Doctor insights on:
What To Do To Normalize Sgpt And Sgot
Why are they up?: Elevated liver enzymes (sgpt, sgot, also called ast and alt) are signs of inflammation in the liver, but they do not tell you the cause. The treatment will depend on the cause. A few of the common causes are overuse of alcohol. Being overweight, certain medications, infections, autoimmune diseases, and metabolic diseases (copper or iron storage diseases). Further investigation is needed.See 1 more doctor answer
After taking saaz 500 (salfasalazine) for a month test report shows alt (sgpt) is 188 iu/l and ast (sgot) is 90 iu/l. How to normalize the levels?
It depends: Sulfasalazine may be the cause of abnormal liver tests, but only in a very small percentage of patients. If you also have a fever and rash, it could be a type of hypersensitivity (allergic reaction) and might need to be stopped. You also could have some other liver problems that might need to be treated (like chronic hepatitis infection or other drugs that affect your liver). See your doctor!
Depends: Your SGOT is minimally elevated. It may due to alcohol intake, some medications you are taking, or from being overweight, or due to an infection. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that.
FInd the cause: Elevated liver transaminases usually call for a repeat off alcohol and meds. If still up, a check for the hepatitis family, hemochromatosis, wilson's, autoimmune hepatitis. As often as not, what the liver is really asking for is for you to get back to a fitness-focused lifestyle. Best wishes.
Drinking: Drinking alcohol raises these markers a whole lot more than smoking. Being overweight can also result in elevated levels. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex.
Elevated liver funct: I can't say there is a cure for elevated liver functions, but we can treat the condition. First of all we need to find out the cause. You need to see your physician for a comprehensive history and physical exam, history of exposure to toxin, infections, drug history, diet history. You may need to have a liver US and maybe a fallow up liver CT.
Depends: Is you SGPT and SGOT elevated? If yes, then the first order of business is to determine why. If you drink alcohol, stop entirely. If you are overweight, reduce weight and exercise would help in that. Do you have viral infection of the liver - that would need additional tests. It would be prudent to consult your doctor.
Workup: If available, get a proper genetic workup even if no one else in the family is affected. If your amylase is high but lipase normal and there is nothing on imaging pointing to the pancreas, this may be macroamylasemia. If the pancreatitis is real, checking the cystic fibrosis and trypsinogen loci is indicated. This may be one piece in the puzzle. Be persistent.
Yes: You should see a hepatologist and have it futher looked in to.
Liver: You have some type of liver problem. This can be of the liver itself or obstruction outside of liver need checked
Usually not: The gall stone when present in the gall bladder does not affect the liver enzymes. Only if it is obstructing the common bile duct, it can cause abnormal liver function but the patient is very sick in that condition. Another cause for liver function abnormality should be investigated.
Fatty liver: You already have a reason. You have abnormal fat causing damage to your liver. We cannot guess if you have other conditions. But you need a frank discussion with your physician on how to get better.
Depends: If he's been sober for a few days (good!), they're likely to be normal. If he's abusing alcohol enough to hurt himself / others, they can still be within the normal range, or they can be high. If they're above 400, he's probably got alcoholic hepatitis. Sgpt tends to be lower than SGOT in drinkers. The diagnosis of alcoholism is clinical, not lab based -- but you knew that.
Get worked up: The Febuxostat that you are taking for your elevated uric acid is famous for raising SGOT and sgpt. Your physician needs to take you off this medication and off alcohol for a two week trial. If he/she does not do this at your next appointment, request a consult. If the sgot/sgpt are still up, you'll need to be worked up for hepatitis b and c, wilson's, hemochromatosis, and nafld.
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