Top
10
Doctor insights on: What Is Wegener Granulomatosis

Share
1

1
What is wegener's granulomatosis?

What is wegener's granulomatosis?

Wegener's: Granulomatosis is an incurable form of vasculitis (inflammation of blood vessels) that affects the nose, lungs, kidneys, and other organs. ...Read more

Dr. Jan Lei Iwata
30 doctors shared insights

Granulomatosis (Definition)

A process associated with a tissue reacton involving monocytes and tissue macrophages. Clasically this was seen in infections, like tuberculosis and some fungal processes. It is also seen and inflammatory and reactive ...Read more


2

2
Please advise what is wegener's granulomatosis?

Please advise what is wegener's granulomatosis?

Immune vasculitis: The antobodies found in the test and that cause the disease are directed against an antigen within neutrohils. Untreated, Wegener's (granulomatous angiitis for those who cannot forgive Dr. Wegener's being a German during WWII) is fatal. Nowadays it can be managed using cyclophosphamide and/or perhaps other powerful agents and most people eventually recover. ...Read more

3

3
Could a bronchoscopy tell what caused wegener's granulomatosis?

Could a bronchoscopy tell what caused wegener's granulomatosis?

No it cannot: A bronchoscopy is useful for identifying that wegener's is affecting the lungs but it will not tell you the cause. Wegener's is in a class of conditions known as autoimmune. This is where the body does not recognize its own cells as being "self". In turn an immune response causes inflammation in the lungs, eyes and sinuses (the classic locatioins in the body to be affected by wegeners). ...Read more

See 2 more doctor answers
4

4
What is wegener's granulomatosis vasculitis?

What is wegener's granulomatosis vasculitis?

See details: It is a form of vasculitis effecting medium sized arteries and associated with a positive canca blood test. It usually begins as chronic sinusitis but with time can effect many other organ systems including eyes, heart, kidneys, joints, lungs and the nervous system. There are very effective treatments available. ...Read more

6

6
What are symptoms of wegener's granulomatosis?

See details: The most common presenting symptom is a chronic sinusitis but there can be numerous other issues associated with wegener's including arthritis, pneumonia, eye problems, kidney disease and cardiac and neurologic issues. ...Read more

7

7
What are the tests for wegener's granulomatosis?

What are the tests for wegener's granulomatosis?

ANCA and biopsy: The most useful blood test is an anca with titer and pattern, and pr3/mpo confirmation. Biopsy of the affected tissue is also important. Imaging studies of the lungs and sinuses can be useful as well as blood and urine tests looking for kidney damage. Finally, EMG might be needed if there is concern for nerve damage. ...Read more

See 1 more doctor answer
8

8
What's a good description of wegener's granulomatosis vasculitis?

Systemic vasculitis: Wegener's is a systemic vasculitis associated with the presence of specific blood tests known as a canca or pr3 antibodies. It usually presents as chronic sinusitis and more rarely pneumonia but can effect other areas of the body especially the kidneys, eyes, heart and nervous system. It is very serious but newer medications have provided effective treatment in most cases. ...Read more

See 1 more doctor answer
9

9
Causes of wegeners granulomatosis and treatment?

Autoimmune disease: Like all autoimmune diseases, the cause is not really known, but likely a combination of genetic factors and environmental exposures (e.g., infections, chemicals, pollutants). Treatment depends on how severe disease it is. Typically steroids (e.g. Prednisone) and if severe, Cytoxan or rituxan (rituximab). If limited disease (just nasal/upper airway involvement), Methotrexate may be sufficient. ...Read more

10

10
What is the disease wegeners granulamatosis in kids?

What is the disease wegeners granulamatosis in kids?

WG: Wegener’s granulomatosis (WG) is a rare disease that causes the walls of blood vessels to become inflamed (called vasculitis). This limits blood flow to tissues and can affect any organ. WG is a type of autoimmune disease. This means the body’s immune system attacks its own tissues. Its cause is unknown. ...Read more

Dr. Gregory Moneta
32 doctors shared insights

Wegener's Granulomatosis (Definition)

Wegener's Granulomatosis is a medical condition in which the blood vessels supplying the nose, lungs, kidneys and other organs become inflamed. Symptoms include nose bleeds, difficulty ...Read more