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Doctor insights on: Which Is Better For Autoimmune Disorders Humira Or Enbrel

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Are there other alternatives to enbrel (etanercept) and humira?

Are there other alternatives to enbrel (etanercept) and humira?

Yes: It depends on the disease being treated. For psoriasis (my field is dermatology), there is infliximab (remicade), ustekinemab (stelara), alefacept (amevive) - not used much now and golimumab (simponi) - not used much either. ...Read more

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Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


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I was on humira and felt terrible, is enbrel (etanercept) any better?

It's different: Different people react differently to different medications. It is possible that you will have the same trouble with Enbrel (etanercept) but it's also possible that you will have no trouble with enbrel (etanercept). The only way to know for certain is to try it. ...Read more

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What is the difference in mechanism or humira and enbrel (etanercept)?

None: There both basically work by the same mechanism which is inhibition of tnp. ...Read more

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Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more

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What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? Do all patients develop immunity?

See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomena. ...Read more

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Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! both should be tried only after Methotrexate therapy has failed! ...Read more

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On actemra (tocilizumab) IV(dose increase in dec)and methotrexate for 5 mon now but still having bad flare ups. Tried humira,enbrel,etc. since diagnosis in Dec 2013?

Your question is?: Your have not asked a question. This issue needs to be discussed with your rheumatologist. No one can give you specific advice over the internet without a complete history and exam. ...Read more

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With other tnf inhibitors such as humira and enbrel (etanercept) are there?

See below: Cimzia (certolizumab pegol), simponi (golimumab), and Remicade (infliximab) are the other tnf Alpha inhibitors available in the United States. ...Read more

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What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more

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Dr. Tania Dempsey
90 doctors shared insights

Autoimmune Conditions (Definition)

The body is reacting to something that is indigenous to itself. It is acting as if it is a foreign invader , and 'fighting" it. This is not ...Read more


Dr. Robert Lowe
121 doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more