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Doctor insights on: When Do I Decide That It Is Time For Remicade For Ulcerative Colitis

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When do I decide that it is time for remicade (infliximab) for ulcerative colitis?

When do I decide that it is time for remicade (infliximab) for ulcerative colitis?

When it's bad enough: See your GI doc. Remicade (infliximab) recently ok'd for uc, as well as crohn's. Like steroids, can put people in remission quickly; unlike steroids can maintain it. If Mesalamine orally and rectally don't work, if immuno-suppressives like 6-meraptopurine or azathioprine don't work; if need to stay on steroids, or repeatedly go on steroids, or severe sx, consider remicade, (infliximab) cyclosporin, or even surgery. ...Read more

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Dr. Jonah Essers
541 doctors shared insights

Ulcerative Colitis (Definition)

An inflammatory bowel disease (IBD) that causes long-lasting inflammation in part of your digestive tract. Ulcerative colitis usually affects only the innermost lining of your large intestine (colon) and rectum.There's no known cure for ulcerative colitis, but therapies are available that may dramatically reduce ...Read more


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How should I decide when it is time to have continent ileostomy, especially if colitis is controlled?

How should I decide when it is time to have continent ileostomy, especially if colitis is controlled?

Based on symptoms: If your disease is controlled on medications then surgery may never be necessary. In most cases surgery is not ever needed. ...Read more

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Is methotrexate a typical treatment for sjogrens? I don't want have to take it, but if it will help i will...

Is methotrexate a typical treatment for sjogrens? I don't want have to take it, but if it will help i will...

Soon: We may have more specific treatments for ss, for now, if Plaquenil (hydroxychloroquine) has not worked, mtx may be a reasonable option. We only use low doses as compared to cancer tx, so side effects are much less. ...Read more

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If "imuran" fail to help a patient that has ulcerative colitis , so, what is the next plan for treating , is it coloctomy ?

Other drugs: If you are failing imuran (azathioprine), (azathioprine) there are several possibilities. (a) you can have your levels checked. Perhaps you need to go up on the imuran (azathioprine). (b) switch to Methotrexate (c) try Infliximab or adalimumab. Depending on where you uc is located, you might be a candidate for Mesalamine enemas, but that would only be valuable if you only have left-sided disease. ...Read more

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I am seeing a GI dr but just would like more feedback on how long it is safe to stay on 40mg of prednisone for severe ulcerative colitis?

I am seeing a GI dr but just would like more feedback on how long it is safe to stay on 40mg of prednisone for severe ulcerative colitis?

Quicker the better: Treatment of uc with Prednisone is challenging. Prednisone 40 is a solid dose. There is no definite "safe amount of time." prednisone's side effects affect the body slowly, so i would say one month would be completely ok and then the longer you stay on such a dose, the more side effects (bloating, irritability, fluid retention, etc) you will have. Work with GI to limit use of predniosone. G.Luck. ...Read more

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How common is it to use both methotrexate and hydroxychloroquine in treating juvenile arthritis? Is this safe? What should I know before starting?

How common is it to use both  methotrexate and hydroxychloroquine in treating juvenile arthritis? Is this safe? What should I know before starting?

JiA treatment: For multi-drug therapy for jia, Methotrexate is more commonly paired with biologic medication. For methotrexate, watch for mouth sores and nausea. Blood testing will be needed to check blood counts and liver tests. For treatment with plaquenil, (hydroxychloroquine) plan to have annual eye exams. ...Read more

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I take miralax (polyethylene glycol) sometimes, and i was wondering what can I do when it is time for a colonoscopy, for people who are used to stool softeners?

I take miralax (polyethylene glycol) sometimes, and i was wondering what can I do when it is time for a colonoscopy, for people who are used to stool softeners?

Best to : Discuss this with your GI doctor or colon and rectal surgeon who will be performing the procedure. Try drinking less caffeine and more fluid to 80 ounces per day or more and you will probably not need the MiraLAX (polyethylene glycol) any longer. ...Read more

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If I have beginning stages of chrons will it show on any tests or procedures. Is it possible to have chrons and it not show? It would explain a lot

If I have beginning stages of chrons will it show on any tests or procedures. Is it possible to have chrons and it not show? It would explain a lot

Crohn's: This condition can show up on blood testing and on colonoscopy, endoscopy, or small bowel capsule endoscopy. By the time you are having symptoms it is usually not hard to find if you look for it. The diagnosis can be difficult in a small number of people so you have to work with your doctor in that case and sometimes try treatments to see if you improve assuming inflammatory bowel disease. ...Read more

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I have on and off stomach issues. If it was ulcerative colitis or crohn's, would it come and go? Or does it only go away if you receive treatment?

I have on and off stomach issues. If it was ulcerative colitis or crohn's, would it come and go? Or does it only go away if you receive treatment?

IBD: Inflammatory bowel diseases (Crohn's and UC) typically do not have symptoms that "come and go", however, they can. Warning signs for these 2 disease are persistent diarrhea, weight loss, severe abdominal pain, bloody or mucous stools, vomiting, joint pain, and rashes. If your symptoms are severe OR have lasted longer than 2 months you should see a gastroenterologist. ...Read more

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I have been in remision from ulcerative colitis. If i want to take a nsaid aka motrin is it okay or will this cause a flare up? Which nsaids are safe?

I have been in remision from ulcerative colitis. If i want to take a nsaid aka motrin is it okay or will this cause a flare up? Which nsaids are safe?

Likely flare: Nsaid's are well know to flare uc. Check with your GI doctor. Some people can get away with limited amounts occasionally. ...Read more

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Is it possible for ulcerative colitis to be so mild that you dont need treatment? Just dietary modification?

Is it possible for ulcerative colitis to be so mild that you dont need treatment? Just dietary modification?

Yes: UC comes in a variety of places and penetrations. Hopefully you have a limited spectrum. You should have regular evaluations by a GI specialist even if you have mild disease. ...Read more

Dr. Scott Bolhack
2,089 doctors shared insights

Ulcer (Definition)

An ulcer is a discontinuity or a break in a body membrane that impedes the normal functioning of the organ of which that membrane is a part. Ulcers are further classified by their location. Ulcers are usually caused by infections, excessive acid production, stress, ...Read more


Dr. Eric Kaplan
1,012 doctors shared insights

Colitis (Definition)

Inflammation or infection of ...Read more