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Doctor insights on: Why Can It Be Dangerous To Administer Drugs To Patients In Renal Failure

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Why can it be dangerous to administer drugs to patients in renal failure?

Why can it be dangerous to administer drugs to patients in renal failure?

Medications in RF: Many medications and/or the byproducts that come from taking a medication have to get out of your body by way of your kidneys. Also, some medications can, at high levels in your blood, damage your kidneys. Virtually every drug given to a renal failure patient needs to first be looked at from the standpoint of the need to alter dosing before being given. This is really important. ...Read more

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Dr. Tarek Naguib
594 doctors shared insights

Kidney Failure (Definition)

A condition in which your kidneys suddenly stop working normally. Since your kidneys remove waste products and help balance water and salt and other minerals (electrolytes) in your blood, when your kidneys stop working, waste products, fluids, and electrolytes build up in your body. This can cause problems ...Read more


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How do I find out why can it sometimes be dangerous to administer drugs to patients in renal failure?

How do I find out why can it sometimes be dangerous to administer drugs to patients in renal failure?

See your doctor!: Because many drugs are cleared from the body thru kidney into the urine so it passes thru kidneys and can affect the kidneys or it's function! kidney failure if present can worsen if drug dose is not reduced appropriately! ...Read more

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How to manage pain in patient with renal failure?

How to manage pain in patient with renal failure?

Renal failure: Your drug of choice is tylenol (acetaminophen), (acetaminophen) but too much tylenol (acetaminophen) may affect your liver ...Read more

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What food can be taken by renal failure patients?

Many: These patients can still eat any foods, but they just need to decrease the amount of potassium and phosphorous containing foods. Just as a diabetic can eat any sweets, they need to limit it. Renal failure patients need to limit total fluids, potassium and phosphorous. If on dialysis, protein is usually encouraged, but if pre-dialysis, high protein intake may not be a good idea. ...Read more

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Plz tel why renal failure patients should consume low salts ?

Plz tel why renal failure patients should consume low salts ?

The kidneys are sick: When you are young and healthy and the kidneys function normally, they can eliminate salt you take in more efficiently. When the kidneys are sick, they lose the ability to get rid of the extra salt, thus body will accumulate excess salt = bad--cause fluid retention, hypertension, heart failure etc..As a result, many things should be restricted in renal failure patient. Consult doc. Good luck. ...Read more

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Why is clofibrate contraindicated in patients with renal failure?

Clofibrate: Clofibrate is a lipd lowering drug that is metabollized in the liver. Those metabolites are excreted in the kidney. When renal failure/insufficiency happens, the drug itself as well as its metabolites build up in the blood. High concentrations of these metabolites can lead to serious side effects including death. So, don't take Clofibrate if you have renal disease. ...Read more

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How common is renal failure in myeloma patients?

How common is renal failure in myeloma patients?

30% dx; 50% life: Around 30% at diagnosis and about 50% throughout disease course. However, this may be less given newer anti-myeloma agents (?). ...Read more

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Why atracurium is used in both hepatic and renal failure patients?

Why atracurium is used in both hepatic and renal failure patients?

Atracurium use: The reason atracurium can be used in hepatic and renal failure patients is because the breakdown process is not dependent on kidney are liver function. The drug is broken down through a process called the hoffman eleimination that is independent of organ activity. However, the main metabolite is laudanosine and it can acumulate in elderly renal and liver failure patients. ...Read more

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Why is atracurium used for both hepatic and renal failure patients?

Metabolism: Atracurium is a non-depolarizing neuromuscular blocker. It is metabolized via a process called Hoffmann elimination (ester hydrolysis which is independent of renal, hepatic or enzymatic function). Since you don't need the liver or kidney to metabolize the drug, it is a paralytic often used for patients with renal and/or hepatic failure. ...Read more

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Can adding baking soda to renal failure patients help?

Yes: Correcting acidosis with sodium bicarbonate has been shown to slow down the progression of chronic kidney disease. Please consult your kidney doctor regarding the appropriate dosage. ...Read more

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What would be the life expectancy for younger patients with stage IV renal failure?

Stage 4 RF: Stage 4 patients have GFR between 15 & 30. I approach this from the standpoint of preserving what kidney function you have, not life expectancy. Ways to do that - watch your diet and avoid foods that have lots of potassium and salt; limit protein intake; watch your weight; take all medicines prescribed; see your doctor regularly. Look here : http://www.Kidneyfailureweb.Com/prognosis/221.Html. ...Read more

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Why atracurium is used in both patients with hepatic and renal failure?

Why atracurium is used in both patients with hepatic and renal failure?

Elimination mechani: Atracurium is not dependent on liver or kidneys for elimination, so it wears off normally in these patients. ...Read more

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Why are renal failure patients anemic?

Why are renal failure patients anemic?

Reducerythropoietin : In significant chronic renal failure the hormone erythropoietin is produced in lower amounts. If the anemia is severe and there is no other type of anemia (usually less that 11) and if pt is symptomatic this substance can be given in form of injection (procrit (epoetin alfa) and others). ...Read more

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Does biotin and chromium help patients with renal failure?

Does biotin and chromium help patients with renal failure?

No they do not: And like all other supplements, should be avoided in anyone, particularly someone with renal failure. ...Read more

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Is it possible to reverse chronic renal failure in a patient?

Is it possible to reverse chronic renal failure in a patient?

Renal failure: It is difficult to reverse renal failure, but with strict diet and blood pressure control the progression can be stabilized. Also staing well hydrated can help also. ...Read more

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Can you please explain why ffp is given to acute renal failure patient?

Can you please explain why ffp is given to acute renal failure patient?

Risk of bleed: Ffp has coagulation factors and is usually given to decrease the risk of bleeding. Some kidney diseases are also associated with abnrmalities in coagulation, therefore may need ffp. Kidney disease per se can increase the bleeding risk as some cells do not work well in kidney failure. Usually FFP are given when there is ongoing bleed, or there is high risk of bleed, or when procedure is planned. ...Read more

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What is the cause of sudden fever intermittent in patient with renal failure?

What is the cause of sudden fever intermittent in patient with renal failure?

Need a lot more info: You've given too little detail, so you'll need to provide us with more. When you say renal failure, do you mean end-stage renal disease, acute renal failure, chronic renal failure, or something else? What other things are happening with the patient besides the occasional fever? What region of the world is the patient in? Any other concomitant illnesses? How high is the fever? ...Read more

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What are good ways to boost hemoglobin level for patient suffering from end stage renal failure?

Anemia and ESRD: This patient must be on dialysis. At his dialysis center, he should be receiving Epogen (epoetin alfa) to increase the hb level. There are some people that have a problem with EPO and do not raise their hb level, due to anti-epo antibodies and is rare. Other causes of no increase of hb levels are blood loss from the GI tract, hemolysis and high parathyroid hormone levels. Ask the patient's nephrologist about it. ...Read more

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What can be done to prevent renal failure or derangements in myeloma patients?

What can be done to prevent renal failure or derangements in myeloma patients?

Disease treatment: The only effective prevention for the renal disease associated with myeloma is the effective treatment of the underlying disease. ...Read more

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What would glucose levels be like in a non-diabetic patient having chronic renal failure?

Normal: If a patient is not diabetic there blood sugar should be in the normal range. Even in if in chronic renal failure. If running high may be due to certain medications which might be used to treat some other condition. ...Read more

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Is jaundice in renal failure patients and indication of liver failure as well?

Is jaundice in renal failure patients and indication of liver failure as well?

Many causes: Many potential causes of jaundice but not renal failure alone and haudice does not equate to liver failure causes and be meds, viral, infection, gallstones , etc extensive lab and ultrasound or cat scan would be needed to determine cause. ...Read more

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Why would a patient in renal failure get decreased cardiac function?

Other way around: Usually it is the decreased cardiac function that leads to kidney failure due to lack of blood flow. However, the two illnesses in general share many contributing factors like high blood pressure and diabetes. ...Read more

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Does a heart / renal failure patient feel anything when their heart stops?

Does a heart / renal failure patient feel anything when their heart stops?

Asystole, or fibrill: If the heart ceases all electrical activity (asystole), the patient may feel momentary light-headedness before passing out. If, instead, the patient suffers ventricular fibrillation, there may be some palpitations before passing out. ...Read more