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Doctor insights on: Where Does Coronary Artery Disease Originate

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Where does coronary artery disease originate?

Where does coronary artery disease originate?

CAD: Coronary artery disease, just as disease in other arteries, is the result of a long time process initiated by: 1. Genetic pre-disposition 2. Uncontrolled/untreated high blood pressure, diabetes, cholesterol/triglycerides 3. Smoking, obesity, lack of exercise, stress. ...Read more

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Dr. Rick Koch
2,465 doctors shared insights

Coronary Artery Disease (Definition)

Coronary artery disease is the leading cause of death and disability in adults in the U.S. It develops when lipid (fatty) plaques builds up in the arteries. Eventually, the plaque can occlude the artery, thereby stopping blood flow to the organ supplied by that artery. If the artery supplies the heart, blockage causes a heart attack. If the blockage is in a brain vessel, the ...Read more


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How does coronary artery disease develop in the body?

How does coronary artery disease develop in the body?

Slowly: Low density lipoprotein (ldl) is taken up by endothelial cells in blood vessels. The LDL is broken down (oxidized) and absorbed by macrophages within the wall of the blood vessel. Ultimately, the macrophage which is full of oxidized LDL will die. The dead cells and cholesterol accumulate in the wall of the artery interfering with the flow of blood. ...Read more

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How does coronary artery disease affect someone's body?

Symptoms/lifespan: Coronary artery disease affects the quality of life and the length of life. Quality of life is affected by reduced functional capacity (ability to do things), chest pain, shortness of breath, loss of employment, and hospitalization. Length of life is reduced as a result of sudden death and myocardial infarction. ...Read more

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How does coronary artery disease disrupt homeostasis?

How does coronary artery disease disrupt homeostasis?

Can weaken the heart: If the blockage results in a heart attack, the heart muscle can get damaged and not contract as hard. That would definitely disrupt homeostasis. ...Read more

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How does coronary artery disease lead to myocardial ischemia?

How does coronary artery disease lead to myocardial ischemia?

By blocking the flow: In young, healthy individuals the inner lining of the blood vessels is clean and smooth. Overtime, for many reasons, the inner surface of the heart blood vessels (coronary arteries) may start becoming bumpy/lumpy or blocked due to fat (cholesterol) deposits called "atherosclerotic plaque". This in turn reduces the amount of blood flow available causing "ischemia" (oxygen deprivation). ...Read more

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Does coronary artery disease always cause shortness of breath?

Yes: Coronary artery disease, angina, and heart attack are a continuum of a process. With these congestion f the lungs can occur, or blood clots can embolize, or cardiac output can be reduced. All affect oxygen delivery and feeling of shortness of breath. ...Read more

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Does coronary artery disease directly cause ventricular tachycardia or is it after heart attacks and damage etc?

Does coronary artery disease directly cause ventricular tachycardia or is it after heart attacks and damage etc?

Both: Myocardial infarction (heart attack) and scarring of the heart can lead to arrhythmias. Also, if coronary artery disease (CAD) causes impairment in flow of blood, ischemia may lead to arrhythmias. However, not all arrhythmias are due to CAD or mi. ...Read more

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What's coronary artery disease?

What's coronary artery disease?

CAD: Coronary artery disease is defined as obstructive lesions in the coronary arteries that supply the heart muscle . These start as areas of inflammation that progress into obstructions and affect the different layers of the blood vessel wall (from inside out). ...Read more

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What is coronary artery disease?

Cholesterol plaquing: Cholesterol plaquing of the coronary arteries.

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Dr. Patricia Foster
1 doctor shared a insight

Artery (Definition)

Arteries are a type of blood vessels. We can divide blood vessels into 2 categories. Arteries are high pressure vessels which deliver (red) oxygen + blood out into the body. Veins on the other hand or low pressure vessels which return (dark) oxygent - blood from the body ...Read more


Dr. Amrita Dosanjh
2 doctors shared insights

Coronary Artery (Definition)

Coronary artery is the name given to the blood vessels that supply the myocardium. The word coronary was coined by the first anatomists that noticed that if you remove all muscle from the heart the remaining vessels resemble the shape of a corona or crown. ...Read more