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Doctor insights on: Why Are Doctors Recommending Zantac For An Allergic Reaction Or Hives

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Why are doctors recommending Zantac (ranitidine) for an allergic reaction or hives?

Why are doctors recommending Zantac (ranitidine) for an allergic reaction or hives?

Good question: Hives (or urticaria) represent a sensitivity to something dilating the small vessels under the skin, causing a raised pink lesion; if u press on it, it will blanch, let it go it pinks up again. Many causes: foods, chemicals, perfumes, very often stress. Stress can increase acid formation in stomach, Zantac (ranitidine) reduces it. Over 50% of time, one can't find cause. I treat initially c antihistamines. ...Read more

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Dr. John Chiu
2,586 doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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I had a allergic reaction to ciprofloxacin and the er doctor prescribed me zantac (ranitidine) for the allergic reaction is that normal?

I had a allergic reaction to ciprofloxacin and the er doctor prescribed me zantac (ranitidine) for the allergic reaction is that normal?

No: Zantac (ranitidine) (a H2 reverse agonist) does nothing by itself to control allergic reactions although it may at times be helpful when used together with a classical antihistamine particularly for itchy hives. ...Read more

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Doctor says I have Angioedema and hives told me to take Allegra 180mg in morning and Zyrtec10mg at night and Zantac (ranitidine) 150mg does this sound right.

Doctor says I have Angioedema and hives told me to take Allegra 180mg in morning and Zyrtec10mg at night and Zantac (ranitidine) 150mg does this sound right.

Yes: the use of second generation antihistamines as the ones prescribed to control hives and angioedema is right, use of zantac (ranitidine) is controversial nowadays, however, More important is seeing an allergist/dermatologist for management,trying to find a cause and monitor treatment.If angioedema is causing any respiratory problems,although rare, an epinephrine pen may be needed, check aaaai.org 4 an allergist ...Read more

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My allergic drug reactions usually consist of hives. Now that i take xyzal&zantac, am i at least somewhat protected from drug reactions if one occurs?

My allergic drug reactions usually consist of hives. Now that i take xyzal&zantac, am i at least somewhat protected from drug reactions if one occurs?

Yes: Both of those medicines help treat allergic reactions, but if you are very sensitive you still may get hives. If you have breathing difficulties from a reaction seek emergency care immediately. ...Read more

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If a person pre-medicates w/xyzal & zantac, (ranitidine) can they take an nsaid drug, if that drug has caused minor hives in the past? Get skin reaction only.

If a person pre-medicates w/xyzal & zantac, (ranitidine) can they take an nsaid drug, if that drug has caused minor hives in the past? Get skin reaction only.

Possibly: Both xyzal (levocetirizine) & zantac have anti-histamine effects & may decrease or eliminate a mild reaction to nsaid. However, this can be dangerous. Repeat exposures to something you are allergic to can be more severe, including breathing & swallowing difficulties, swelling of the face, lips, tongue or mouth. 6 classes of nsaids exist; you may not be allergic to other NSAID classes. An allergist may help a lot. ...Read more

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Doc,safe to take a pill of probiotic everyday?can it cause hives,allergies and any other side effects? I had high IGe .any relation to probiotics ?

Doc,safe to take a pill of probiotic everyday?can it cause hives,allergies and any other side effects? I had high IGe .any relation to probiotics ?

Usually: Most people can tolerate probiotics but extremely high doses can cause gastrointestinal upset. I am not aware of any link to hives or allergic diseases. In fact, there are studies showing that probiotics may lower the chance of developing eczema for infants. Do note that not all probiotics are created equal and different strains may be needed for different folks- thus no universal good guy. ...Read more

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Can I take a 180 mg OTC Allegra (fexofenadine) twice a day? Severe allergies (hives and itching), unable to see doctor for another week or so. Need relief.

Can I take a 180 mg OTC Allegra (fexofenadine) twice a day? Severe allergies (hives and itching), unable to see doctor for another week or so. Need relief.

Don't wait 4 a week: please see an allergist/your doctor sooner, two tablets of allegra (fexofenadine) 180 is already over precsribed for OTC strength, you need to be evaluated and prescribed prescription strength meds, goodluck ...Read more

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I'm 21 year old male and been having this feeling of something stuck in my throat I have been taken 150m of zantec my doc gave me for GERD but the feeling still is there what can this be the acid allergies or just anxiety?

I'm 21 year old male and been having this feeling of something stuck in my throat I have been taken 150m of zantec my doc gave me for GERD but the feeling still is there what can this be the acid allergies or just anxiety?

Unclear : This is a common symptom, sometimes referred to as a globus sensation. It is real, but there isn't anything actually stick in the throat. Common with gerd, but relationship to reflux also uncertain. It is not dangerous. Hope this helps. ...Read more

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+ana, postive 320 and anti ribosomal p antibodies. All other labwork is normal. Symptoms are photosenstivity, livedo reticularis, mouth sores.....?

+ana, postive 320 and anti ribosomal p antibodies. All other labwork is normal. Symptoms are photosenstivity, livedo reticularis, mouth sores.....?

See allergist and dermatologist: Your symptoms and clinical picture suggests to different diagnosis as -either simple allergic condition ,or connective tissue disease,lupus erythrommatosus .You should be further investigated as blood test and may be skin biopsy may give clue to diagnosis .Avoid sun exposure ,taking anti allergic medication and steroids may help .Consult the dermatologist ...Read more

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Is it possible that Zantac, being a histamine blocker, could cause higher histamine production when coming off of it, resulting in development of allergies? For example consuming diet soda can result in insulin spikes in some cases, possibly leading to di

Is it possible that Zantac, being a histamine blocker, could cause higher histamine production when coming off of it, resulting in development of allergies? For example consuming diet soda can result in insulin spikes in some cases, possibly leading to di

No: Zantac (ranitidine) is a histamine 2 receptor reverse agonist and would not significantly affect histamine production.when withdrawn. There is a theoretical possibility that Zantac (ranitidine) itself may lead to more histamine release by blocking the histamine 2 receptor(which acts as a feedback switch) but this has not been clinically a significant issue. ...Read more

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My wife had sushi for dinner last nite today she has wrist & knee pain with a rash. Could this be allergic reaction. Is a doctor visit recommended?

My wife had sushi for dinner last nite today she has wrist & knee pain with a rash.  Could this be allergic reaction. Is a doctor visit recommended?

Doctor visit needed: Schedule an appointment with an immunologist. Get a thorough list of ingredients in the sushi she ate. Joint swelling and pain is not a typical allergic reaction (type i hsr). Blood and skin testing might be warranted and an Epipen (epinephrine) might be prescribed. ...Read more

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What's better for hives, Zantac 150 or benadryl (diphenhydramine)?

What's better for hives, Zantac 150 or benadryl (diphenhydramine)?

Benadryl (diphenhydramine): Benadryl (diphenhydramine) is better than zantac. Benadryl (diphenhydramine) is an h1 blocker, zantac is not. I like Allegra more than Benadryl (diphenhydramine) because Allegra does not cause drowsiness. ...Read more

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Is Zantac (ranitidine) also good for hives?

No: It used to be thought that the addition of medications such as ranitidine or Famotidine may be helpful since they do block one of the histamine receptors. However, current guidelines do not support the use of the medications in the treatment of hives. ...Read more

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Zantac (ranitidine) and zrytec for chronic hives?

Yes: You can take it and should til you find out the cause , do see an allergist. ...Read more

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How long do you need to take allegra and Zantac (ranitidine) to treat hives?

Hive treatment: Hives can be acute, lasting less than 6 weeks or chronic lasting greater than 6 weeks, (possibly even for years). Antihistamines might control hives but could be needed long-term. Try stopping daily antihistamines once every month for a few days to see if they are still needed. See an allergist to help find the underlying cause if your pcp fails to discover a trigger. ...Read more

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Whenever I get hot I start to itch, I had hives prior but they're gone I'm currently on zantac (ranitidine) and Zyrtec (Costco brand). It doesn't seem to work.

Whenever I get hot I start to itch, I had hives prior but they're gone I'm currently on zantac (ranitidine) and Zyrtec (Costco brand). It doesn't seem to work.

Cholinergic ?: There is a condition known as cholinergic urticaria (small bumps) which occurs during the cooling down period after a rise in core body temperature (hot shower, exercise, stress etc). If this fits your pattern, then try taking the antihistamine up to every 8 hrs to see if this may work. ...Read more

Dr. Al Hegab Dr. Hegab
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Zantac (ranitidine) has histamine ingredients. I'm taking it recently.noticed some inverse effect,my hives is not popping out too!It should be antihistamine right?

Dr. Al Hegab Dr. Hegab
2 doctors agreed:
Zantac (ranitidine) has histamine ingredients. I'm taking it recently.noticed some inverse effect,my hives is not popping out too!It should be antihistamine right?

Zantac (ranitidine): Is an antihistamine itself, it blocks H2 receptors, histamine has more than one type of receptors in the human tissues. H1, blocked by the usual antihistamines, H2, plays a role in stomach acid regulation, which zantac (ranitidine) blocks. Zantac at times is used in severe allergic reactions or severe urticaria, together with H1 blockers to control symptoms, so your deduction is right ...Read more

Dr. Sanjay Talati
640 doctors shared insights

Ranitidine (Definition)

Treats and prevents heartburn with acid indigestion. Also treats stomach ulcers, gastroesophageal reflux disease (gerd), and conditions that cause your stomach to make too much acid (such as zollinger-ellison syndrome). This medicine ...Read more


Dr. Lonnie Smith
3 doctors shared insights

Hives (Definition)

An outbreak of red bumps or wheals that appear quickly after exposure to certain allergens (foods, medications, other substances). They can vary in size, are itchy, can burn, and can last for up to ...Read more