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Why Can It Be Dangerous To Administer Drugs To Patients In Renal Failure
Medications in RF: Many medications and/or the byproducts that come from taking a medication have to get out of your body by way of your kidneys. Also, some medications can, at high levels in your blood, damage your kidneys. Virtually every drug given to a renal failure patient needs to first be looked at from the standpoint of the need to alter dosing before being given. This is really important. ...Read moreSee 1 more doctor answer
The kidneys do several tasks. Dialysis is necessary when one or more of the following occur, that can't be remedied or palliated with medications: 1. Insufficient clearance of daily toxins in food and metabolic waste 2. Insufficient clearance of excess water 3. Dangerous electrolyte imbalance, ...Read more
How do I find out why can it sometimes be dangerous to administer drugs to patients in renal failure?
Many: These patients can still eat any foods, but they just need to decrease the amount of potassium and phosphorous containing foods. Just as a diabetic can eat any sweets, they need to limit it. Renal failure patients need to limit total fluids, potassium and phosphorous. If on dialysis, protein is usually encouraged, but if pre-dialysis, high protein intake may not be a good idea. ...Read more
BP control: High salt diet promotes water retention which results in elevation in blood pressure and swelling in the legs. The water pills (diuretics) work better if a patient consumes less salt. So if you want good BP control and volume control with less medications than low salt diet is the way to go. ...Read moreSee 1 more doctor answer
Clofibrate: Clofibrate is a lipd lowering drug that is metabollized in the liver. Those metabolites are excreted in the kidney. When renal failure/insufficiency happens, the drug itself as well as its metabolites build up in the blood. High concentrations of these metabolites can lead to serious side effects including death. So, don't take Clofibrate if you have renal disease. ...Read more
Atracurium use: The reason atracurium can be used in hepatic and renal failure patients is because the breakdown process is not dependent on kidney are liver function. The drug is broken down through a process called the hoffman eleimination that is independent of organ activity. However, the main metabolite is laudanosine and it can acumulate in elderly renal and liver failure patients. ...Read more
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