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Doctor insights on: Which Is Better Wellbutrin Or Lexapro For Help With Anxiety

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I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

Drug Interactions: Elavil (amitriptyline) + Wellbutrin (bupropion) ^ es seizure risk. Escitalopram +amitriptyline ^'es risk of serotonin syndrome. Wellbutrin + Lexapro ^es seizure risk. I am assuming that the Elavil is added in for insomnia or pain control and not for depression/ anxiety. This does not mean that these drugs can't be used together but there are possible drug interactions. D/W your physician. ...Read more

Dr. Heidi Fowler
3,299 Doctors shared insights

Anxiety (Definition)

Anxiety is a general term for several disorders that cause nervousness, fear, apprehension, and worrying. These disorders affect how we feel and behave, and they can manifest real physical symptoms. Mild anxiety is vague and unsettling, while severe anxiety can be extremely debilitating, having a serious ...Read more


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I have been on wellbutrin 150xl for 5 weeks and clonazepam as needed. Anxiety is still bad. My pdoc wants to add lexapro 10mg. Is this common?

I have been on wellbutrin 150xl for 5 weeks and clonazepam as needed. Anxiety is still bad. My pdoc wants to add lexapro 10mg. Is this common?

Yes: You are balancing the chemicals in the brain that when out of balance cause this anxiety. I hope you are also getting psychological counseling to address non medication approaches to address this as well, so you can avoid the panic which often accompanies your condition. ...Read more

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Which antidepressant would you recommend for anxiety Lexapro or wellbutrin (bupropion)?

Which antidepressant would you recommend for anxiety Lexapro or wellbutrin (bupropion)?

Anxiety medication: Lexapro and other ssri medications are considered first line treatment for a variety of anxiety disorders. Wellbutrin, (bupropion) while often a very effective medication for depression (and off-label for add/adhd), does not have a significant serotonin effect and therefore is not considered to be a great medication to treat anxiety. It does help with depression that can be co-morbid commonly with anxiety. ...Read more

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On Lexapro. I feel very sluggish and unmotivated. I have anxiety so would it still be okay to ask my PCP for Wellbutrin (bupropion)?

How long have you: Been on the Lexapo for? Have you given it an adequate trial and time to see if this possible side effect resolves. Wellbutrin (bupropion) is primarily for atypical depressive disorders. Lexpro and wellbutrin (bupropion) can be used together for anxiety & depression or mixed depressions. Ask you pcp or psychiatrist about optimizing your meds. ...Read more

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Is lexapro and Wellbutrin (bupropion) a good combination for post partum anxiety and depression?

Is lexapro and Wellbutrin (bupropion) a good combination for post partum anxiety and depression?

Discuss w/ OBGYN, etc: Less is best if you are breastfeeding and if one works it may be better than a mix, but ask your pediatrician and OBGYN and psychiatrist if you have one. Please consider good psychotherapy since it's a big help to make these months easier - new mother support is very important! It might even make drugs less needed. Best wishes! ...Read more

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Severe health anxiety and depression. CBT and Wellbutrin (bupropion) and Lexapro not working. Can't sleep, can't stop worrying. What can I do? Life stinks.

Severe health anxiety and depression. CBT and Wellbutrin (bupropion) and Lexapro not working. Can't sleep, can't stop worrying. What can I do? Life stinks.

Regulation of habits: Besides the CBT, Wellbutrin (bupropion) & Lexapro try a notebook or tablet to track your daily routines like diet, sleep, regular meals, 7-9, 11-1, 5-7, enough sleep, exercise, dietary intake (calories), meditation, relaxation exercises, tai-chi, martial arts, prayer, anything that will help light up the frontal lobes if we would scan yours. It will take some time but all of the above will work over time. ...Read more

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Is there any supplements to help a male experiencing no sex drive on 10mg Lexapro and 150mg wellbutrin (bupropion) XL for ocd/anxiety?

Is there any supplements to help a male experiencing no sex drive on 10mg Lexapro and 150mg wellbutrin (bupropion) XL for ocd/anxiety?

Female sex cream: Apricus biosciences is currently developing the product femprox, a topical cream for the treatment of female sexual arousal disorder. It contains prostaglandin e1 as the active ingredient and a permeation enhancer ddaip which facilitates the delivery of the drug into the blood stream. An existing drug, bremelanotide, has also been found to increase libido in 90% of subjects. ...Read more

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44M. Takes Lexapro for depression. What else can he take for anxiety? Wellbutrin (bupropion)? Needs to be able to take during the day. Hates job, stressed.

44M. Takes Lexapro for depression. What else can he take for anxiety? Wellbutrin (bupropion)? Needs to be able to take during the day. Hates job, stressed.

Many options: Lexapro is usually good for both depression and anxiety. Standard dose is 20 mg. Could increase dose if on less than that. Adding Wellbutrin could help depression, but can increase anxiety for some people. Buspirone could be adding if anxiety persists despite adequate treatment of depression. Consider switch from lexapro to paroxetine, effexor, (venlafaxine) or mirtazepine before going to polypharmacy ...Read more

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I have had severe anxiety/panic for years. I have taken prozac, zoloft, wellbutrin, lexapro, and now viibryd (vilazodone hydrochloride). Nothing seems to work. What should I do?

Try counseling: While some medications will not work there are meds that will but along with counseling as well. Anxiety and depression are best treated with both behavior modification and medication. Give it some thought and discuss with your provider. ...Read more

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I am taking 20 m Lexapro and 150 welbutrin with back up Xanax (alprazolam) for panic/anxiety. I'm still feeling lousy. Should I see a psychiatrist to manage meds?

Yes: Psychiatrists are specially trained to deal with complex anxiety problems. You can receive a good review of your case, with individualized treatment recommendations. Since you're still not feeling well despite multiple medications, it's time to seek specialty care. Please realize, though, that psychotherapy for your anxiety will also increase treatment effectiveness. ...Read more

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I take 150 of bupropion 2x daily and 20mg of lexapro (escitalopram). prescription by primary. My anxiety has improved, but I'm really forgetful. Feedback?

I take 150 of bupropion 2x daily and 20mg of lexapro (escitalopram). prescription by primary. My anxiety has improved, but I'm really forgetful. Feedback?

Yes. Be checked for: Other causes of forgetfulness. These could include B12 and folate deficiencies, low free t3 (liothyronine) or low t4, lyme's disease, anemia, and a whole host of other possibilities. If nothing else is found, your dr may wish to lower down one or the other antidepressants. If you supplement with b12, use the form called methylcobamine, and if you supplement folate, use l- methyl folate instead of folic acid. ...Read more

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I've taken 20 mg of Lexapro (escitalopram) for 15 months for general anxiety. In June I was prescribed bupropion 2xday for weightloss. I want to wean off both. How?

Agree: Definitely discuss with your MD how best to do this. If different doctors are prescribing the medications then you need to make sure that they communicate. Both should not be stopped abruptly. Both can be safely tapered over several weeks. You might want to taper one at a time so that if your mood changes you know what caused it. ...Read more

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Was on wellbutril XL for yrs and switched to viibryd (vilazodone hydrochloride). Felt great depression/anxiety wise but noticed rapid weight gain; same with lexapro. Options?

Was on wellbutril XL for yrs and switched to viibryd (vilazodone hydrochloride). Felt great depression/anxiety wise but noticed rapid weight gain; same with lexapro. Options?

Your choice: Wellbutrin does not have weight gain associated but works differently than viibryd (vilazodone hydrochloride). If the viibryd (vilazodone hydrochloride) is working well for you, then try to fight the weight gain with regular exercise and reduction of your portion sizes. ...Read more

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Which antidepressant does not affect libido besides Welbutrin n also helps w anxiety 2 repla lexapro? On Lexapro 10mg, Welbutrin 500mg, n Buspar (buspirone) 30mg

Which antidepressant does not affect libido besides Welbutrin n also helps w anxiety 2 repla lexapro? On Lexapro 10mg, Welbutrin 500mg, n Buspar (buspirone) 30mg

Consult doctor: Almost all antidepressants can affect libido. Talk with your doctor about this. It is possible that another SSRI will work well and not produce this result. There are also other classes of antidepressant medication. ...Read more

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28yo fem w/ depression, anxiety. Zoloft for ~10 yrs, 50mg then 75. Added welbutrin. Zoloft quit helping, tried lexapro (escitalopram). Big weight gain. Rec new drug?

Antidepressants best: Another antidepressant, possibly snri like Effexor (venlafaxine) may be more helpful at this time. Add ons such as gaba- calm and natural anxiety aids can help. They do cause weight gain usually. Therapy is always an important treatment modality for depression and anxiety, don't think it is not helpful! ...Read more

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Fiance has performance anxiety = no sex drive, yet sex dreams. Ocd type o, had exposure therapy and and is on Lexapro (escitalopram) and wellbutin. Any ideas?

Fiance has performance anxiety = no sex drive, yet sex dreams. Ocd type o, had exposure therapy and and is on Lexapro (escitalopram) and wellbutin. Any ideas?

I think that he has: To be motivated enough to ask this question for himself. It is fine that you are asking. He has had exposure therapy - has he done cognitive behavioral therapy? This can be an excellent form of treatment. Take care. ...Read more

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Does wellbutrin (bupropion) have fewer side effects than lexapro?

Different: Wellbutrin (bupropion) does not cause weight gain and it does not have sexual side effects. It does carry a small but increased risk for seizures and may be more likely to make anxiety worse among other side effects. ...Read more

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What're the differences between Lexapro and wellbutrin (bupropion)?

What're the differences between Lexapro and wellbutrin (bupropion)?

Differences: Lexapro is a serotonin specific reuptake inhibitor. Wellbutrin (bupropion) is a norepinephrine-dopamine reuptake inhibitor. While both are antidepressants, ssris tend to be better for anxiety conditions than wellbutrin (bupropion). Wellbutrin (bupropion) is more effective for comorbid substance use disorders. Wellbutrin (bupropion) is very weight friendly, does not tend to impair sexual function, but has a somewhat higher seizure risk. ...Read more

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Side effects of Lexapro wellbutrin and Xanax (alprazolam) together?

Low probability: There are the possibility of low probability side effects. With respect to specific interactions, the most prominent thing to remember is that if you stop taking your xanax (alprazolam) suddenly while taking wellbutrin and Lexapro you may make it more likely that you would have a seizure. You also may find operating a motor vehicle more challenging when taking xanax (alprazolam) with any medications. ...Read more

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I am currently on Wellbutrin (bupropion) XL and Lexapro and was prescribed Tramadol. Wanted to see if there was a bad interaction if taken together?

I am currently on Wellbutrin (bupropion) XL and Lexapro and was prescribed Tramadol. Wanted to see if there was a bad interaction if taken together?

Requires Tact: Combination of SSRI such as Lexapro can apparently cause serotonin syndrome. In addition, the manufacturer of tramadol notes concomitant therapy with SSRI increases risk of seizures. Furthermore, both Tramadol and Wellbutrin (bupropion) can lower the seizure threshold. PGT testing to determine CYP2D6 status may be able to guide treatment. The prescribing physician (s) should be informed of this combination. ...Read more

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Can oxycodone be taken if lexapro and Wellbutrin (bupropion) are being taken daily?

Medications: There is always a risk of adverse effect when combining medications. That risk is increased with narcotic pain medications (like Oxycodone) and mood disorder medications such as lexapro and wellbutrin (bupropion). It is very important to fully disclose all your medications to your physician. I would recommend contacting your prescribing physician for further instructions. ...Read more

Dr. Alan Ali
792 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more