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Doctor insights on: Why Are Clostridium Difficile Infections Hard To Treat

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Why are clostridium difficile infections hard to treat?

Why are clostridium difficile infections hard to treat?

It produces spores: Partly it is the persons immune system and general health that makes it recur more often. The main problem is it comes back after treatment. Clostridium produces endospores. Endospore is is a tough structure in which the bacteria is dormant and not reproducing. Antibiotics don't affect the spores so after the symptoms are gone, the spores activate and then cause reinfection. ...Read more

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Dr. Sanjiv Kaul
9 doctors shared insights

Infection (Definition)

Infections are invasions of some other organism (fungus, bacteria, parasite) or viruses into places where they do not belong. For instance, we have normal gut bacteria that live within us without causing problems; however, when those penetrate the bowel wall and enter the bloodstream, ...Read more


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Is it true that the use of fecal enemas is way to treat severe clostridium difficile infections?

Is it true that the use of fecal enemas is way to treat severe clostridium difficile infections?

Absolutely True: It's amazing, and for some people seems disgusting, but it actually works to recolonize the gut. The formal name is fecal or stool transplant, and as you say it essentially involves introducing fecal matter from a healthy donor into the gut of a person with c. Diff. Still experimental and not widely used yet. I have condensed a medlineplus link: see http://tinyurl.Com/7r27abk. ...Read more

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What are the tests for clostridium difficile infection?

What are the tests for clostridium difficile infection?

C. diff: Both the bacterial toxin and the gene coding for the toxin can be found in the diarrheal stool. Additionally, the diarrhea has a peculiar mousy/musty aroma. ...Read more

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What are the symptoms of clostridium difficile infection?

Fever diarrhea: C. Difficile is a common bacteria that causes problems when the norm/friendly gut bacteria is weakened or gone due to antibiotics usually. Symptoms are abdominal pain, fever, diarrhea, often with blood present. It can be a serious and even deadly infection, so please get checked if you have these symptoms. ...Read more

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What is the incidence of clostridium difficile infection in the us?

C.Diff: Approximately 20% of individuals who are hospitalized acquire c difficile during hospitalization, and more than 30% of these patients develop diarrhea. Thus, c difficile colitis is currently one of the most common nosocomial infections. ...Read more

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What are the tests for clostridium difficile infections?

What are the tests for clostridium difficile infections?

Stool test: The most commonly used tests for c diff are two different stool tests. One test looks for the unique toxin which c diff produces that causes the diarrhea. The other test searches for the gene (dna) that is specific to c diff and encodes the information to produce the toxin. ...Read more

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What is the likelihood of a relapse with clostridium difficile infections?

What is the likelihood of a relapse with clostridium difficile infections?

Common: There is a small percentage of c. Dificile infections that recur so it does happen. However with newer treatments it happens less. You may want to look into sarcomyces boullardi[(forgive me if mispelled) or florastor which for a long time was used in europe to treat c. Dif infections...With huge success. Check out your local healthfood store; or ask your doctor for more info. ...Read more

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Are there home remedies that are effective in fighting clostridium difficile infections?

Are there home remedies that are effective in fighting clostridium difficile infections?

Gross but Good: Studies show that consuming the stool (feces) of a close contact is just as effective in treating clostridium difficile associated diarrhea (cdad) as some of the leading prescribed medications. The papers describe the procedure even noting the name and model of the blender used to mix the #!#@ (feces). Gross but good. ...Read more

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I am recovering from a clostridium difficile infection. I heard recurrence happens, how likely is it ? Is there a way to prevent it ?

I am recovering from a clostridium difficile infection. I heard recurrence happens, how likely is it ? Is there a way to prevent it ?

Unlikely: Most people do not relapse. Older people seem to be highest risk. A well accepted and proven preventative option does not yet exist. Many infections don't need antibiotics (sinus, bronchitis, ear) so avoiding antibiotics if you can - one option. ...Read more

Dr. Rick Koch
150 doctors shared insights

Gestational Hypertension (Definition)

BP at 140/90 at 20 wks pregnancy with no other signs of kidney involvement. Benign condition if nothing else happens, but can worsen to serious condition of pre-eclampsia in many cases. Needs to be ...Read more


Dr. Stephen Scholand
429 doctors shared insights

Clostridium Difficile (Definition)

C. Diff, it is a spore forming bacillus that when the micro environment of the colon is modified by antimicrobials, it can germinate and elaborate a toxin causing pseudo membranous colitis, ...Read more