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Doctor insights on: What To Expect The First Week On Prozac

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Dr. Heidi Fowler
1,047 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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I've been on prozac (fluoxetine) for 10 weeks now - 10mg for the first 7, and 20mg for the past 3. Helped anxiety at first, but not anymore. Stick it out longer?

I've been on prozac (fluoxetine) for 10 weeks now - 10mg for the first 7, and 20mg for the past 3. Helped anxiety at first, but not anymore. Stick it out longer?

Or go higher: Takes Prozac (fluoxetine) 4-6 was to start working (most SSRIs 2-3 was) dosage range 20-80 mg-- If you felt it helped initially I'd say stay with it.

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I just started Prozac (fluoxetine) (10mg) half dose for my first 2 weeks. I've noticed my right eye only is opening halfway is this related to Prozac (fluoxetine) in anyway?

UNLIKELY: I'VE BEEN PRESCRIBING PROZAC (fluoxetine) FOR 40 YEARS AND THIS IS A SIDE EFFECT I'VE NEVER RUN INTO. IT MAY POSSIBLY BE THE PROZAC (fluoxetine), BUT PROBABLY NOT. BE SURE BY STOPPING THE PROZAC (fluoxetine) (IT WILL BE OUT OF YOUR SYSTEM IN ABOUT A MONTH). OTHERWISE A NEUROLOGICAL CONSULT WOULD BE APPROPRIATE.

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I am switching from Zolft to Prozac (fluoxetine). I am on my first day at 75mg. Will take this 5 days then decrease by 25mg until none. When can I start Prozac (fluoxetine)20mg?

Check with doctor: It would be safe to start the prozac when you get to 25 mg of zoloft (sertraline). However, it is best that you check with the doctor prescribing these medicines as they know your complete history and other medications.

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Is there a way to go off cymbalta (duloxetine) by just switching completely over to Prozac the first day and continuing with prozac?

Is there a way to go off cymbalta (duloxetine) by just switching completely over to Prozac the first day and continuing with prozac?

To avoid: Ssri discontinuation symptoms while making the change - a cross titration could be useful. In other words, reducing the dose of one while increasing the dose of the other. And doing this progressively until you are off the first medication and you get to the target dose of the second medication.

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Tuesday was my last dose of 50mg of Paxil after eighteen years on, Thursday morning was my first dose of Prozac 60mg, would withdraw start today sat.?

Tuesday was my last dose of 50mg of Paxil after eighteen years on, Thursday morning was my first dose of Prozac 60mg, would withdraw start today sat.?

Can be immediate: In particular after being on the Paxil for so long, the serotonin discontinuation can be immediate and very intense. Even if another serotonin agent is substituted - like Prozac - it typically does not reduce symptoms. It might be best to very gradually taper the Paxil even after instituting the Prozac.

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Upped Prozac (fluoxetine) from 20mg to 40mg, in order to help getting of Valium. Experiencing more anxiety first 2 days, but this is normal right? Could it help?

Upped Prozac (fluoxetine) from 20mg to 40mg, in order to help getting of Valium. Experiencing more anxiety first 2 days, but this is normal right? Could it help?

Medication Effects: I commend you wanting to get off Valium if it had become habit forming. Of course you deserve relief from Anxiety. Valium is for Anxiety. Prozac (fluoxetine) is for depression, it can help with anxiety. Increasing Prozac (fluoxetine) from 20mg/day to 40mg/day is likely causing anxiety. See a Psychiatrist for diagnosis, need for medication, dose, benefits and side effects, Therapy, Breathing Relaxation, and Visual Imagery.

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I have been taking Prozac (fluoxetine) for my depression for the first couple of months I was even more unstable and very suicidal. What would have caused this?

I have been taking Prozac (fluoxetine) for my depression for the first couple of months I was even more unstable and very suicidal. What would have caused this?

Antidepressants: Not all antidepressants are for everyone. Your psychiatrist will help you select the right medication for you. We can not pinpoint what the exact cause was in your particular case. A black box warning exist for some antidepressants, mentioning situation like the one you describe. Discuss it with your dr.

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First few days on 20 mg of Prozac (fluoxetine) cause drowsiness (i.E., feeling sleepy during the day despite 8-9 hours of sleep). Could this subside eventually?

First few days on 20 mg of Prozac (fluoxetine) cause drowsiness (i.E., feeling sleepy during the day despite 8-9 hours of sleep). Could this subside eventually?

Side effects usually: Subside in 1-3 weeks. If you take the medication in the morning and feel sleepy during the day, try taking it at night and see if that reduces the daytime sleepiness. If it does not subside your prescriber may reduce the dose for a while and increase later when the side effect subsides. If it becomes intolerable and does not subside then an alternative medication may be necessary. Best regards.

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My 11 years child has moderate anxiety. His Pediatrician wrote Prozac (fluoxetine). We are hesitant to use. Should we consult Psychiatric first. How safe is Proza?

My 11 years child has moderate anxiety. His Pediatrician wrote Prozac (fluoxetine). We are hesitant to use. Should we consult Psychiatric first. How safe is Proza?

Ok: Prozac (fluoxetine) is a relatively safe anxiety medicine that has been largely used for quite some time. Compared with other medicines, this is less addictive, less dangerous and more tolerable side effects. A face to face conversation with your doctor on why Prozac (fluoxetine) would be the choice would be recommended. A second opinion with a psychiatrist could also be beneficial. Good luck.

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Can diarrhea affect the absorption of my Prozac (fluoxetine)? I have bad anxiety and depression like I did when I first started it.

Can diarrhea affect the absorption of my Prozac (fluoxetine)? I have bad anxiety and depression like I did when I first started it.

I doubt diarrhea: Would affect absorption of prozac (fluoxetine), (fluoxetine)unless its profuse diarrhea right after you take it. It may be that the prozac (fluoxetine) is no longer working for you. Talk to your Dr about this, especially if the diarrhea persists.

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Which SSRI is best to treat Anxiety/OCD in children. I heard Prozac (fluoxetine) can increase it at first. Is it best choice for anxoius but not depressed but kids?

Which SSRI is best to treat Anxiety/OCD in children. I heard Prozac (fluoxetine) can increase it at first. Is it best choice for anxoius but not depressed but kids?

No SSRI is "best": Medication choices for children are limited. Prozac (fluoxetine) is one that has been approved for Pediatric use and can be effective for both anxiety and depression. A Child Psychiatrist is best equipped to evaluate and decide on the medication needed. The risks of certain dangerous side effects are greater in children and young adults. I hope this helps.

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Which would you try first for binge eating if wellbutrin (bupropion) didn't work. Prozac or Zoloft? Which has better results and which is safer?

Which would you try first for binge eating if wellbutrin (bupropion) didn't work. Prozac or Zoloft? Which has better results and which is safer?

Several options.: Generally speaking Prozac (fluoxetine). However, I do not know the source of your problem. I would suggest you get with a mental health professional and figure this out. In addition, many people with this problem have been helped by Overeaters Annomous.

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I have insomnia and mild depression. I was just prescribed. 5 Klonopin and 10mg Elavil at bed time for sleep and 20 MG Prozac in the morning. My question is, since they are all 3 antidepr. Would you suggest I try Klonopin and Elavil first or all 3?

I have insomnia and mild depression. I was just prescribed. 5 Klonopin and 10mg Elavil at bed time for sleep and 20 MG Prozac in the morning. My question is, since they are all 3 antidepr. Would you suggest I try Klonopin and Elavil first or all 3?

It depends upon: Upon several factors, and without knowing more about you it’s hard to say. You may wish to speak to your prescriber and ask these specific questions. Prozac and Elavil are different types of antidepressants, and Klonopin (clonazepam) is a benzodiazepine; none of them are specifically for insomnia, but may cause sedation which may be why you were instructed to take them at night. Good luck!

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How will I know Prozac (fluoxetine) is working? I have taken it two weeks.

How will I know Prozac (fluoxetine) is working? I have taken it two weeks.

2 to 6 Weeks: Your medication is working when your treatment goals for are being met. For example, if your your goals include being motivated to get out of bed each morning and performing certain tasks: then you would find it easier to get up each day and easier to complete the tasks. Most patients begin to feel better after two weeks. But for some it may take up to six weeks. Be patient and talk to your md.

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Been taking 20mg of Prozac for 5 years last few weeks been taking every other day is that fine?

Why are you changing: How you are taking the dosage? Is it no longer working or experiencing side-effects? I may noy hurt but I would not change my dosage schedule unless it's ok 'd by the doctor. Since you been on it a while you don't want to disrupt your baseline.

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How long would it take for 5mg of Prozac (fluoxetine) to leave my system if I've been taking it for 5 weeks?

How long would it take for 5mg of Prozac (fluoxetine) to leave my system if I've been taking it for 5 weeks?

Prozac (fluoxetine): Is sometimes used on a temporary basis to minimize the affects of coming off other SSRI agents (yes there are SSRI withdrawal symptoms) Prozac (fluoxetine) is typically given in the 10-20 mg dose for this purpose for a 7-14 days. At 5 mg discontinuation after 5 weeks would require about 5-8 days. (depending on renal function)

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Could it be healthy to be on Prozac (fluoxetine) for at least 3 weeks and have the same problems as well as new problems?

Could it be healthy to be on Prozac (fluoxetine) for at least 3 weeks and have the same problems as well as new problems?

Possibly: It often takes 4 to 6 weeks to get high enough serotonin levels for Prozac (fluoxetine) to be effective. However, it is likely that side effects could be apparent much earlier.

Dr. Alan Ali
768 Doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more