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Why Are Sclera Blue In Osteogenesis Imperfecta
Osteogenesis imperfecta is a condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more
Thin sclera: Osteogenesis imperfecta amongst its other problems, produces a thinning of the white outer coat of the eyeball, the sclera. Because of this the dark inner lining, the uvea, adds its coloration to light striking the thinned sclera and the result is a blue color. The condition does not actually infuse the sclera with blue - it is an optical effect. ...Read moreSee 2 more doctor answers
I am 28 & when move my eyes right and left i see ting of blue sclera is it normal or any kind of problem and there is no genetic osteogenesis problm?
Blue Sclera: There are other causes of blue sclera besides osteogenesis imperfecta. Other causes can include: medication effects, topical eye drops, exposure to silver compounds, collagen synthesis disease, and alkaptopuria. It would be best to have this evaluated by an opthomologist. ...Read moreSee 1 more doctor answer
Underlying pigment: Normal sclera is opaque and quite white. If it thins out for some reason, the underlying pigmented uvea adds a bluish hue to the sclera at that point. Things that thin the sclera are certain inherited conditions like ehlers-danlos or trauma, elevation of the eye pressure in the young and some chronic inflammatory eye diseases. ...Read more
OI: In medicine, blue sclera can be the sign of a serious medical condition. The most well-known is osteogenesis imperfecta - a genetic disease in which the bones are brittle and break very easily. Kids have a horrible life because of this. A very superficial example is in m night shyamalan's unbreakable. ...Read moreSee 1 more doctor answer
See below:: Blue sclerae are most importantly associated with types i and ii osteogenesis imperfecta, the latter of which is fatal and thus not seen in adult practice. Other associations include: ehler's danlos syndrome pseudoxanthoma elasticum marfan's syndrome a blue sclera may also be acquired through long-term use of corticosteroids. ...Read more
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