Doctor insights on:
Which Is The Neurotransmitter In The Brain That Makes Headache Pain To Develop
Plus or minus: Too much of a neurotransmitter such as glutamate may provoke headache but so too for thyroxine, norepinephrine, antidiuretic hormone, vasoactive intestinal peptide. Many times the problem isn't too much but too little (eg serotonin) or simply imbalances between several neurotransmitters. ...Read more
A neurotransmitter is a chemical messenger that carries, boosts and modulates signals between neurons and other cells in the body. In most cases, a neurotransmitter is released from the axon terminal after an action potential has reached the synapse. The neurotransmitter then crosses the synaptic gap to reach the receptor site of the ...Read more
If pristiq (desvenlafaxine) worked for 2 months beautifully (then stopped) what neurotransmitters does my brain need?
Worked for what?: Next treatment steps depend on why you were prescribed Pristiq (desvenlafaxine) in the first place -- and what it "worked for"? Please discuss with your own physician, who will want to know what's happening with you so s/he can improve your results. It may not be specific neurotransmitters at all, as these are not the sole explanation for difficulty you might be having. ...Read moreSee 1 more doctor answer
If psychiatric meds only change levels of neurotransmitters in brain, does everything go back to how it was before when the med is stopped or changed?
Very interesting ?: It is too general a question to answer, as each drug is different as is each patient's brain and illness. We assume things have re established an equilibrium if the person remains normal after the med is stopped ( ie a cure). If the illness returns quickly, then we assume that the medication was acting like a "cast" and was helping maintain but necessarily re establishing the equilibrium. If longterm side effects remain, such as a permanent dyskinesia then we know there has been a permanent change in brain chemistry.In reality however the brain is an ever-changing organ with great plasticity, so that the above comments can only be viewed as hypotheses and gross generalizations. ...Read moreSee 1 more doctor answer
ACH synthesis brain: Ach in the brain is produced from acetyl-coa (from glucose metabolism) & from choline, which is actively transported across blood-brain barrier. Most dietary choline comes from phosphatidyl choline (major phospholipid in membranes of plants&animals) acetyl-coa & choline are independently synthesized in neuron cell body & transported along axon to synapse where they are joined into acetylcholine. ...Read more
Not in the clinic: There are no tests available to measure brain neurotransmitter levels in the clinic. Researchers sometimes collect spinal fluid by a spinal tap, but this does not necessarily measure brain levels and it is not available to clinicians. There are some imaging tests that can give approximate numbers, but these are research studies and not used in clinical medicine. ...Read more
Suggest: Contact either a psychiatrist or neurologist and see if that is a fit for you. ...Read more
Unknown for sure: There is a great deal of research in neurobiology about how the neurotransmitters' changes translate in the brain into thoughts and feelings, normal or abnormal. There are theories but no consensus yet. Perhaps my colleagues could add their views. But clinically, these connections have been clearly observed and symptoms like delusions can vastly improve with medications working at this level. ...Read more
GABA receptor: Like many ligands, gaba binds to its specific receptor, the gaba receptor (with several subtypes). Depending on the location of the gaba receptor, binding of gaba modulates various signaling pathways in the body. Note that gaba receptors are also found in organs outside of the brain. ...Read more
The medical term is cephalalgia. It is a feeling of pain that can occur on either both sides or just one side of the head or neck. Headaches can be sharp, dull, or throbbing, and can radiate to different areas of the head. They typically last less than an hour but can ...Read more
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