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When Can Holoprosencephaly Be Detected On Ultrasound
Yes: It can be detected during the pregnancy, but by the mean of the obstetrical ultrasonography and depends on the skills of the technician performing the procedure. The other screening tests performed during pregnancy, may predict some of the chromosomal disorders, associated with holoprosencephaly, such as trisomy 13. ...Read moreSee 1 more doctor answer
The sonogram is a test that looks at body organs with no radiation. It uses sound waves and can give us a 2 dimensional view of organs such as the kidney, liver, heart, and lungs. It can define spaces that are either solid or full of fluid. I can also guide large needles into an organ or near the spine, and can help define the area being cut open. Its a ...Read more
Undivided brain: Most of us have 2 halves in our brain, known as "hemispheres". Holoprosencephaly (HPE) is abnormal division of the embryo's brain and lack of separation of the cerebral hemispheres. HPI can be mild to severe and can cause defects in the development of the face and in brain structure and function. ...Read more
Lobar Holopreosenceh: I believe you are referring to Lobar Holopreosencehaly in which the brain is not formed well leading to severe mental retardation. This is a rare condition from failure of the brain to completely divide into two separate halves. Many parts of the entire brain may be fused and not allow normal function. This may be as a result of some chromosomal disorders. A more complete descriptionfromgeneticist ...Read more
Undetermined: Potential depends on the severity of the defect and associated features. Many die before birth and most have a brief existence.The defect involves a great range from very major to minor, with longevity matching the degree of defect. See www.ninds.nih.gov/disorders/holoprosencephaly for more information ...Read more
Brain Development: When the embryo's forebrain does not divide to form bilateral cerebral hemispheres (the left and right halves of the brain), it causes defects in the development of the face and in brain structure and function. In less severe cases, babies are born with normal or near-normal brain development and facial deformities that may affect the eyes, nose, and upper lip.The condition can be mild or severe. ...Read more
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