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Doctor insights on: What To Do After Positive Ana Test

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If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do?  (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus.All this needs to be correlated by your doc/specialist ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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Is their any other tests to get diagnosis for my case after positive ANA test, leukocytosis, sever joint pain and itchy skin patches ?

Is their any other tests to get diagnosis for my case after positive ANA test, leukocytosis, sever joint pain and itchy skin patches ?

Positive ana: There are many other tests that can help confirm a diagnosis. Additional blood tests to determine the exact antibody that is causing the positive ANA should be done. A skin biopsy may be indicated. It is possible that your doctor has already arrived at a diagnosis from your constellation of symptoms. ...Read more

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What does a positive ANA test mean?

What does a positive ANA test mean?

Antibodies vs nuclei: The titer (how much antibody power is present) is important -- 1:40 seldom means much, 1:320 would worry most folks -- as does the pattern, but like all lab tests, its meaning comes from the setting. Typically a screen for lupus and related diseases, many older folks who are healthy run a low titer. ...Read more

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What does a positive ANA test mean?

What does a positive ANA test mean?

Antibodies vs nuclei: The titer (how much antibody power is present) is important -- 1:40 seldom means much, 1:320 would worry most folks -- as does the pattern, but like all lab tests, its meaning comes from the setting. Typically a screen for lupus and related diseases, many older folks who are healthy run a low titer. ...Read more

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What do you suggest if positive ANA test, what does this mean?

What do you suggest if positive ANA test, what does this mean?

Many reasons: Although the + ANA is a screening test for lupus erythematosus. But most people with a + ANA do not have lupus. We see it in a lot of conditions including, thyroid disease,allergic conditions, liver disease, other connective tissue etc. Your physicians can have you see a rheumatologist to clarify why you have a + ANA and whether you have lupus or another connective tissue disea ...Read more

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2 positive ANA titres 1:160 speckled. All manual diff tests neg. Is this something to worry about?

2 positive ANA titres 1:160 speckled. All manual diff tests neg. Is this something to worry about?

Possibly: The ANA is not very specific. It can be possible in numerous diseases including viral diseases. It can also be positive in individuals without any disease. The ANA needs to be interpreted in the clinical setting to be properly evaluated. ...Read more

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I have a positive ANA test but it reads as 6? I'm used to seeing them as 1:40, 1:80 etc... What does 6 mean?

Possibly nothing: This is certainly non-standard reporting. It suggests that on cannot have confidence in the reporting laboratory and the test should be repeated elsewhere. ...Read more

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I recently got a positive ANA test 1:80 homogenous with no other symptoms. What does this mean? 32 yrs old healthy.

Positive ana: 1:80- not that high. Worry if > 1:160.Ana tests for autoimmune disease. In recent study ~13% of well blood donors had + ana with no symptoms, of those, 72% did not develop any issues with ~ 4 years of follow up. Sometimes other conditions like thyroiditis, mono, chronic disease,multiple sclerosis can cause positive ana as can meds :INH,hydralazine,procainamide remicade (infliximab). FU with rheumatologist. ...Read more

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Can syphilis cause a positive ANA test?

No: However lupus can cause the screening test for syphilis (the rpr) to be falsely positive. ...Read more