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Doctor insights on: What Is The Result Of Fathers Blood Type Homozygous D In Rh Isoimmunization

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Can you tell me in the ABO blood group, which allele is considered recessive?

Can you tell me in the ABO blood group, which allele is considered recessive?

ABO blood type: In this system of red cell antigens, O is considered to be recessive. Someone with type O blood would have two O alleles. People with type A blood can have two A alleles or one A allele and one O allele. Same with blood type B. This makes O the recessive and A and B are dominant. ...Read more

Dr. Jeffrey Wint
19 doctors shared insights

Mother Baby Blood Type Mismatch (Definition)

Mother Baby Blood Type Mismatch, also known as ABO incompatibility, occurs when a pregnant mother has a different blood type than the developing baby. Exposure to the baby’s blood type, either from that pregnancy or a previous sibling, causes the mothers body to develop antibodies to the blood type. The condition is dangerous as antibodies can cross the placenta and cause anemia (blood cell destruction), jaundice, or fetal ...Read more


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What is expected when a man of a+ and woman of o rh+ produces an offspring ? Could this translate to any complications in terms of blincompatibilit

What is expected when a man of a+ and woman  of  o rh+ produces an offspring ?  Could this translate to any complications in terms of blincompatibilit

ABO: You are a+, the woman is o+. Women who are o+ carry anti-a and anti-b antibodies. The child will either be a+ or o+. If the child is a+, there is a chance that mother's anti-a antibodies will be high and cross the placenta and cause red cell break down. This doesn't affect the baby in utero but may cause high bilirubin levels (or jaundice) in the new born. ...Read more

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Is there a genetic test in UK that can tell if a person is a poor metabolizer with Clopidogrel having two copies of each of the CYP2C19 gene.?

Is there a genetic test in UK that can tell if a person is a poor metabolizer with Clopidogrel having two copies of each of the CYP2C19 gene.?

Phenotype is the big: issue, not genotype, because we each live with the complex results of both genotype combined with all our complex internal controls, beyond the any gene or sets of genes alone. Since clopidgrel is a platelet suppressing, clot-slowing agent, best check clotting with & without whatever trial dosage. The best of the clotting tests is TEG, study: Thromboelastography, commonly used in hospitals. ...Read more

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What is the health implication and risk of sc blood genotype woman?

What is the health implication and risk of sc blood genotype woman?

Clarification: Are you asking what is the implication of having the sickle cell? A woman can have one gene for sickle cell and this makes her a carrier. Typically carriers who are heterozygous for the disease are asymptomatic. Or, she can have 2 genes (one from each of her parents) of the sickle cell gene and that typically will make her have sickle cell disease. I'm not sure if that answers your question? ...Read more

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Rh negative and not sure who the baby's father is. Odd are Rh positive like 85% of the population, right?

Rh negative and not sure who the baby's father is. Odd are Rh positive like 85% of the population, right?

Correct: Because you are rh negative, you should be offered Rhogam at 28 weeks and after delivery if the baby is rh positive. Also, there are some other situations where Rhogam may be given, but they are less common. ...Read more

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"Is Panaromic blood test to find the gender of the baby with just 6.78% of fetal fraction cells accurate in detecting the gender of the baby as boy."?

"Is Panaromic blood test to find the gender of the baby with just 6.78% of fetal fraction cells accurate in detecting the gender of the baby as boy."?

Panoramic: It is told to be 99% accurate. But I have heard of false negatives....purpose is to look for genetic defects. Gender is bonus! ...Read more

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What can you mean if the result of g6pd in newborn screening is deficient?

What can you mean if the result of g6pd in newborn screening is deficient?

More information nee: Infant my have increased bilirubin (jaundice) or may also have infection and anemia. Infant may also be normal. Check with baby's physician! ...Read more

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What is the different between the blood group "a Rh 'd' positive" and "o Rh 'd' positive"?

What is the different between the blood group "a Rh 'd' positive" and "o Rh 'd' positive"?

Group A and O: The different is one has blood group o+ - and the other has blood group a+. Group o has no antigen a and b, but has antibody to a and b. So, group o is a universal donor- and the blood can be given to people with different blood group. Group a has antigen a, and antibody b. So, can receive group a or o blood. Group o only can receive blood group o if needed any blood transfusion. ...Read more

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Is a woman with sc blood genotype a sickle cell carrier or patient. And what is the health implication of this especially during pregnancy?

Is a woman with sc blood genotype a sickle cell carrier or patient. And what is the health implication of this especially during pregnancy?

Hgb SC: Is a sickle cell syndrome but the genetics are different. A woman with HGB sc will pass either a HGB s gene, or a HGB c gene to her child. It is important to know what kind of HGB the father has-he should have a hemoglobin electrophoresis to find out how the child might be affected. Pregnancy complications are rare, but the baby can have a low weight, and rarely there are complications for the mom. ...Read more

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What is the likelihood of a false negative herpes type specific blood test with background of lupus (sle)?

What is the likelihood of a false negative herpes type specific blood test with background of lupus (sle)?

About 0% to 9%: Quest diagnostics' website states that their herpes type-specific IgG antibody test is 91-100% sensitive, so there are a few false negative results. A repeat test can be done 4-6 weeks later, if worried about a false negative. Lupus should not affect the result, but if a person is on strong immuno-suppressive therapy, his antibody production may be blocked, which may make test results unreliable. ...Read more

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Please specify the test for detecting carrier genes in case of haemophilia.

Please specify the test for detecting carrier genes in case of haemophilia.

Hemphillia: Genetic testing is also available for the factor viii gene and the factor ix gene. Genetic testing of the fviii gene finds a disease-causing mutation in up to 98 percent of individuals who have hemophilia a. Genetic testing of the fix gene finds disease-causing mutations in more than 99 percent of individuals who have hemophilia b. Genetic testing is usually used to identify women who are carriers. ...Read more

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35 week of pregnancy, antibody anti-e (1:8).My blood group:ab ccd.Ee(rh pos), father b+.What does it mean?Why should we test the antogen of the father?

35 week of pregnancy, antibody anti-e (1:8).My blood group:ab ccd.Ee(rh pos), father b+.What does it mean?Why should we test the antogen of the father?

Rh is complicated: Anti-e ("anti big-e") is much less likely to be troublesome than anti-d (the common anti-rh antibody). You inherited two copies of the cde allele, one of several that you can get at your main rh locus, and the father of at least one of your children has at least one copy of an allele with a big e. Titer isn't so important as how junior seems to be doing before birth. Best wishes. ...Read more

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Is there any genetic condition that would require testing of the father of the fetus? We used a donor.

Is there any genetic condition that would require testing of the father of the fetus? We used a donor.

Screening: Autosomal recessive conditions are genetic diseases where risk is present when both parents have an abnormal gene. An example is cystic fibrosis, where parents who both carry an abnormal gene have a one in four risk for having a child who has cystic fibrosis. ...Read more

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The blood of choic for an exchange transfusion of an ABO hdn in a b-postive baby.. Is it o or b postive packed or whole blood..?

The blood of choic for an exchange transfusion of an ABO hdn in a b-postive baby.. Is it o or b postive packed or whole blood..?

Your doc knows: Usually it's reconstituted packed rbc with fresh frozen plasma, o neg, but it may be a whole blood as well (depends what is available, reconstitution of PRBC takes time). ...Read more

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My father has a rare type of sickle cell that affects his WBC's instead of RBC's. Is there any information on this type of Sickle Cell Trait?

My father has a rare type of sickle cell that affects his WBC's instead of RBC's. Is there any information on this type of Sickle Cell Trait?

Get better info: Your dad may have a white cell disorder but it has nothing to do with sickle cell trait which is a specific red cell disorder. You need to consult with your day and find out the proper name for his disorder before we can comment. A doc may have compared it to sickle cell trait to try to explain it. ...Read more

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Is the Rh factor in blood an antibody or antigen?

Is the Rh factor in blood an antibody or antigen?

Antigen: Rh factor is one the antigens present on red cells. Actually there are a number of subtypes of rh but the one people refer to is rh d antigen. See this site for more info. http://www.ncbi.nlm.nih.gov/books/nbk2269/. ...Read more

Dr. Linda Callaghan
90 doctors shared insights

Blood Type (Definition)

Refers to the proteins present or not present on the surface of red blood cells. The types are a, ...Read more