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Doctor insights on: White Matter Microvascular Ischemic Disease

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What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation.

White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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My MRI shows "MILD WHITE MATTER MICROVASCULAR ISCHEMIC CHANGES". Could this be a reason for my memory issues and word-finding issues?

My MRI shows "MILD WHITE MATTER MICROVASCULAR ISCHEMIC CHANGES". Could this be a reason for my memory issues and word-finding issues?

Vascular dementia.: The second most common form of dementia (after Alzheimer's) is vascular dementia, also known as multi-infarct dementia. An accumulation of tiny infarcts, much like those imaged on your MRI, leads to symptoms of dementia. We tend to see this form of dementia in people with hypertension, diabetes, high cholesterol. So this could be related to your symptoms. Ask your doctor if u can take aspirin.

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Do symptoms with microvascular ischemic disease of brain return once they are gone?

Do symptoms with microvascular ischemic disease of brain return once they are gone?

Can return: Ischemic microvascular of the brain is usually a radiologic description of certain findings on ct or mri. These findings are typically seen in pts. With poorly controlled hypertension and/or diabetes mellitus. Symptoms can return/worsen if the underlying risk factors are not addressed. Though the imaging abnormalites rarely return to normal, treatment can prevent progression.

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Is ischemic microvascular brain disease related to stroke?

See comments: Are you referring to radiology reading of an MRI of brain? In elderly, often thought that white matter lesions are associated with "microvascular angiopathy", sign of potential atherosclerosis. Maybe potential stroke risk, especially lacunar infarct, but not straightforwards. Your physician needs to assess stroke risk. Spots more likely from migraine or prior injury.

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77 year old's MRI - chronic microvascular ischemic disease & shrinking of brain. No diabetes or high BP. Hasn't smoked for 30 yrs. What's the cause?

77 year old's MRI - chronic microvascular ischemic disease & shrinking of brain. No diabetes or high BP. Hasn't smoked for 30 yrs. What's the cause?

Well that's the question: As we age the brain tends to lose fluid content. There are many seniors who do not have this issue while others do. The micro vascular ischemia is not dependent upon diabetes but small vessels that become blocked by many things including blood clots and cholesterol. Often times it doesn't affect the function of the individual. Occasionally it will.

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What is chronic white matter ischemic disease?

What is chronic white matter ischemic disease?

Lack of blood deep: In the brain. This condition is most commonly seen in individuals with one or all of the following: 1. Hypertension 2. Diabetes 3. Hyperlipidemia (high cholesterol) 4. Cigarette smoking 5. Family history of stroke of course there are others but these are most important. Please meet with your neurologist to discuss why and what you can do to help your situation. Good luck and well wishes.

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Can ischemic small vessel disease cause gliosis? How would ischemic small vessel disease be treated in a minimal area of white matter in the brain?

Can ischemic small vessel disease cause gliosis? How would ischemic small vessel disease be treated in a minimal area of white matter in the brain?

Yes.: White matter changes frequently seen on brain MRI are the result of chronic small vessel ischemic disaease and it is the resulting small focus of gliosis that shows on the MRI imaging. Treating your underlying cardiovascular heath is key, not the MRI finding.

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I recently had an MRI of the brain. The results where as follows mild atrophy and mild periventricular white matter ischemic small vessel disease. Wh?

I recently had an MRI of the brain. The results where as follows mild atrophy and mild periventricular white matter ischemic small vessel disease. Wh?

Arteriosclerosis: You are taking hydrocodone, tramadol & Lyrica (pregabalin) for nagging pain plus Ambien for sleep and Buspirone for anxiety. Combination is heavy stuff. Had migraine but not any more? Microvascular disease is the blockage of tiny vessels-arteriosclerosis. These can happen in heart & kidney as well. Check your lipid profile and possible use of statin. For headache & reevaluation of all your meds see neurologist.

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Diagnose of microvascular ischemic dissease in brain. Symptoms are now gone will they possibly return?

Diagnose of microvascular ischemic dissease in brain. Symptoms are now gone will they possibly return?

Can return: Ischemic microvascular of the brain is usually a radiologic description of certain findings on ct or mri. These findings are typically seen in pts. With poorly controlled hypertension and/or diabetes mellitus. Symptoms can return/worsen if the underlying risk factors are not addressed. Though the imaging abnormalites rarely return to normal, treatment can prevent progression.

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Microvascular chronic ischemic in brain can affect memory?

Microvascular chronic ischemic in brain can affect memory?

Sure can: We term multiple small strokes, lacunar infarcts, and these can mount up and produce "etat lacunaire", or full blown vascular dementia. Here, the job involves prevention with an appropriate stroke anti platelet, or anti-coagulant approach.

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Is it normal for a 42 yr old female to have chronic microvascular ischemic changes of the brain & what could be the cause? History chronic muscle pn

Is it normal for a 42 yr old female to have chronic microvascular ischemic changes of the brain & what could be the cause? History chronic muscle pn

Brain: My opinion on chronic microvascular changes...Most important is how bad. Sometimes there are a few small speckles seen in people with migraines that are definitely not worrisome. Otherwise risk factors for this are: smoking, high bp/cholesterol, diabetes, drug use, and genetics...Among other rare causes. My biggest recs would be to work on any changeable things like some of these.

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Hello dr, I had a MRI of my brain. It came back as slight chronic microvascular ischemic changes. What does that mean? Also what does a air cell mean?

Hello dr, I had a MRI of my brain. It came back as slight chronic microvascular ischemic changes. What does that mean? Also what does a air cell mean?

Aging changes: As we get older, arteries harden and we see small vessel changes in the brain due to aging. They simply mean the brain doesn't work as well as it did when we are young and mostly attest to our slowly diminishing function. These are microvascular ischemic changes. You probably don't notice these changes. Air cells are bony areas of the skull with air spaces in them- normal.

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My grandpa have chronic microvascular ischemic changes. He has deficiency in vit B12, show low O2 in the brain, have memory loss, his behavior has changed?

My grandpa have chronic microvascular ischemic changes. He has deficiency in vit B12, show low O2 in the brain, have memory loss, his behavior has changed?

? vascular dementia: 1. Get the vitamin B-12 into normal range with injections. 2. He may have had small strokes which need to be prevented with medication. 3. Could have Alzheimer's. Any of above separately or together could affect memory and behavior. A neurologist can help.

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What is the meaning of chronic ischemic changes in bilateral frontparietal sub cortical white matter. What is the medicne for this?

What is the meaning of chronic ischemic changes in bilateral frontparietal sub cortical white matter. What is the medicne for this?

Aspirin...: Blood supply to the mentioned areas are compromised. HTN, DM, Vasculitis, Atherosclerosis, Embolism, can be responsible. Starting with aspirin and doing WU is better.