Doctor insights on:
When Does Lupron Wear Off
After Lupron (leuprolide): A 3.75 lupron (leuprolide) depot dose well generally take a while to wear off. After 4 weeks, the dose should be gone and your would start growing a follicle for the next cycle, if you have regular cycles. Expect a subsequent period about 6-8 weeks after the last injection. The hot flashes usually subside about 4-6 weeks after the last injection. The more doses you have receive, the longer it may take. ...Read more
Varies: There are three forms of lupron, (leuprolide) one is a subcutaneous injection daily which will wear off very quickly. The second type is a depot form which last for approximately 30 days in the body, and lastly there is a 90 day form. A woman will usually ovulate 2 to 4 weeks after the effects of the Lupron (leuprolide) has worn off. ...Read more
Usually: Within 1 cycle or 1 month. Good wishes. ...Read more
How long till 11.25mg lupron (leuprolide) wears off? I don't feel symptoms from it last shot was sept my husband & I want ttc should we wait? If so, how long ttc?
3 months: The shot lasts 3 months. It can have some effects a little longer. You don't have to wait at all. There is no danger in becoming pregnant but you may not ovulate. ...Read more
Hormone inhibitor: Lupron (aka leuprolide) inhibits the production of testosterone and estrogen from the testes and ovaries, respectively. It is used in the treatment of a number of things including endometriosis, prostate and breast cancer and inappropriately early puberty in kiddos, each of which is made worse by excessive testosterone or estrogen secretion. ...Read more
Menopausal effects: Lupron (leuprolide) injections are used for many reasons in gynecology, most commonly in the treatment of fibroids and endometriosis. Essentially, Lupron (leuprolide) shuts down ovarian function and leads to a menopausal state. Therefore, side effects include hot flashes, vaginal dryness, mood swings, decreased libido, and bone loss. ...Read more
Depends/ indications: I agree with the prior answer in context, but want to weigh in on other uses. Studies show Lupron (leuprolide) in the depot form is effective at shrinking fibroid volume by about 1/3 in 3 months. This gives a proven statistically lower blood loss in women preparing for surgical myomectomy. Also Lupron (leuprolide) in the non-depot form is safe, effective and routinely used in stimulations for ivf. ...Read more
Lupron is a powerful suppressor of estrogen activity (mediated through the hypothalamus and pituitary), and it is used to suppress symptoms of endometriosis. It has many side effects including hot flashes and bone loss.
Many doctors use this but I do not. It is my professional opinion (and profession) that women with endometriosis would benefit more from expert excision of their disease. ...Read more
No time limit: It really depends upon its benefit to your husband. Men with metastatic disease can have long term benefit. ...Read more
By far, the most common side effect is hot flashes, because Lupron (leuprolide) causes a temporary menopause. Poor sleep resulting in emotional side effects or head ache are also common. A serious effect from long-term Lupron (leuprolide) is osteoporosis. Many of these side effects are reduced or eliminated with extra "add-back" hormones.
Some women have no side effects at all. ...Read more
Terrible: Lupron (leuprolide) causes reversible menopause. So as soon as the medicine takes effect the estrogen drops to zero same as complete menopause. Hot flashes, night sweats, moods, memory issues and joint pain etc. Many dr. S use this for endometriosis but endo is a surgically treated disease. Lupron (leuprolide) only temporarily diminishes symptoms but makes people miserable. Excisional surgery is needed via laparoscopy! ...Read more
Lupron for what?: Need more information. For what problem are you on Lupron? What symptoms are you having that are not going away on Lupron. Best wishes! ...Read more
Endometriosis. ..: Depo-lupron monthly or 3-month injections are used for women with endometriosis or chronic pelvic pain, men with prostate cancer, and children with puberty too young. It may be used to shrink uterine fibroids before surgery. Depo-lupron is used in fertility treatment to prevent ovulation in frozen embryo transfer cycles & egg donor recipients, and can be used before ivf in women with endometriosis. ...Read more
Assume Pelvic Pain: ? Diagnosis endometriosis and pain. If Lupron (leuprolide) is not helping, the pain is either coming from very severe endo, or from another source. A common associated pain is from the inguinal region and is often associated with endo. Surgery to correct this relieves pain in more than 80%. There are other potential causes of pain that should be evaluated. Seek pelvic pain/endo specialist for more help. ...Read more
1 or 3 months: Lupron (leuprolide) comes in 1 or 3 month doses (3.75 or 11.25 mg) and these injections usually cause menopause symptoms which I've seen as both mild or severe. It rarely continues beyond the treatment period & is a good way to pre-treat or reverse endometriosis or to shrink fibroid tumors prior to surgery. Discuss with your doc if your symptoms are severe or if you need estrogen to counter the severe effects. ...Read more
Terrible: Hate the drug. It has bad side effects and very few indications in my opinion. If it's given for endometriosis or pain, there are other treatments. The most effective treatment of endo is surgical excision. This can cure the disease but there are few providers capable of this procedure. Recurrent pain after surgery needs to be addressed but Lupron (leuprolide) is not the answer. Ther are a few indication. ...Read more
Can be: Depending on why you are taking lupron, (leuprolide) it takes a month to suppress your cycle. Did you take the 3 month dose? Why are you taking it? Did you have abnormal bleeding before the injection. Talk with your doctor who ordered it and ask if you have any other issues that need to be addressed. ...Read more
Lupron: 20F notes: My partner started monthly shots of Lupron yesterday. Is it safe for us to be intimate? ANS: please define partner, intimate and safe. Do you mean will you not get pregnant if partner is male? Or safe for you or for your partner. Does intimate mean hugging, or kissing or having intercourse? Would also be important to know reasons for Lupron. Get back with us. ...Read more
How long after stopping lupron (leuprolide) for endometriosis will it take for your body to go back to normal?
Few days: Even though half life of Lupron (leuprolide) is only 3 to 4 hrs plasama levels will remain high for few more days (missing one dose is not a big problem). ...Read more
What are the long term effects of lupron (leuprolide)? Why are so many women asking to have it taken off the market?
I'm 22 started lupron (leuprolide) depo. No appetite and craving chocolate. I don't even like chocolate but I suddenly need dark chocolate. Weird?
Possible: Lupron (leuprolide) causes hormonal changes so craving for chocolate is not weird in your case. ...Read more
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