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Doctor insights on: What Is The Relationship Between Vitamin Deficiency And Pernicious Anemia

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What is the relationship between vitamin deficiency and pernicious anemia?

What is the relationship between vitamin deficiency and pernicious anemia?

It's the cause: Pernicious anemia is caused by vitamin B12 deficiency, which is most commonly caused by lack of intrinsic factor, which is a protein that's made in your stomach. Other causes of low B12 and other vitamin deficiencies can cause a nearly identical anemia, but then they are not called "pernicious" anemia. ...Read more

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Pernicious Anemia (Definition)

It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily ...Read more


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Positive mthfr heterozygous after multiple miscarriages, known pernicious anemia, what is the likelihood of having other b vitamin deficiencies?

Positive mthfr heterozygous after multiple miscarriages, known pernicious anemia, what is the likelihood of having other b vitamin deficiencies?

Not more likely but: Pernicious anemia is due to problems absorbing B12 but doesn't interfere with absorbing other vits.Mthfr mutations mean you have trouble converting Folic Acid to the active form, so take l-5-mthf.Genes don't affect absorption of other b vits but due to genetics some require higher amounts of b's than others-your other issues don't mean you're more likely to have this but it's safe to try b complex. ...Read more

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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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What is a recommended diet for someone with hypothyroidism, hypercortisolism, pernicious anemia, and a vitamin d2 deficiency?

What is a recommended diet for someone with hypothyroidism, hypercortisolism, pernicious anemia, and a vitamin d2 deficiency?

Nutrient dense foods: Eat foods that are nutrient dense (like meat, fish, poultry, eggs, cheese, low starch vegatables and water) avoid foods that are not nutrient dense (like starches and sugars, including fruit) nutrient dense foods will increase your basal metabolic rate. On the other hand, starches and sugars impair thyroid metabolism via affects on your liver (which helps activate thyroid hormone). ...Read more

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Please what's the difference between pernicious anemia and vitamin B12 deficiency.my iron levels are perfect.I'm getting injections for vitamin b12.

Please what's the difference between pernicious anemia and vitamin B12 deficiency.my iron levels are perfect.I'm getting injections for vitamin b12.

Intrinsic factor: Vitamin B12 is present in meat and animal protein foods. Absorption of B12 occurs in the intestine (ileum) and requires intrinsic factor (IF), made by stomach cells. In pernicious anemia, IF production is deficient, and results in anemia, a reduction in hemoglobin/hematocrit. One can be vitamin B12 deficient without becoming anemic and/or without having deficient IF. Best wishes:) ...Read more

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I have vitamin B12 Deficiency not pernicious anemia. My doctor told me. My reading was 160. What is that number is it 160mcg.

I  have vitamin B12 Deficiency not pernicious anemia. My doctor told me. My reading was 160. What is that number is it 160mcg.

It's on your report: the lab report should have a reference value. sometimes it is reported as nanograms per milliliter (ng/mL), or as picograms per milliliter (pg/mL) 1 picogram is equal to 0.001 nanograms, making the nanogram a larger unit. when you take b12, the dose is usually in micrograms (mcg) 1 mcg is equal to 1000 nanograms i had to look up all that, by the way ...Read more

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Hi I have vitamin B12 Deficiency. Doc didn't say pernicious anemia. Everyone said I'm going to get cancers.god im so scared. I've started injections?

B12 def: Are you vegetarian or vegan, they have B12 issues at times because B12 sources are animal. May also be ileitis or intestinal issues where B12 is absorbed ( if not pernicious anemia) or dietary/ age. If you are on injections and you level are adequate ( I like above 400) I would not be concerned ,don't worry ...Read more

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My doctor has told me I do not have pernicious anemia. I have vitamin B12 Deficiency.blood test result was 160. So I have mild vitamin B12 Deficiency?

Get a consult: "Mild vitamin B12 deficiency" is like being "a little bit pregnant." It should not happen -- ESPECIALLY if you are, as you say, pregnant. If this happened because you are a vegetarian, reconsider or start supplementing now. Otherwise, you have a right & duty to know what's happening. Your primary care physician didn't communicate answers to you -- a 2nd physician's input is in order. ...Read more

Dr. Steven Ginsberg
1,236 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


Dr. Randy Baker
1,567 doctors shared insights

Vitamin Deficiency (Definition)

Vitamin deficiency is a symptom in which a person has lower than normal levels (on blood testing) of one or more vitamins, usually due to not eating a good diet. Some medical conditions decrease the absorption of vitamins from food, even if ...Read more