Doctor insights on:
Who Should Avoid Taking An Aldosterone Antagonist
I have been taking spiro for hyperaldosteronism for a year. By now has my aldosterone level returned to normal and will i ever be able to stop taking ?
It is unlikely : If you have conn disease you will likely need for long. But have to know if your hyperaldestronism is temporary to suggest duration of treatment. ...Read more
Correct measurement: Aldosterone levels vary quite a bit with even position. First make sure that it is measured correctly. Truly high levels of aldosterone may be related to overgrowth or tumor in the adrenal gland, or be secondary to high renin levels driving higher production. Further labs and imaging may be needed to accurately diagnose. Discuss with your doctor. ...Read moreSee 2 more doctor answers
Physiology: Hi. Aldosterone is primarily there to regulate renal handling of sodium, potassium, and acid. Urine concentration/osmolality is more a function of anti-diuretic hormone (ADH) regulating tubular luminal (phenobarbital) water channels and the ambient solute gradient in the loop of Henle. Water follows sodium in general, but the kidneys place quite a degree of regulation on this, so aldo has trivial effect on conc. ...Read more
Function Aldosterone: 48 F form MI asks what is "function" of aldosterone. Its first function is to keep you from dying of salt depletion. Second it keeps you from dying of high blood potassium. It acts on the kidney to increase salt (Na) retention when your body salt is too low: such as from diarrhea, vomiting, sweating, low alt diet. If you have no aldo you die of salt depletion unless you eat salt by handful. ...Read moreSee 1 more doctor answer
ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read moreSee 1 more doctor answer
CHF: These are secreted by the body intent on increasing intravascular volume. They can be an appropriate compensatory mechanism when volume is low, or they can aggravate hypertension and chf, when they become excessively secreted. ...Read more
An article from a credible source says to be tested for aldosterone when having a hypertension resistant situation (like me). Agree with testing?
See below: You shoulg be tested for several things, given your situaton. ...Read more
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