Doctor insights on:
What Is The Pros And Cons Of The Medication Xeloda
See below: Xeloda can shrink tumors in 3-4 weeks time. It would rarely cause bleedding in the vomitus...It could only happen if it has caused severe mouth/throat ulcerations which is uncommom but it does occur in 1-2% of the patients taking xeloda. ...Read more
Mcrc patient aged 65. Drs not willing to
Give any 5-FU drugs due to chest tightness . Tried Xeloda n irinotecan . What can we do now ?
Define met site.: Regardless of site and extent of mets, primary resection essential. This eliminates any other site of spread. PET/CT will determine met areas after primary removed. If as is usual, mets are to liver, microwave ablation, or chemo embolization or radioactive microspheres given to liver to control disease. Any pulmonary nodes removed thru thorascope. Most protocols contain 5FU. ...Read more
Can any targeted therapies or other drugs help with metastic colon cancer when Xeloda n irinotecan has failed ?
Yes: Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept. FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available. ...Read more
In certain cancer: Xeloda is an oral chemo, which is a prodrug of 5-fluorouracil- a type of chemotherapy that has been used for many different cancers. Xeloda is an effective chemotherapy for some cancers- such as gastrointestinal cancers ( colon, rectal, stomach, esophageal etc), breast cancer- but not for all type of cancer. ...Read more
An Oral Chemotherapy: Xeloda is an oral chemotherapy drug, the most common side effects are diarrhea, nausea, hand-foot syndrome (redness, swelling, cracking of palms/soles) and like any chemotherapy may bring down your white blood cells. To prevent this you may take an anti diarrheal, anti emetic, b6, use a skin moisturizer and check your blood frequently. Not everyone experiences one of these symptoms. ...Read more
Not sure: I am not sure about your question. I think that you are asking how long it stays in the system after 6 months of use. A typical schedule in 2 weeks on and 1 week off. The drug is quickly eliminated from the body. Kidney disease can affect the elimination. Side effects in the skin of hands and feet can take a few weeks to heal after the drug is stopped. If not helpful clarify the question please. ...Read more
Four companies..: Sorry to hear that you will need xeloda..I assume you have colon cancer? True dpd is quite rare and so routine screening is not recommended, but if you need to, your doc can order it and four comapnies do this: entrogen, myriad, labcorp, and molecular diagnostics laboratories are the current ones.. Good luck to you.. ...Read more
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