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Doctor insights on: Whats The Difference Between Wellbutrin And Celexa

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What's the difference between celexa and wellbutrin (bupropion)?

What's the difference between celexa and wellbutrin (bupropion)?

Mechanism of action: Celexa (citalopram ) is a antidepressant that works mainly on the serotonin metabolism wellbutrin (bupropion) works in the dopaminergic circuit . They can be combined for added effect or decrease of side effects of serotonin related antidepressants such as decresed libido. ...Read more

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Dr. Alan Ali
882 doctors shared insights

Citalopram (Definition)

Citalopram is a ssri medication used to treat anxiety and depression disorders, it's also used to treat ptsd and ocd. It takes 4 to 6 weeks to be fully effective. Side effects; sedation, minor temporary stomach issues, delayed orgasm in males and rarely weight gain. It is ...Read more


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Can celexa 40 mg and wellbutrin (bupropion) 150 be taken together?

Combination of meds: Yes, they can. However, it's best to reduce the dose of citalopram to 20mg. citalopram and wellbutrin (bupropion) are in different classes thus they have different mechanisms of action. You can liken it to cream AND sugar in your coffee. ok with one or the other but maybe better with both. I do not recommend taking Phentermine under any circumstances. pls make sure to discuss all of this with your provider. ...Read more

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I have Cymbalta, (duloxetine) Wellbutrin and celexa combo. Is it harmful? fibro and depression

I have Cymbalta, (duloxetine) Wellbutrin and celexa combo. Is it harmful?  fibro and depression

I'd be concerned: Definitely discuss the combination w/ your Dr - ALL three are risky in combo w/ the others. On top of serotonin syndrome, the Wellbutrin (bupropion) in combo can cause seizures and other bad things. If needed, the risk may be necessary but if there are options, this is not a good one. Ask yourself, are you satisfied? A therapist might help you think it through. ...Read more

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Tried celexa, made anxiety worse, sister tried it, same reaction. She had success w/ wellbutrin (bupropion) said it works differently, could this help me?

Tried celexa, made anxiety worse, sister tried it, same reaction. She had success w/ wellbutrin (bupropion) said it works differently, could this help me?

NO: Usually people with anxiety D/O's are more sensitive to side effects. Antidepressants that modulate anxiety (Wellbutrin (bupropion) is not one of them) need to be started and up titration at much smaller dosages. I.e. Citalopram 50mg and in some people 2mg, then gradually medicine is tolerated better. Good luck and feel better. ...Read more

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Is it safe to take 75mg of wellbutrin, 10mg of celexa and 2mg of Abilify (aripiprazole) all at once?

Yes: It is safe to take those three medications together as long as the they were prescribed by the provider, and the provider who prescribed them is aware of the potential for interactions. As with any medications, if you experience side effects you should get in touch with the prescriber if they occur. ...Read more

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Why did my antidepressants (celexa and wellbutrin (bupropion) SR) stop suppressing my appetite after a few years on them?

Why did my antidepressants (celexa and wellbutrin (bupropion) SR) stop suppressing my appetite after a few years on them?

Your body can: accomodate to this medication side effect over time. Have you considered auricular acupuncture for healthy appetite suppression? ...Read more

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I'm currently on celexa 40 mg and Wellbutrin (bupropion) XL 150 mg. is it okay to take valerian as a supplement for anxiety?

I'm currently on celexa 40 mg and Wellbutrin (bupropion) XL  150 mg.  is it okay to take valerian as a supplement for anxiety?

Natural product: I assume you are doing well on Wellbutrin (bupropion) and Celexa, in appropriate therapeutic doses. Valerian is a natural product used for anxiety but most of all as a sleep aid. I don't believe there is any incompatibility if you do well with it. ...Read more

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Can wellbutrin (bupropion) cancel out the weight gain side effect of celexa?

To some degree: Wellbutrin, (bupropion) in most cases, either decreases appetite or has no effect on it. The most important way to avoid weight gain is a healthy balanced diet and exercise. Celexa may increase appetite but it is the number of calories consumed and not spent daily is what causes the weight gain. ...Read more

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Dr. Alan Ali
758 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more