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Doctor insights on: When Does Humira Start Working

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Humira (adalimumab) every 2 weeks stopped working&got a bad psoriasis flare-up...Now on humira (adalimumab) weekly w/15mg methotrexate but still have bad psoriasis.U recommend?

Humira (adalimumab) every 2 weeks stopped working&got a bad psoriasis flare-up...Now on humira (adalimumab) weekly w/15mg methotrexate but still have bad psoriasis.U recommend?

Psoriasis: While Humira is an excellent therapy for severe psoriasis, there are times when it stops working. Another option for you may be stelara (ustekinumab) which is also an injectable treatment which works a little differently than does Humira and is extremely effective in many patients. ...Read more

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Dr. Robert Lowe
169 doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more


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Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte.Do u think psorias will clear?Y did humira (adalimumab) stop working?Stress overpower it?

Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte.Do u think psorias will clear?Y did humira (adalimumab) stop working?Stress overpower it?

Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more

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Hello, I have psoriatic arthritis my side's hurt. Below my. Shoulders. The humira (adalimumab) i'm talking isn't working as well this time how to stop the pai?

Work closely with Dr: If you have spinal involvement from your psa you may require physical therapy and additional medication to control the symptoms. If Humira (adalimumab) alone is not effective the addition of Methotrexate may help control the disease. If you are already taking Methotrexate you may need to change to a different injectable medication. Remember these medications may take 3 months to reach peak effect. ...Read more

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Humira and Methotrexate are not working for my psoriasis. I asked the doctor about Stelara (ustekinumab).  Dr. hasn't seen good results w/other patients on Stelera so doesn't use it. What would you recommend?

STELERA/HUMIRA/METHT: Well if you have no improvement with Humira (adalimumab) and methtrexate, than there is no harm in trying stelera.Discuss with your doctor that it is not working, so what is the harm in trying if stelera will work for you otherwise you can get a second opinion from another dermatologist. ...Read more

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What is humira (adalimumab) for?

What is humira (adalimumab) for?

Too treat severe....: Rheumatoid arthritis, psoriatic arthritis. Ankylosing spondylitis and crohn's disease. I have used it off label in treating temporal arteritis and a few other conditions. However, off label uses are generally not covered by insurance. ...Read more

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What exactly is a humira (adalimumab) injection?

Usually not an issue: Most patient have little injection site discomfort. It is the only true human tnf-alpha antibody, and is given once every two weeks for arthritis, and once weekly for crohn's. I have had more success with this biologic than any other. ...Read more

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How long does it take for humira (adalimumab) to work?

See details: It may start to work after 1 or 2 injections but it usually takes 3-4 months to reach its maximum effectiveness. ...Read more

Dr. Robert Lowe
184 doctors shared insights

Humira (Definition)

Humira is an arthritis therapy which is a ...Read more