Doctor insights on:
What Symptoms Of Pernicious Anemia Are The Most Common
They can be subtle.: Pernicious anemia is caused by vitamin B12 deficiency. The name refers to the fact that symptoms can come on so slowly that you might not be aware of them. If present, pa can cause fatigue due to anemia, mental changes that can include memory deficits or dementia, or nerve damage that causes numbness in the feet and possible gait disturbances. You can get all of them, or none and have pa. ...Read more
Most likely.....: Folic acid, or possibly B12 in the setting of deficient but not completely absent intrinsic factor synthesis. The eqivalent of pernicious anemia can be caused by inadequate B12 intake, inadequate intrinsic factor production by parietal cells (autoimmune destruction, atrophic gastritis, etc.) or inadequate absorption at the terminal ileum (also for many reasons). Some other rare reasons as well. ...Read more
I have symptoms of severe B12 deficiency/pernicious anemia but also derealization, brain damage, and heart problems could these occur from the B12 def.?
Yes except heart: B12 deficiency can cause a variety of neurological symptoms including "derealization"; it can adversely affect brain function but that damage should be reversible. It can cause high homocysteine which increases risk of cardiovascular disease ; anemia puts stress on hearts, but it should not directly cause heart problems I someone your age. See http://bit. Ly/1hlbiaz. ...Read more
B12 deficiency: It is an autoimmune disease in which your body develops antibodies against intrinsic factor and gastric parietal cells which are needed to absorb b12, a vital nutrient. These patients will need to get im injections of b 12 lifeterm since they cannot absorb B12 naturally from their diet. ...Read more
Not usually.: Classical pernicious anemia is caused by auto-antibodies against intrinsic factor-producing parietal cells of the stomach. Treatment is lifelong vitamin B12 administration, which is safer than using immunosuppressive medications that could lead to severe infections. Other kinds of B12 deficiency can possibly cured depending on the cause. ...Read more
Cobalamin therapy: Try a trial of vitamin B12 (cobalamin) first and have a physician to repeat lab to ensure adequate dose. Also it may need additional therapies for cobalamin deficiency due to underlying diseases involving intestine or pancreas. Please check for Folic Acid deficiency as well and this may be related to nutritional deficiency. If you are a vegetarian, please take vitamin B12 daily. ...Read moreSee 1 more doctor answer
Probably no: If you have pernicious anemia you do not absorb B12 effectively. That is easily fixed with either B12 injections or large B12 oral doses daily. Unfortunately, patients with B12 deficiency often have other associated autoimmune issues that develop. In general though, pa alone will not shorten life as long as you treat it correctly. ...Read more
Autoimmune disease: Pernicious anemia is an autoimmune disease producing autoantibodies against intrinsic factor found in the lining of the stomach. This leads to lack of absorption of vitamin B12 which is important in making blood cells and for nourishment of the nervous system. Treatment would be by replacement of B12 via injections or absorption into the body by other means (nasal spray). ...Read more
Depends on ur dfn: Pernicious anemia can be used to describe a heriditary condition where you lack the cofacter needed to absorb b12. This may not emerge as a problem until older. If you develop a condition where you loose the absorbtive surfaces of the small intestine thru surgery or disease, you can acquire the problem. A lack of B12 in the diet may cause anemia some will label pa. ...Read moreSee 1 more doctor answer
Due 2 B12 deficiency: It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily treatable with replacement therapy. ...Read moreSee 2 more doctor answers
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