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Doctor insights on: What Should I Do If I Take Too Much Herceptin By Mistake

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What should I do if I take too much herceptin (trastuzumab) by mistake?

What should I do if I take too much herceptin (trastuzumab) by mistake?

Overdose is rare: Herceptin (trastuzumab) is what is referred to as a monoclonal antibody that is used to treat some types of cancer(breast, stomach). It is typically administered by IV in a controlled setting so overdose is rare. Although cardiac issues may arise in 2-7% of patients who recieve this, it does not appear to be dose related. An "accidental overdose" has not been shown to be detrimental. ...Read more

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Dr. Lonnie Smith
59 doctors shared insights

Trastuzumab (Definition)

Trastuzumab is an antibody based agent which is a kind of ...Read more


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Im a her2 stage 3 breast cancer parient . I have already finished my herceptin (trastuzumab) what would be the next medication would I take as maintenance medicine?

Im a her2 stage 3 breast cancer parient . I have already finished my herceptin (trastuzumab) what would be the next medication would I take as maintenance  medicine?

It depends on your b: There are many medicines used to treat breast cancer. Besides herceptin, (trastuzumab) your doctor may prescribe chemotherapy or hormonal therpy depending on the subtype of breast cancer that you have. Hormonal therpies are used for er+ cancers....So check if your tumor wass er+ or er-. Ask you oncologist to address this question. ...Read more

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Im a her2 breast cancer patient stage 3 . Due to financial constraint I finished 12 sessions of herceptin instead of 17 , is there any medicine I could take as a replacement of the herceptin ? I'm from the philippines and herceptin is very expensive.

Im a  her2 breast cancer patient stage 3 . Due to financial constraint I  finished 12 sessions of herceptin instead of 17 , is there any medicine I could take as a replacement of the herceptin ? I'm from the philippines and herceptin is very expensive.

Unlikely: There is not a less expensive substitute. The manufacturer might have some support programs, but I am not sure if it is available in your case. You still have gotten benefit from your treatment. Check with your oncologist to see if a support through genentech is available. ...Read more

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What are trastuzumab and herceptin?

What are trastuzumab and herceptin?

Biologic Therapy: Herceptin/trastuzumab is an antibody to a cell surface proteint coded for by the her2neu gene. Its present in some normal cells but in a subset of breast cancers (10-15%) there are multiple copies of the gene producing large amounts of the protein. The herceptin/trastuzumab antibody binds to that protein and reduces that aggressive nature of her2+cancer. It is usually given with chemo. ...Read more

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How does herceptin (trastuzumab) work?

How does herceptin (trastuzumab) work?

Binds to tumor: Herceptin (trastuzumab) is a man-made antibody that binds to cancer cells if they express the her2 receptor. It acts like "seasoning" for the immune system, attracting immune cells which kill the tumor cells. That's a simplistic explanation, because no one really understands what happens when Herceptin (trastuzumab) binds to tumor cells. There are many theories, but we know immune cells are necessary for it to work. ...Read more

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Where can I buy herceptin(trastuzumab)?

Where can I buy herceptin(trastuzumab)?

Herceptin (trastuzumab) is : A medication that is typically given by an oncologist. Consult your doctor. ...Read more

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Where can you get herceptin (trastuzumab)?

Herceptin (trastuzumab): Herceptin (trastuzumab) is a prescription medication that prescribed by a medical oncologist for breast cancers that are HER2/neu positive or HER2/neu amplified. It is administered intravenously and is not available over the counter. ...Read more

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What is the cost of herceptin (trastuzumab)?

What is the cost of herceptin (trastuzumab)?

Thousands!: In the us, the cost of Herceptin (trastuzumab) depends on who gives it to you and what kind of insurance you have. Patient's bills are in the range of $2000 to over &7000 per treatment. Why the difference? Medicare limits how much the cost can be "marked up" from the purchase price, but other insurance companies aren't as strict. So... The cost is what the market will bear, sadly. ...Read more

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How exactly does herceptin (trastuzumab) work?

Blocks cell growth: Herceptin (trastuzumab) is a "monoclonal antibody". It is a protein that binds to receptors on breast cancer cells called her-2. Her-2 causes breast cancer cells to grow uncontrollably. When Herceptin (trastuzumab) binds to these cells, it slows their growth. However, not all breast cancer cells contain the her-2 receptors. Patients must be tested for the presence of her-2 receptors before they are started on herceptin (trastuzumab). ...Read more

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What are the effects of herceptin (trastuzumab)?

What are the effects of herceptin (trastuzumab)?

Killing cancer cells: Herceptin (trastuzumab) is an antibody, which is the y-shaped green thing in the picture. It sticks to the her2 protein which is present on some breast cancers (and other cancers). Herceptin (trastuzumab) seems to help the body's immune cells "see" and attack the cancer cells. For women with her2 positive breast cancer, it decreases the risk of the cancer returning by almost 50%! ...Read more

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Who should avoid taking herceptin (trastuzumab)?

Who should avoid taking herceptin (trastuzumab)?

History heart failur: There are many considerations, but you should not take Herceptin (trastuzumab) if you have a history of congestive heart failure. Visit with your doctor to see if Herceptin (trastuzumab) is right for you. ...Read more

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How long could herceptin (trastuzumab) stay in the body ?

About a week: Half life of 2 days. That means that half the blood level is gone in two days. Then, another 50% is gone in another two days, etc. ...Read more

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Which company offers the best quality of herceptin (trastuzumab)?

Genentech: The US patent on trastuzumab ("Herceptin") expires in June of 2019, so only Genentech is allowed to produce it. In Europe, the patent expired in June of 2014, but I don't know if the European Medicines Agency has yet approved any biosimilars ("generics"). ...Read more

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Can anyone recommend websites to research herceptin (trastuzumab)?

Yes: Try www.Cancer.Gov. This is the national institute of health website, so it is free from commercial (pharmaceutical company) bias. ...Read more

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Is it common to gain weight after finishing herceptin (trastuzumab)?

Not herceptin (trastuzumab): Weight gain is not directly associated to herceptin (trastuzumab). Herceptin (trastuzumab) is commonly used in combination with cytotoxic chemotherapy. Weight gain likely is associated with decrease of activity related to cancer and its treatment - and could be associated to the use of steroid which is given prior to chemo. It can contribute to water retention and some changes in fat distribution in the body--> weight gain. ...Read more

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Can you tell me what are contraindications of herceptin (trastuzumab)?

None except...: There are no contraindications to this medication but it should not be used in pregnant women because of possible harm to the baby. ...Read more

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Do you know which drug company offer the best quality of herceptin (trastuzumab)?

Genentech: I'm not sure what you mean. Genentech created Herceptin® (trastuzumab) -- http://www.gene.com/patients/medicines/herceptin. I haven't encountered generic trastuzumab in the U.S. I'm not up to date on anything ex-US except -- Roche wins battle against India sales of generic cancer drug -- http://www.ft.com/cms/s/0/f1d8b1ce-8fd6-11e3-aee9-00144feab7de.html#axzz4038uSIed ...Read more

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Any suggestions on which company offer the best quality of herceptin (trastuzumab)?

Who knows : There are some studies looking at trastuzumab generic vs brand, but ongoing. Unfortunately it won't be easy to figure out which generics are the closest to that manufactured by the company that did the original studies, Genentech. ...Read more

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Is herceptin (trastuzumab) still effective if I stop for 2 mos then continue it because of unavoidable circumstances?

Is herceptin (trastuzumab) still effective if I stop for 2 mos then continue it because of unavoidable circumstances?

Yes!: In the us, the studies of Herceptin (trastuzumab) looked at a full year of treatment for patients with curable breast cancer. Herceptin (trastuzumab) is given every three weeks for 17 doses. But why a year? It was chosen at random. In finland, a similar study gave only 9 weeks of herceptin (trastuzumab)... And patients did just as well! so i think you should feel reassured that you will still have a positive effect from the drug! ...Read more

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Its been 4 mos now after my 12 session of herceptin (trastuzumab) , and I decided to continue my herceptin (trastuzumab), inorder to copmlete the cycle . Iis still helpful or effective after the 4 mos break?

Yea: After the hera trial was published and the data on trastuzumab was made available, everyone did not get trastuzumab. Once the data was published, the consensus was if it was less than a year, and the patient was her2 positive, one could still receive it. So yes, continue it. Probably the most effective drug for her2 positive disease. Hope this helps. ...Read more

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What causes herceptin (trastuzumab) headache?

What causes herceptin (trastuzumab) headache?

Let me explain: The thoery is Herceptin (trastuzumab) infusion cause contious vasodilatation which is thought to provoke the headache. ...Read more

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Are there any pine derivatives in herceptin (trastuzumab)?

Not that I am aware.: Herceptin (trastuzumab) is a bio-engineered monoclonal antibody treatment for her2 positive breast cancer patients. There are no known pine derivatives in this medicine of which I am aware. Hope that this is helpful. ...Read more

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Dr. Al Hegab
65 doctors shared insights

Herceptin (Definition)

Herceptin ...Read more