sleep. Can try warm milk, Chamomile tea or melatonin along w light reading, warm bath or lavender scent. ...Read more

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When I lay down at night I take remeron (mirtazapine) 45 at night for depression/sleep and have racing thOughts half the time anything similar to remeron (mirtazapine) sedation?

When I lay down at night I take remeron (mirtazapine) 45 at night for depression/sleep and have racing thOughts half the time anything similar to remeron (mirtazapine) sedation?

See your dr.: If you are having racing thoughts when you take Remeron, (mirtazapine) then you need to be reevaluated for bipolar depresson. Sometimes anxiety can cause racing thoughts as well. You should see your treating physician and report the response you have to your med. Don't use illicit drugs like meth, b/c they can cause similar symptoms. ...Read more

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Remeron (mirtazapine) is affecting my blood sugars. Currently tapering off. Have to eat in middle of night & not sleeping well because of this. I need sleep. Help.

Remeron (mirtazapine) is affecting my blood sugars. Currently tapering off. Have to eat in middle of night & not sleeping well because of this. I need sleep. Help.

Talk w/your doctor: Remeron (mirtazapine) can increase appetite and also be sedating. For the symptoms some people have, these qualities are perfect. Please discuss what you're experiencing with your prescribing physician, because other options are available. ...Read more

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Have a sleep study in a week can I take a Ambien or lunesta (eszopiclone) to fall asleep quick? I take clonazepam 3mg inderal 80mg and remeron 45 mg at night?

Have a sleep study in a week can I take a Ambien or lunesta (eszopiclone) to fall asleep quick? I take clonazepam 3mg inderal 80mg and remeron 45 mg at night?

You will need to: Ask the sleep specialist this specific questions. I have seen sleep specialists tell people to continue their sleep meds and have also seen them instruct patients to hold them. ...Read more

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Is the sleep you get from mirtazapine deep, restorative sleep?

Is the sleep you get from mirtazapine deep, restorative sleep?

The sleep you "get": From Mirtazapine is, in actuality, a SIDE EFFECT of the pill which is a fairly strong ANTI-DEPRESSANT! The sleepiness should pass....
I hope this answers your question!
BTW Mirtazapine is very useful in the early treatment of insomnia associated WITH Depression and THAT may have been the rationale in your case!
Dr Z ...Read more

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Does mirtazapine cause one to sleep too much and is hard to wake up or is it easy to wake up and just enough sleep?

Does mirtazapine cause one to sleep too much and is hard to wake up or is it easy to wake up and just enough sleep?

Everybody different: Every person and every situation is different. It depends on the individual size, weight, physical and mental condition as well as other meds etc etc. You need to discuss with your doctor and monitor the usage under his or supervision. ...Read more

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How can I handle my terrible sleep problems from remeron (mirtazapine) discontinuation?

How can I handle my terrible sleep problems from remeron (mirtazapine) discontinuation?

Insomnia: Try sleep hygiene & get thorough exam by pcp to find out if any medical causes. Refer to diagram. Also, if ok with your doctor, Melatonin may help. ...Read more

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What mg of Mirtazapine should I take for sleep? Currently take half of 45mg. Still not sleeping enough

What mg of Mirtazapine should I take for sleep? Currently take half of 45mg. Still not sleeping enough

Talk to your doctor: Mirtazapine is an antidepressant and it not typically used for insomnia per se. Insomnia can be a symptom of depression and anxiety, and so if the mirtazapine controls depression and anxiety, then sleep should improve. However the dose of the drug should probably not be based solely on the degree of insomnia. Talk to the prescribing doctor about ways to improve your sleep. ...Read more

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Saw a shrink today for sleep problems. Asked me very, very few questions and then prescribed Remeron (mirtazapine). Thoughts? This par for the course? Just do it?

Saw a shrink today for sleep problems. Asked me very, very few questions and then prescribed Remeron (mirtazapine). Thoughts? This par for the course? Just do it?

Common but ok: It is common and acceptable to leave a session regarding sleep issues with a psychiatrist with a prescription for a medication to help sleep. Mirtazapine (Remeron) is an anti-anxiety and antidepressant drug unlike traditional SSRIs. It has a significant drowsiness side effect therefore often prescribed for sleep alone. It can also lead to increased appetite and weight gain. CBT is better option. ...Read more

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The past few days I have not been able to sleep on my remeron (mirtazapine) 45 mgs it has only worked 50 percent of timefor the two years I've been on it change it?

With your 70 pound: Weight gain you should have a sleep study to rule out sleep apnea. I wouldn't recommend anything be changed without consulting your psychiatrist. Best wishes. ...Read more

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I am on remeron (mirtazapine) for anxiety. Is this Med any good for anxiety. It is great for sleep.

Remeron (mirtazapine): It is an Antidepressant with sedative effects at low dose, which helps sleep. Use for anxiety is off-label. ...Read more

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Which dose of mirtazapine will make us feel more sleepy and easy to get sleep? Higher or lower dose?

Which dose of mirtazapine will make us feel more sleepy and easy to get sleep? Higher or lower dose?

Lower supposedly: At dose above 15 it raises norepinephrine which may counteract sedative effect however not always --just saw A pt who got more sedated going from 15 to 30 mg ...Read more

Dr. Heidi Fowler
5,033 Doctors shared insights

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