Doctor insights on:
Which Vaccines Are Contraindicated In G6pd Deficiency
Which malignancies and/or granulomatous conditions are seen in individuals that only have IgG subclass 3 (igg3) deficiency?
Rare in USA: Common in the 3rd world leading mainly to corneal changes and diminution of vision. Usually in children who have diets restricted in vitamin a. Easily correct with teas made from vitamin a containing herbs found growing wild locally but hampered by ignorance and poor distribution of knowledge of this remedy. ...Read more
How is a thiamine or folate (folic acid) deficiency diagnosed? are there any cases where oral supplementation are inadequate?
Your doc can do: lab work to test for nutrient levels. A very good MicroNutrient Panel is done by Spectracell Lab in Texas. Peace and good health. Many multivitamins are weak. A nutritionist or natural doc can help guide you. ProThera is an excellent company but you need a doc to order the supplements for you there. ...Read more
IgM antibodies,,,: These are known as cold agglutinins because they agglutinate or act at colder temperatures than IgG or "warm" agglutinins. That is, they act or agglutinate at colder than body temperature or 28-31 deg Centigrade. This is mostly due to idiopathic or unknown cause, lymphoma type disease or infection. The result is hemolysis of the red cells and anemia with its symptoms. They're IgM antibodies. ...Read more
Dravet Syndrome & : Related scn1a mutations are genetic, not vaccine-induced. Fever from any cause can trigger seizures. . Genetic mutations are passed on or occur by accident when the germ cells ( egg & sperm) divide & 1/2 of the germ cell's chromosomes from each parent combine for the the genetic make-up of the child. See http://www.Omim.Org/entry/182389?Search=scn1a%20expression&highlight=expression%20scn1a. ...Read moreSee 1 more doctor answer
Are there any malaria medications that can be taken and considered safe for G6PD deficient patients?
Why are human endogenous retroviruses (herv's) "activated" in some people, but not in others, when exposed to exogenous viruses? Genetic mutations?
HERV's evolutionary: Endogenous retroviruses have made us evolve. They make up 8% of our dna genome. These aren't of the same class as HIV (lentivirus) or htlv (deltaretrovirus). Few are active & only w/growth & infection. Co-infection w/hiv can turn on herv replication wh/allows our immune system ability recognize & kill HIV viruses w/herv presenting-hiv infected cells leading to new therapies for HIV (vaccines!). ...Read moreSee 2 more doctor answers
Children / 3rd world: Common in the 3rd world leading mainly to corneal changes and diminution of vision. Usually in children who have diets restricted in vitamin a. Easily correct with teas made from vitamin a containing herbs found growing wild locally but hampered by ignorance and poor distribution of knowledge of this remedy. ...Read more
Vitamin A: So don't eat that polar bear liver raw (it contains mega-doses of vitamin a)! vitamin a doses greater than 100, 000 iu / day are well known to cause liver damage, and even 25, 000 iu at a time can be dangerous. Beyond that iron can damage the diseased liver (hap c, cirrhosis), and herbal supplements can sometimes contain liver toxins. And you thought valerian was good for you! ...Read more
I have an IgG subclass 3 deficiency. What diseases/disorders are associated with this? Are you more likely to acquire certain diseases/disorders?
IgG3 subclass def: Igg has four types. Igg3 is involved in fighting against carbohydrate covered infectious organisms. Igg1 is the most numerous and igg3 is of much less quantity. If you have normal antibody titers to vaccines, then you are likely safe. I would simply monitor all of your immunoglobulin levels yearly. ...Read more
Why are ACE inhibitors usually not the first line of drug therapy in newly diagnosed cases of hypertension among elderly (55+years)?
Are there diff versions of G6PD deficiency? If so how these differences are established? By blood test may be?
Genetic testing: G6pd is due to mutations in the gene. Like other genes there are multiple mutations that can produce the same end result. It is not a usual blood test by DNA analysis. You may consult this site for more details: https://ghr.nlm.nih.gov/condition/glucose-6-phosphate-dehydrogenase-deficiency ...Read more
Are there any vitamins/foods that are proven (or recommended) to boost/strengthen immune system in a person with immunodeficiency?
It depends: Western medical doctors typically look for a deficiency (such as Vit D) or conditions which impacts the immune system. Therapy is then directed accordingly. In Washington State Naturopaths might have some other ideas and if you have a good Chinese Medicine Herbalist nearby check them out. Hopefully, there are biomarkers which can be followed to better assure effective therapy. ...Read more
In countries that have some few polio cases , is having the IPV 5 doses considered enough or kids should take OPV too ?
Polio Vaccines: The OPV is a live vaccine and theoretically provides more protection than a full series of IPV. If there is an outbreak of polio, I would consider getting a dose of OPV, the incidence of getting polio from the OPV is miniscule but it is there just FYI. ...Read moreSee 1 more doctor answer
Why is it that alpha and beta -thalassemias result in more clinically severe diseases than other types of thalassemia?
Used for blood cells: Alpha globulin (made by the Alpha genes) and beta globulin (made by the beta genes) are the 2 globulin molecules needed to make normal adult hemoglobin (the red stuff in normal red blood cells). Mutations that prevent Alpha and beta globulin production will cause severe symptoms, but other mutations may not be as noticeable if the proteins the other genes make are not as crucial to life. ...Read moreSee 1 more doctor answer
Which is the safest form of Vitamin D for those with chronic liver disease? Borderline insufficiency,increased demand perhaps ? Not sure dX yet
A few: Pernicious anemia is a specific type of anemia caused by vitamin b-12 deficiency. This particular type of anemia is usually described as macrocytic or megaloblastic. Other causes of megaloblastic anemia include folate (folic acid) deficiency, certain genetic conditions, some medications, myelodysplastic syndromes (a form of bone marrow cancer). Consulting your physician or a hematologist is necessary. ...Read more
Can chronic exposure to toxins cause mctd? Two of us that worked together have mctd, cvid, autonomic disorders ..
Among all the types of hepatitis, which is the most severe form? Is it possible that a patient with hepatitis b will also have hepa c?
Depends: There are many types of hepatitis and all forms of can be fatal but fortunately most patients recover quite well. With respect to hepatitis c most patients go on to develop chronic hepatitis with ongoing liver damage. Hepatitis b is more common in southeast asia with most patients not going on to chronic hepatitis. Both forms can exist in the same person. Alcohol should not be consumed ...Read moreSee 1 more doctor answer