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Doctor insights on: What Is Trisomy

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What is trisomy?

What is trisomy?

Error in formation: Humans have 23 pairs of chromosomes or 46 total. During the formation of the egg, each pair splits and one of each travels to the egg. At conception, the sperm brings one of each & the new embryo now has 23 pairs (two of each). Any time one of the chromosome pairs doesn't split & gives a pair to the egg, a third will come from the sperm and a trisomy of that chromosome is formed. ...Read more

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Trisomy (Definition)

Ordinary chromosomal traits require a pair of chromosomes to determine the traits. Occasionally, as a mistake in cellular division, there is a tripling of one of the chromosomes. When these occur, they usually cause unpleasant, and sometimes deadly conditions in the inheritor of these traits (e.g. Down's). Many we do not know about as they are ...Read more


Dr. Liza Kunz Dr. Kunz
2 doctors agreed:
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What is trisomy 23? Whats the official name for it?

Dr. Liza Kunz Dr. Kunz
2 doctors agreed:
What is trisomy 23? Whats the official name for it?

Klinefelter's: This link has some great information about klinefelters: http://trisomydisorders.Wordpress.Com/2008/10/30/trisomy-23/. ...Read more

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What other trisomy's are there besides 21 and what do they cause?

What other trisomy's are there besides 21 and what do they cause?

Many: Only about 1 in four conceptions go to term. The others are mostly all affected by either trisomies or monosomies, and are incompatible with survival. Most die before implantation, and a mom won't even know that conception had occurred. May may implant, but die either before an embryo is visible (a blighted ovum) or later. Trisomies 13, 18, and 21 may survive until birth. ...Read more

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What is trisomy 22?

What is trisomy 22?

Trisomy 22: Trisomy is a big word that really only means three copies. Trisomy 22 means three copies of chromosome 22. Trisomy 22 causes many spontaneous pregnancy losses. If a fetus has trisomy 22 it rarely survives into the second or third trimester. If born alive, the newborn usually dies. ...Read more

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What is trisomy 13?

What is trisomy 13?

Chromosome error: Humans have 23 pairs of chromosomes(c) making up our dna.When the egg or sperm form, the (c) pairs are supposed to split up with 1 (c) of each pair going to the egg or sperm.If the 13 (c) does not split & both go into an egg, fertilization will add a 3rd from dad & a trisomy 13 will begin to form. The imbalanced (c) causes malformations, miscarriage or early death. ...Read more

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What does trisomy 20 non mosaic mean, my son had this and died at 7 weeks gestation ?

What does trisomy 20 non mosaic mean, my son had this and died at 7 weeks gestation ?

Extrachromosome: This means your fetus had 3 copies of the number 20 chromosome, and no evidence of any tissue with the normal 2 copies.Chromosomes carry the instructions that tell the fetus how to form its organs and tissues. When an extra one shows up, it causes confusion in that process and many will miscarry. A few combinations like trisomy 21 can be born but have predictable health problems through life. ...Read more

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Can you please explain what Trisomy 16 is and list the symptoms for me? Thank you.

Can you please explain what Trisomy 16 is and list the symptoms for me? Thank you.

Trisomy 16: Trisomy 16 is a fetus w/ three copies of this chromosome instead of the usual 2. It is responsible for almost 10% of miscarriages in the US. Although full trisomy 16 is not compatible w/ life, there are children born with partial trisomy 16. These children have heart and vascular problems, delayed growth, speech and physical development, reproductive disorders and kidney problems. Trisomy16.org ...Read more

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What people with trisomy get dementia?

Down's syndrome: Down's syndrome involves a trisomy of the 21st chromosome, or an extra copy of chromosome 21. People with down's syndrome have a higher risk of developing dementia earlier. ...Read more

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What could cause trisomy 21? Other than translocation? And maternal age?

What could cause trisomy 21? Other than translocation? And maternal age?

Nondisjunction risk: You mentioned the two known risk factors for trisomy 21. Increasing maternal age has an increased risk of nondisjunction (the failure of homologous chromosomes to separate during and after meiosis). This leads to an extra copy of chromosome 21 in the egg. There are probably genetic mutations that lead to increased nondisjunction, but these have not been discovered yet. ...Read more

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What is edwards syndrome (trisomy 18) like?

Extra chromosome: In trisomy 18 the patient has an extra chromosome 18. This genetic disorder frequently causes heart and kidney defects. They may have a small head and jaw and usually have severe developmental delay. Here is a link http://www.Trisomy18.Org/site/pageserver?Pagename=whatist18_whatis. ...Read more

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What is edwards syndrome (trisomy 18)? What causes it?

Extra chromosome: In trisomy 18 the patient has an extra chromosome 18. This genetic disorder frequently causes heart and kidney defects. They may have a small head and jaw and usually have severe developmental delay. Here is a link http://www.Trisomy18.Org/site/pageserver?Pagename=whatist18_whatis. ...Read more

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What's the relationship between trisomy 21 and down syndrome?

What's the relationship between trisomy 21 and down syndrome?

Name game: Dr.Langdon Down worked at a home for the retarded in Britain in the 1800's.He was credited for the first published description of the syndrome that would carry his name. After the human chromosomes were identified and numbered in the 1950's, DS was studied and trisomy 21 was identified in most. Later studies show an extra piece of a specific area of the 21 is all that is needed to have DS. ...Read more

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What is patau syndrome, a trisomy?

What is patau syndrome, a trisomy?

Trisomy 13: Patau syndrome is also called trisomy 13. It occurs when a baby has 3 copies of the number 13 chromosome instead of the usual 2 copies. It causes severe physical problems and most babies with trisomy 13 die before birth or within the first year after birth. It usually happens because of an accident which occurs when the egg is fertilized, and occurs more commonly as mothers get older. ...Read more

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What are the effects of trisomy 17 ?

What are the effects of trisomy 17 ?

See below: It's a rare genetic disorder where duplication of genetic material from chromosome 17 causes various abnormalities. The type and severity of symptoms varies depending on the size and location of the genetic material that is duplicated. Possible symptoms: •impaired intelligence •developmental delay •reduced muscle tone •various facial anomalies •short stature. ...Read more

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What is another name for trisomy 21?

Down Syndrome: This syndrome was named for j langdon down, a physician who ran a foundling hospital in britain many years ago. He wrote up one of the first recognized descriptions of the common features of the syndrome published in a medical journal. ...Read more

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What are the differences between trisomy 21 and xxx?

What are the differences between trisomy 21 and xxx?

Completely different: Down syndrome (trisomy 21) is characterized by varying degrees of neurodevelopmental delay (mild to severe) propensity for dementia at early age and heart/blood disorders, but may have a near normal life span. Extra chromosome x is usually very mild condition; affected females tend to be tall and have relatively small heads and minimal decrease in their verbal and performance iq scores. ...Read more

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What're the causes of trisomy 18?

Error in formation: During the formation of the egg or sperm, the chromosome(c) pairs split with one of each going to the egg or sperm. At conception, the egg & sperm each bring 1 of each (c) & the embryo starts with a pair of each.If there is an error & the 18pair doesn't split but donates a pair of 18's to the egg, then it picks up a 3rd from the sperm. Age/toxins/radiation etc all may play a role in (c) errors. ...Read more

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What population is affected by trisomy 13?

What population is affected by trisomy 13?

?? odd question ??: Humans of any race, culture,ethnic group, social status, etc. can have a baby with trisomy 13. ...Read more

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What are the odds of trisomy 18 with 4 cysts, short finger and a cleft lip/palate?

What are the odds of trisomy 18 with 4 cysts, short finger and a cleft lip/palate?

Odds Not Great: The symptoms given can be found with several congenital chromosomal anomalies & do not point specifically to Trisomy 18. Palatal cleft is more commonly seen with Trisomy 13, Short fingers are commonly seen with Trisomy 21. Type of "cysts" is not given. Each Trisomy has reconizable features but there is overlap. A detailed exam by Pediatrician or Geneticst is needed to assess these findings. ...Read more