Doctor insights on:
What Is The Pathophysiology Of Anemia
Decr brain bloodflow: Syncope (loss of consciousness) is caused by reduced blood flow to the brain. Most cases are cardiogenic in nature (for example, arrhythmias), but other causes can include vasovagal response, carotid artery compression, vertebrobasilar system disease, etc. See your primary care provider for further discussion if you've experienced syncope. http://www.ninds.nih.gov/disorders/syncope/syncope.htm ...Read more
Many: Hypotension or low blood pressure can happen for a variety of reasons. Acute illness (i.e. Sepsis), adrenal gland insufficiency, overmedication, heart failure are just a few of the many reasons for low blood pressure. Additional causes can be volume depletion (orthostasis), or a variety of neurocardiogenic causes such as pots or similar. ...Read moreSee 1 more doctor answer
High insulin: Very common cause of hypoglycemia is high Insulin levels (almost always related to excess sugar and carb intake). Initially the high Insulin causes a reactive hypoglycemia, however over time, the chronically high Insulin levels lead to "insulin resistance". When your Insulin no longer works your blood sugars will rise and you develop diabetes. This is 100% preventable wi proper diet. ...Read moreSee 1 more doctor answer
Several: Hemoglobinopathies and enzymopathies are the most common anemias that are hereditary, such as sickle cell anemia, hemoglobin c disease, thalassemia. Absorbtion prorblems can also have a familial predisposition, such as vitamin B12 or iron defficiency. All of these should be able to be easily worked up by a physician, often largely simply by looking at a periferal blood smear. ...Read more
Macrocyte/hypochromi: macrocytes. causes. B12/folate deficiency. or liver disease or myelodysplastic syndrome hypothyroidism,and increased number of reticulocytes as in hemolysis or if agglutinations of RBC may give false high MCV.hypochromia low hgb in the RBC may be low iron .anemia of chronic disease ...Read more
Black out or more: Hello there - anemia is reduction in red blood cell (rbc) count - and specifically reduction in hemoglobin concentration which is the oxygen carrying agents in the RBC - and yes, anemia will cause hypotension because the blood is thinner and the oncotic pressure (viscosity or concentration pressure) is down - so this compounded effects of low blood pressure and low oxygen carrying capacity is bad. ...Read moreSee 2 more doctor answers
Mostly obesity: There are two kinds of diabetes. Type 1 is a genetic accident, or bad luck. It comes on in childhood usually and is a lack of insulin. Type 2 is more likely with a family history, but is strongly tied to obesity. It is caused by a resistance to Insulin initially, rather than a lack of it. I have seen diabetes type 2 go away with enough weight loss. ...Read more
Either: Caused by either hereditary genetic mutations or the following theories.A possible cell defect in the sutires themselves that leads to early fusion.When in the womb, the baby assumes an irregular position.If pressure was being put on the baby's head, the plates of bone in the skull might be pushed together & caused the sutures to fuse. ...Read moreSee 1 more doctor answer
Rhythm restoration: Assuming the problem is ventricular fibrillation, the chaotic and fatal cardiac arrhythmia, one must know there are hierarchies of pacemakers controlling the heart rhythm (fastest one usually wins). By shocking the heart into functional standstill, the next available fastest stable pacemaker tissue takes over, usually sinus node > ectopic atrial > junctional > idioventricular/purkinje. ...Read moreSee 1 more doctor answer
Many causes: Hypotension can be caused by many causes - sometimes it is normal, other times by medications or metaboloic conditions such as low thyroid. Hypotension causing shock can be hypovolemic (from loss of blood), cardiogenic (heart function not working well), obstructive (pulmonary embolism causing blood vessel obstruction), or distriubutive (think sepsis, low adrenal function, anaphyaxis, toxins). ...Read more
Very challenging: Porphyrias are life-long diseases with symptoms that come and go. Some forms of the disease cause more symptoms than others. Proper treatment and avoidance of triggers can help prolong the time between attacks. But attacks are quite painful and can be fatal. Life is a real struggle for someone with porphyria but it is possible to even do great things - some historical figures have suffered it. ...Read more
Rheumatic fever: Rheumatic fever is caused by a streptococcal infection triggering a specific immune response. Acutely various joint aches and pains occur accounting for the 'rheumatic' term. Long term the mitral and/or aortic valves are often involved with chronic inflammation and damaged. We see rf rarely in the us now, but sometimes in new immigrants. ...Read more
Genetic mutation: Disease of plasma cells or b cells in which inadequate ( very low or none) amounts of antibodies (globulin) of the gamma type are produced . The cause is primarily an x linked genetic mutation. ...Read more
Genes, environment: This answer will change as we know more about lupus. We believe that for a person to get lupus, from the limited genetic information we have now, about 10% is from known genetic causes and remaining 90% unknown genetic causes and environmental causes. Environmental causes are largely undefined but important. Think about this: only 30% of identical twins develop lupus together. ...Read moreSee 1 more doctor answer
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