Doctor insights on:
White Matter Microvascular Ischemic Disease
Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more
White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more
Lack of blood deep : In the brain. This condition is most commonly seen in individuals with one or all of the following: 1. Hypertension 2. Diabetes 3. Hyperlipidemia (high cholesterol) 4. Cigarette smoking 5. Family history of stroke of course there are others but these are most important. Please meet with your neurologist to discuss why and what you can do to help your situation. Good luck and well wishes. ...Read more
Parse the words: Chronic = long-standing. Microvascular = small blood vessel. Ischemic = insufficient blood flow. Technically such a condition can affect any organ in the body but this condition gets most attention due to neurologic involvement. Certain genetic & environmental factors contribute to this condition--that is, there is more than one cause. ...Read more
See comments: Are you referring to radiology reading of an MRI of brain? In elderly, often thought that white matter lesions are associated with "microvascular angiopathy", sign of potential atherosclerosis. Maybe potential stroke risk, especially lacunar infarct, but not straightforwards. Your physician needs to assess stroke risk. Spots more likely from migraine or prior injury. ...Read more
Is stable bilateral frontaoparietal white matter t2w/flair hyperintense signals, probably chronic microvascular ischemic changes called mild stroke?
What does coronary occlusion acute, arterio-sclerotic cardio vascular disease and acute myocardial infarction mean?
Mom is 79 brain CT scan: moderate cerebral volume loss, mild widening of the cortical sulci, mild white matter microvasc. Ischemic disease serious?
Depends: Most likely these are aging changes that have occurred with time. ...Read more
Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. Is this serious?
NONSPECIFIC : Although the films were read as suggesting ischemia, location might also suggest prior head trauma, congenital lesions of no consequence, genetic or hereditary issues, even underlying inflammatory condition. This is only "serious", if clinically you are having stroke symptoms or you possess uncontrolled blood pressure or elevation of blood lipids. Likely quite non-diagnostic. ...Read moreSee 1 more doctor answer
Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. What does this mean?
Subcortical ischemia: This translates to changes in the smaller blood vessels that lead to loss of blood flow to the area and then scarring. Somewhat like a small silent stroke and frequently seen in people with migraines. The opinions about this have swayed from very worried, to common and mundane and more recently back to looking to stop the damage (help the blood flow, oxygen and glucose status optimize). ...Read more
81 year old mother, CT periventricular deep white matter changes and moderate small vessel iscjaemic disease. serious?
Brain MRI findings. Tiny nonspecific periventricular and subcortical white matter. Possiblities mini strokes, vasculaties, ms. I shuffle my feet & drop?
Nonspecific finding: White matter changes that are nonspecific are sometimes over reported or under-reported on MRI studies. They may be misread and really suggest MS, they may be a finding with no clinical relevance. Usually it is the latter. It sounds like the brain MRI did not help that much. So you shuffle your feet and drop? What do you mean by drop? Do you have numbness? Why was the brain MRI done? ...Read moreSee 2 more doctor answers
Medical therapy: if one has a tendancy for vascular disease - coronary artery disease being one area we are concerned about - then we have a reasonable set of recommendations to minimize disease progression, and even cause regression. These recs include: optimal weight, daily exercise, low fat/veg/mediterranean diets, lipid Rx, aspirin. other medicines like beta blockers or acei inhibitors can be helpful ...Read more
Can ischemic small vessel disease cause gliosis? How would ischemic small vessel disease be treated in a minimal area of white matter in the brain?
Affects whole brain: Strictly speaking, diffuse cerebrovascular(cv) disease refers to an entity that affects all of the vessels throughout the brain.That is both the large and small vessels. Many times the diffuse cv disease is inferred by the clinical findings or MRI findings-ie. Signs of stroke/ischemia in multiple areas throughout the brain. Diffuse processes like diabetes or lupus are examples that can lead to this. ...Read more
Why did you get it?: If the radiologist knew your age and still read the report in that way I think that is a little bit unusual. But, it kind of depends on the reason you had the MRI done in the first place. Typically, that type of a read would be more common for someone who had long-standing hypertension, diabetes, high cholesterol, smoker for many years and so forth. Do you have a copy of the report or the films ...Read more
Lack of blood flow: Causing a loss of myelin in the central nervous system. This condition is most commonly seen in the periventricular white matter in both hemispheres. There appears to be 5 major risk factors for these lesions: 1. Hypertension 2. Hyperlipidemia 3. Diabetes 4. Smoking 5. Family history of stroke please be evaluated to minimize the risk for stroke and consider antiplatelet therapy if appropriate. ...Read more
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