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Doctor insights on: What Is The Sequence Of Seroconversion Of Hepatitis B Markers

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What is the sequence of seroconversion of hepatitis b markers?

What is the sequence of seroconversion of hepatitis b markers?

See below: First you will see hepatitis b virus dna and surface antigen. E antigen will also show up around this time. Next will be core IgM and then total core antibody and hep e antibody. After several months you develop surface antibody. This is for someone that clears the virus. ...Read more

Seroconversion (Definition)

This normally refers to be positive to a test. This happens when the host have low amount of antibodies in serum and test is initially negative then they became positive due to the increased immunity ...Read more


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What's the significance of hepatitis b immunoglobulins?

What's the significance of hepatitis b immunoglobulins?

Post-exposure : Prophylaxis. Hep b Immune Globulin is given following exposure to hep b to prevent infection. It should be followed three weeks later with hep b vaccine. ...Read more

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What is the latest development of hepatitis b treatment?

What is the latest development of hepatitis b treatment?

Antivirals: The most commonly used antiviral medications against hepatitis b are Entecavir and tenofovir. Both are well tolerated and do a great job stopping the hbv from making copies of itself. No medications cure hepatitis b so many people have to take them indefinitely. Gilead is working on an immune enhancer drug that might help control hbv as well as a tenofovir-like drug with fewer kidney problems. ...Read more

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What is the percentage of perinatal transfer of hepatitis b virus in the vaccine era?

What is the percentage of perinatal transfer of hepatitis b virus in the vaccine era?

Where?: With use of the vaccine there is marked reduction in the incidence of chronic hep b carriage which is generally how perinatal transfer occurs. In taiwan, for example, the rate has fallen dramatically. In third world countries it remains inordinately high since access to the vaccine or acceptability by the population is reduced. Check the who web site for exact percentages by country. ...Read more

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What are the probable symptoms of hepatitis b in a drug user?

Sometimes no symptom: Hep b is a virus which can cause liver disease, including liver failure, but often shows no symptoms for years, even though it is doing damage. Symptoms can be vague: nausea, fatigue, decreased appetite, changes in skin coloring, abdominal pain. Hep b is detected by a blood test, and if you don't carry the virus, you can get a vaccine against it. Hep c is similar, but deadlier & no vaccine yet. ...Read more

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What are the symptoms of a reaction to hepatitis b vaccine?

What are the symptoms of a reaction to hepatitis b vaccine?

See below:: The majority of people who receive the Hepatitis B Vaccine (65%) do not experience any reactions to it. About 3% of those immunized will develop pain and tenderness where the shot was given; low-grade fever occurs in about 1% to 6% of vaccine recipients. Serious reactions are "extremely rare." in far less than 1 out of 10, 000 shots given, or about .001%, a serious allergic reactions may occur. ...Read more

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What are the cases of the activation of B lymphocytes ?

What are the cases of the activation of B lymphocytes ?

A symphony: Hi. Activation of Blymphocytes is a symphony involving exposure to relevant antigen, macrophages, T lymphocytes, and other immune system cells. A beautiful process. ...Read more

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What are the effects of hepatitis b usually?

What are the effects of hepatitis b usually?

Varies: Hbv can cause acute hepatitis that can range from asymptomatic to fulminant. Outside the neonatal period, 5-10 percent become chronic and some of these develop cirrhosis and can result in liver cancer but...Good news, there is a vaccine to prevent it and medications that can be used to treat it. ...Read more

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What is the course of duration of peginterferon(interferon alfa2b) in the treatment of hepatitis b? Plz explain in detail.

What is the course of duration of peginterferon(interferon alfa2b) in the treatment of        hepatitis b? Plz explain in detail.

Hepatitis B: Interferon Alfa 2b can be used for treatment of CHRONIC hepatitis B. It is not for acute Hepatitis B which often resolves spontaneously. The dose for chronic hep B is 10 mill units subcutaneous or IM shot 3times/week for 16 weeks, or 5 mill units daily for 16 wk. get with your doctor to see if you have the chronic form of hepatitis. Good luck! ...Read more

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What are the indications of using interferon alpha in case of viral hepatitis?

Progressive HCV: Although i was a coauthor on the first report of using interferon for hepatitis b, there is now oral and more effective therapy. It, so far, is still used in combination with other therapy for progressive hepatitis c based on a variety of parameters including liver biopsy and certain blood tests. Many, perhaps most people with chronic hcv die with it but not of it. ...Read more

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What is the accuracy of the RNA HIV test?

What is the accuracy of the RNA HIV test?

Not for diagnosis: It's very useful for monitoring the response to hiv, and it's accurate to diagnose or rule out acute HIV infection in someone with symptoms, but for simply diagnosing HIV infection, the HIV serology (antibody test) is better. That's because people who aren't infected can have false positive RNA tests, and people who are positive can have false negative RNA test. ...Read more

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What is the degree of accuracy of an nse (neuron specific enolase) blood test?

What is the degree of accuracy of an nse (neuron specific enolase) blood test?

Depends on the : Purpose of the test. Nse is one of the tumor markers. Such tests are not very useful for diagnosing tumors but are useful for monitoring the course of the disease. See this site for more info. http://www.mayomedicallaboratories.com/test-catalog/clinical+and+interpretive/80913. ...Read more

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What is hepatitis b surface antigen in general?

What is hepatitis b surface antigen in general?

Infection is active: If you are surface antigen postive = protein on the surface of the virus is in its active form which is still floating in your blood and indicates active/on going infectious state. This protein triggers body to produce antibody which can help rid off the infection or preventing it as in case of hepb vaccines. In your case, no antibody or not enough to rid of the antigen. Consult doc. Good luck. ...Read more

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Explain why the accuracy of RNA transcription is not critical as the accuracy of DNA replication?

Explain why the accuracy of RNA transcription is not critical as the accuracy of DNA replication?

DNA is THE proof: In dna & RNA hierarchy , the dna the master replicates, basis of inheritance ( and propagation) RNA replicates particular segment, as gene expression & proof reading mechanism, copied so the replication of dna is important than RNA transcription. ...Read more

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What are the life spans of the tetanus detecting memory b cells?

What are the life spans of the tetanus detecting memory b cells?

Booster at ten years: While i cannot answer your question specifically, it is good to get a booster dose of tetanus vaccine every ten years. ...Read more

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What's the meaning of hepatitis be ab reactive?

What's the meaning of hepatitis be ab reactive?

Depends: The presence of antibody against hepatitis b surface antigen indicates affected individual is protected against hepatitis b, usually through hepatitis b vaccination. However, the presence of antibody against hepatitis b core antigen indicates an active hepatitis b infection. ...Read more

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What are the physical manifestations of hepatitis?

Hepatitis symptoms: In cases of acute hepatitis you usually have an acute illness with low grade fever, mild abdominal discomfort, fatigue, achiness, and your eyes and skin may turn yellow in the acute phase (jaundice), (and your urine darker. In the chronic phase, about 10%, there are usually no symptoms till many years later, which are then caused by the development of cirrhosis and the loss of liver function. ...Read more

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My result of laboratory test is reactive for hepatitis b, what is the meaning of that?

Depends : It all depends on what hepatitis b tests are reactive. It at least shows you have been exposed to HBV or have recheieved the vaccine. If you have antigen detected in the serum , it is more consistent with active disease. ...Read more

Dr. Jay Park
1,191 doctors shared insights

Hepatitis (Definition)

Inflammation of the liver, which can be caused by many things, such as alcohol overuse, excess sugar consumption, viral infections, autoimmune disorders, certain medications, ...Read more


Marker (Definition)

A "marker" is a protein or enzyme that can represent a disease process. Some markers are specific for a particular disease, while ...Read more