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Doctor insights on: What To Do After Positive Ana Test

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If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus. All this needs to be correlated by your doc/specialist ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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Is their any other tests to get diagnosis for my case after positive ANA test, leukocytosis, sever joint pain and itchy skin patches?

Is their any other tests to get diagnosis for my case after positive ANA test, leukocytosis, sever joint pain and itchy skin patches?

Positive ana: There are many other tests that can help confirm a diagnosis. Additional blood tests to determine the exact antibody that is causing the positive ANA should be done. A skin biopsy may be indicated. It is possible that your doctor has already arrived at a diagnosis from your constellation of symptoms. ...Read more

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What does a positive ANA test mean?

What does a positive ANA test mean?

Antibodies vs nuclei: The titer (how much antibody power is present) is important -- 1:40 seldom means much, 1:320 would worry most folks -- as does the pattern, but like all lab tests, its meaning comes from the setting. Typically a screen for lupus and related diseases, many older folks who are healthy run a low titer. ...Read more

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What does a positive ANA test mean?

What does a positive ANA test mean?

Antibodies vs nuclei: The titer (how much antibody power is present) is important -- 1:40 seldom means much, 1:320 would worry most folks -- as does the pattern, but like all lab tests, its meaning comes from the setting. Typically a screen for lupus and related diseases, many older folks who are healthy run a low titer. ...Read more

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What do you suggest if positive ANA test, what does this mean?

What do you suggest if positive ANA test, what does this mean?

Many reasons: Although the + ANA is a screening test for lupus erythematosus. But most people with a + ANA do not have lupus. We see it in a lot of conditions including, thyroid disease, allergic conditions, liver disease, other connective tissue etc. Your physicians can have you see a rheumatologist to clarify why you have a + ANA and whether you have lupus or another connective tissue disea ...Read more

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2 positive ANA titres 1:160 speckled. All manual diff tests neg. Is this something to worry about?

2 positive ANA titres 1:160 speckled. All manual diff tests neg. Is this something to worry about?

Possibly: The ANA is not very specific. It can be possible in numerous diseases including viral diseases. It can also be positive in individuals without any disease. The ANA needs to be interpreted in the clinical setting to be properly evaluated. ...Read more

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I have a positive ANA test but it reads as 6? I'm used to seeing them as 1:40, 1:80 etc... What does 6 mean?

Possibly nothing: This is certainly non-standard reporting. It suggests that on cannot have confidence in the reporting laboratory and the test should be repeated elsewhere. ...Read more

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I recently got a positive ANA test 1:80 homogenous with no other symptoms. What does this mean? 32 yrs old healthy.

Positive ana: 1:80- not that high. Worry if > 1:160.Ana tests for autoimmune disease. In recent study ~13% of well blood donors had + ana with no symptoms, of those, 72% did not develop any issues with ~ 4 years of follow up. Sometimes other conditions like thyroiditis, mono, chronic disease, multiple sclerosis can cause positive ana as can meds :INH, hydralazine, procainamide remicade (infliximab). FU with rheumatologist. ...Read more

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Can syphilis cause a positive ANA test?

No: However lupus can cause the screening test for syphilis (the rpr) to be falsely positive. ...Read more

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What does t means a positive ANA test and ifa?

What does t means a positive ANA test and ifa?

Only a test and: Only a test and that result suggests that it is not the standard assay. If there are general body symptoms, then a rheumatologist would be helpful. ...Read more

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What about leukocytosis and positive ANA test?

Autoimmunity?: Positive ANA indicates that there are presence antibodies against components of nucleus of your own cells. Our body is not supposed to make antibodies against our cells. Something happens, which leads antibodies being produced against cells of different organs such as thyroid glands and pancreas. Leukocytosis is the state of increased white cell count indicating some inflammation. ...Read more

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What are the causes of a positive ANA test result?

Many: ANA can be positive in many diseases and in many apparently healthy people. By itself, it does not mean much other than pointing to a higher but not certain risk for an individual to develop an autoimmune disease. ...Read more

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What do you suggest if positive ANA test, type 1 diabetic - help?

What do you suggest if positive ANA test, type 1 diabetic - help?

Nothing, unless...: Unless you have symptoms of another autoimmune disease such as swollen joints, unexplained rashes, fevers, etc, the ANA test is not particularly helpful for making any diagnosis since 25-30% of healthy people have a positive ANA test. Labs such as ESR, DS-DNA, C3, C4 are more helpful if abnormal along with symptoms of lupus. See your doc and ask for a referral to a rheumatologist if you are concerned ...Read more

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Can prolonged elevated levels of prolactin lead to a positive ANA test?

No: Prolactin is a hormone produced by your pituitary gland that is involved in milk production. Certain drugs, pituitary tumors, breast stimulation and food may increase the levels. ANA is an antibody test associated with a disease called lupus. ...Read more

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What happens with a positive ANA test even thought I don't have a titer result yet?

What happens with a positive ANA test even thought I don't have a titer result yet?

See details: A positive screen means nothing. You need a titer to know if the test is truly positive. A positive can be seen in numerous diseases and even in normals. The result needs to be correlated with the clinical picture. ...Read more

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What does it mean to have a positive ANA blood test?

What does it mean to have a positive ANA blood test?

Nada without disease: If you do not have a clinical disease or symptoms then it simply means you have a positive test (maybe 1/3 of the population has a "positive" test). If the titer is very high (greater than 1:640) you should probably be followed to see if a disease is developing. ...Read more

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Ana test results question - how many people have ANA positive but don't ever get lupus?

Age and gender: Positive ANA test is commoner in older people and women. Up to 25% of the people may have positive ANA test at some time or the other. Only 0.1-0.15% of the population has systemic lupus. ...Read more

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Would a negative ANA rule out lymphoma? Does lymphoma cause a positive ANA test result?

It does not: At your age, if you have lymphoma it's probably Hodgkin's. ANA really has nothing to do with malignant lymphoma. If you're worried about big lymph nodest, trust me -- lymphoma nodes are obviously very abnormal. Best wishes, and I hope you'll always stay actively involved with your health. ...Read more

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Tomorrow, I have to do another ANA test, will me taking plaquinil cause a false positive ana?

No: Wondering why you are taking a medication often prescribed for lupus if you don't list either lupus or another reason for the medicine. Anti-nuclear antibody tests aren't reported as "positive" or "negative" but as a titer. They remain an important screening test for lupus. ...Read more

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I have a 1:320 positive ANA test with nucleolar pattern. Are there other explanations for this aside from SS? I don't really have the symptoms of it

Elevated ANA nucleo: Why was the test done? What symptoms? 1;320 is usually considered elevated. Did they do Scl or anti-centromere or Topo I or antiRNA polymerase III, anti- U2 RNP, anti- Th these are also markers of scleroderma./CREST. Liver/GI disease Crohns, , other autoimmune diseases like thyroid, meds liek Dilantin, procaine, hydralazine can elevate ANA. Rrepeat in 2-4 week f/u/ w/ rheumatolog ...Read more

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My blood test was positive ANA and high rnp what does that mean?

My blood test was positive ANA and high rnp what does that mean?

See below: These test results have to be interpreted in context of your symptoms and these are frequently false positives. Seeing a rheumatologist can help you better determine this. If they are a true positive, this can be seen with an autoimmune disease known as mixed connective tissue disease. ...Read more

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What does a high positive ANA ifa test and negative choice antibody test mean?

See details: I have never heard of a choice antibody test. I positive ANA must be evaluated in the context of the clinical picture. It is a screening test for lupus but can be positive in numerous other diseases and often in people without any disease. ...Read more

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What does dual pattern on a positive ANA blood test mean? Other blood work is fine?

What does dual pattern on a positive ANA blood test mean? Other blood work is fine?

Depends on symptoms: ANA is a screen for lupus. The pattern was used in the past to assist in diagnosing lupus and related conditions, but we have better tests (i.e. Ena panel) that has made patterns less useful. But you cannot over interpret this test: ANA positivity, regardless of pattern, is not helpful without knowing your symptoms. Everything boils down to symptoms;; rheum md would be very helpful. ...Read more

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Does a positive ANA of 1;640 spec pattern suggest cancer if all other test are negative?

ANA: An ANA is not a diagnostic test for cancer. It has no reliabilty for screening cancer. It is estimated that about 30% of all patients will have false positive. Unless you have symptoms consistent with an autoimmune process, it is not a diagnostic test. ...Read more

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Ana positive result (1:1280) in blood tests. All other blood tests normal. What could that mean?

Ana positive result (1:1280) in blood tests. All other blood tests normal. What could that mean?

Risk: That may mean you are at higher risk to develop an autoimmune disorders in the future. Since you are suffering from back pain already at your young age, perhaps you should see a rheumatologist to find out if there is any autoimmune disorder affecting your back unless the cause for the back pain is already known. ...Read more

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I have had multiple positive ANA and they do the next step tests to check for lupus and it comes back negative. Why do they keep checking my ana?

I don't know: Imo, there is no need to constantly repeat an ana. It is a waste of time and money. Positive is positive and constantly repeating it will not change that. ...Read more

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Tested positive just couple weeks ago for hashimotos now positive ana also, been feeling horrible does it mean I have lupus? Any further tests? Help

Yes: More tests and clinical evaluation to confirm or rule out SLE. ANA can be positive in Hashimoto's, symptoms of fatigue and being tired are common to many autoimmune disorders. Talk to your doctor /see a rheumatologist for evaluation, wish you wellness ...Read more

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Can cervical cancer show in a positive ANA test?

Can cervical cancer show in a positive ANA test?

No. An ANA: Ani-nuclear antibody is a lupus test, and can be positive in other rheumatological diseases/ cervix cancer needs to be diagnosed by an internal pelvic exam and a biopsy. ...Read more

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I had a positive ANA test and positive smith antibodies. Will they find ra?

I had a positive ANA test and positive smith antibodies. Will they find ra?

Lupus: A high-titer ANA and a positive anti-sm (smith) usually means systemic lupus rather than rheumatoid arthritis. This is much more manageable today than in the past. No lab means much in isolation, and your physician ordered these labs because he/she suspected lupus. If the diagnosis is established, you'll probably want to join a community group for people with sle. Good luck. ...Read more

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What would cause platelet count in sept 797 and new count in march of 324? Ana positive test

What would cause platelet count in sept 797 and new count in march of 324? Ana positive test

Platelets: Platelets tend to be an acute phase reactant that can become very elevated during an acute infection or an acute flare of the lupus. When the inflammatory process is under better control, the platelets will return to a normal level. This is very common. ...Read more

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I have had many symptoms of sle over the past 8 yrs, and now have a positive ANA test. Are there any add'l test before I get a diagnosis?

Rheumatologist: There are defined criteria for the diagnosis of sle and positive ANA is just one of the factors. You should consult a rheumatologist for a proper diagnostic work-up. ...Read more

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I have a positive Ana test at 1:16 homogenous. Lots of symptoms with numbness/fatigue. I don't understand what the result means can someone help?

Autoimmunity: A rheumatologist can help evaluate you for other conditions that fall into autoimmune diseases or connective tissue disorders. There are so many possibilities and it sounds like your having a direct effect from your condition. It may stay mild or become part of something much more severe. ...Read more