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Doctor insights on: White Matter Disease Causes

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I have white matter disease and the neurologist didn't really tell me that it would cause cognitive issues. Will these issues get better?

I have white matter disease and the neurologist didn't really tell me that it would cause cognitive issues. Will these issues get better?

Maybe...: Really depends on the location and the number of white matter lesions. In demyelinating disorders such as multiple sclerosis if having a increase lesion burden, cognitive dysfunction will occur. Otherwise, the number and location is important to determine whether there'll be any memory or cognitive issues. ...Read more

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White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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What is chronic white matter ischemic disease?

What is chronic white matter ischemic disease?

Lack of blood deep : In the brain. This condition is most commonly seen in individuals with one or all of the following: 1. Hypertension 2. Diabetes 3. Hyperlipidemia (high cholesterol) 4. Cigarette smoking 5. Family history of stroke of course there are others but these are most important. Please meet with your neurologist to discuss why and what you can do to help your situation. Good luck and well wishes. ...Read more

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Mild supratentorial white matter disease--what is this?

Mild supratentorial white matter disease--what is this?

Maybe of no signif.: White matter lesions may be caused from a host of circumstances, such as migraine, prior head or neck trauma, hardening of the arteries, inflammation like multiple sclerosis, prior small strokes, effect of some medications such as methotrexate, and is not specific. The location of your concern maybe actually a chronic, lifelong issue. Consult your doctor. ...Read more

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I had a MRI that showed minimal white matter disease that was not addressed. Now im having signs of MS. ?

I had a MRI that showed minimal white matter disease that was not addressed. Now im having signs of MS. ?

Get re-evaluated: The MRI may well be nonspecific, and the result of migraine, old head trauma, smoking, etc. But if you now have neurological symptoms, and "signs", this needs to be evaluated fully and diagnosed, so that the appropriate cause can be treated. This may not necessarily be MS, and certainly best to find out. ...Read more

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I asked earlier about MS and white matter disease. I have had an MRI (2) actually. Shows lesions. "stroke" in october. But wad told not a stroke?

I asked earlier about MS and white matter disease. I have had an MRI  (2) actually. Shows lesions. "stroke" in october. But wad told not a stroke?

Need to sort out: Regarding your specifics, would check images of both neck and head, and even consider lumbar puncture. MS patients can certainly have strokes, and my concern with you involves possibility of a very different disease than MS, such as anti-phospholipid antibody syndrome, arteritis, lupus, even sarcoidosis. Highly recommend opinion from university hospital neurology service. ...Read more

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What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more

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I had an MRI done an it says mild patchy white matter hyperintensity of the pons is stable likely representing microangiopathic disease mean what doe?

I had an MRI done an it says mild patchy white matter hyperintensity of the pons is stable likely representing microangiopathic disease mean what doe?

Small vessel disease: "microangiopathic" means "small vessel disease, " implying that you have some small blood vessel damage due to high blood pressure, diabetes, or high cholesterol ("hardening of the arteries"). This is your warning that chronic problems such as those (if you have any of them that you know of) need to be addressed. ...Read more

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MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?

Concern for MS, But: Phyllis, talk to the doctor who ordered the MRI, since he/she can interpret the MRI in the context of the symptoms that brought you to the clinic. In some cases, periventricular white matter lesions are the result of migraines, old head trauma, neuron migration issues, or MS. It is hard to know from just a description of the MRI which is the cause. Good Luck and Stay Healthy! ...Read more

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