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Doctor insights on: What Is The Pathophysiology Of Abdominal Aortic Aneurysm

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What is the pathophysiology of abdominal aortic aneurysm?

What is the pathophysiology of abdominal aortic aneurysm?

Inflammatory process: The exact mechanism for AAA formation is not known. There are several etiologies/theories. The most widely accepted is that aaas form due to an inflammatory process in the wall of the aorta associated with atherosclerosis. Inflammatory cells are thought to degrade structural proteins (such as elastin) in the wall of the aorta, weakening it and allowing for aneurysm formation. ...Read more

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Dr. Mario Matos-Cruz
945 doctors shared insights

Aortic Aneurysm (Definition)

"Aneurysm" has scary implications for many people. It just means an enlargement of an artery. The problem is that when arteries (including the aorta) get too large, their walls become weak and prone to tear (dissection) or rupture. If this happens in the aorta it can be a catastrophe. Management of aortic aneurysms depends on where it is, how big, whether it's growing, ...Read more


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What is the mortality rate of abdominal aortic aneurysms?

What is the mortality rate of abdominal aortic aneurysms?

AAA: Onceit reaches 5.5 cm diameter, then the risk of rupture with almost certain death is less than the risk of repair of the aneurysm. ...Read more

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What is the post-operative care of abdominal aortic aneurysm?

Depends: There is a big difference between an open repair and an endovascular repair. Open repairs require aggressive cardio-pulmonary resuscitation post-op. Depending on the extent of the repair patients are often kept intubated the first night. Endovascular procedures are typically less of a physiological burden on the body and patients are extubated the same day and typically go home the next day. ...Read more

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What are the symptoms of an abdominal aortic aneurysm?

What are the symptoms of an abdominal aortic aneurysm?

Usually none: Most of AAA have no symptoms and discovered by routine physical exams, screening ultrasound or incidental finding on ct scans. If symptomatic then usually pain in upper to mid abdomen sometimes radiating to the back or just back pain , rupture with severe pain and shock , sometimes present as clots traveling to the legs with acute pain or blue toes. Rare type is infected or inflammatory /fever. ...Read more

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What is the largest abdominal aortic aneurysm repaired?

What is the largest abdominal aortic aneurysm repaired?

Largest AAA repaired: You shouldn't think about it as, " is it too big to repair?" many anatomic details as well as a person's overall medical condition go into the decision as to if an aneurysm can be repaired. Its overall size is not a main consideration (though if its still small, they can usually be watched without repair). ...Read more

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What is the mortality rate for abdominal aortic aneurysms?

What is the mortality rate for abdominal aortic aneurysms?

Very high if rupture: Rate of rupture: 5 to 6 cm is 5 to 15%; 6 to 7 cm 10 to 20%; 7 to 8 cm 20 to 40%. Also if the aneurysm increases in size by 8 mm in a year the risk of rupture is high even if less than 5 cm. Hence not only is attention paid to the size but also the rate of growth. Once it ruptures the mortality rate is greater than 50%. The key is to repair before rupture either by surgery or stent graft. ...Read more

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What sort of problem is an abdominal aortic aneurysm?

Dilation: It is a swelling or dilation of a vessel due to weakness in the wall of the vessel (aorta). The concern is the risk for rupture, which can cause severe pain and massive bleeding. ...Read more

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What is coarctation of the aorta?

What is coarctation of the aorta?

Narrowing of alrta: Coarctation is a narrowing of the main vessel (aorta). It leads to hypertension and increased work for the heart. Untreated it leads to stroke coronary disease and death. Therapeutic options are surgery or catheter therapy. ...Read more

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What are the symptoms of an aortic aneurysm?

Typically non: Most of them are asymptomatic. Abdominal aortic aneurysm can cause mid abdominal and back pain sometimes. Severe pain and fever if infected. Unusually emboli or clots to legs and ischemia. Thoracic aortic aneurysm may cause back pain, or compression on structure like esophagous(difficulty swallowing), trachea or bronchus( difficulty breathing) or nerves like recurrent laryngeal nerve( horesness). ...Read more

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What is the presumed cause of most aneurysms of the abdominal aorta?

What is the presumed cause of most aneurysms of the abdominal aorta?

Several theories: Most common belief is that aneurysms develop due to some inherent weakness in the artery's muscular layer due to an imbalance of collagen metabolism or genetic collagen abnormalities. The only independent risk of aneurysm growth is high blood pressure and smoking. ...Read more

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What are the symptoms of aortic aneurysm?

Depends: You may not have any symptoms from an aneurysm until it is too late. If you have a family history or even a suspicion of having an aneurysm it is worth having this checked. ...Read more

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What are the signs are of an abdominal aortic aneurysm?

Signs of AAA: There frequently are no signs at all which is why screening ultrasound programs exist to pick them up in higher risk individuals. Some people my report feeling their "heartbeat in their belly". Unusual belly or back pain may also be symptoms. ...Read more

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What is the typical underling cause for aortic aneurysm?

What is the typical underling cause for aortic aneurysm?

Arteriosclerosis: Most arteriosclerotic aneurysms result in cystic medial necrosis of the aorta resulting in dilatation of the artery secodary to the internal pressure and weakness of the arterial wall. Any part of the aorta and its branches may be affected. Infections with bacteria, fungus, syphillis may also produce aneurysms in the aorta. ...Read more

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Dr. Laura Pak Dr. Pak
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What are causes of an aortic aneurysm?

Dr. Laura Pak Dr. Pak
4 doctors agreed:
What are causes of an aortic aneurysm?

Several things: About 5% of men over the age of 65 have abdominal aortic aneurysms. Risk factors include: increasing age, male sex, family history of aneurysm (may increase your risk 4-fold), hypertension, and history of smoking. Dissecting aneurysms can be caused by localized damage to to the artery from hypertension or trauma (deceleration or sheering-type injury) or catheter injury from an angiogram. ...Read more

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What is the best method of prevention to AAA (acute abdominal aneurysm)?

What is the best method of prevention to AAA (acute abdominal aneurysm)?

AAA Prevention: Key ways to prevent AAA are to increase your general health. This includes stopping smoking, controlling diseases such as diabetes and hypertension, lowering your cholesterol and eating less salt. The best treatments for an AAA come from early diagnosis with regular check ups. If found early, they can be watched until something has to be done. ...Read more

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What are the abdominal aortic rupture symptoms?

What are the abdominal aortic rupture symptoms?

AAA: read this: http://www.nlm.nih.gov/medlineplus/ency/article/000162.htm

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What is the treatment for an abdominal aortic aneurysm?

Size: Abdominal aneurysms should be treated surgically if greater than or equal to 6 cm (sometimes 5.5 cm depending on the age and risks), if symptomatic or if it grows at a rate greater than 0.5 cm/ 6 months. The treatment is endovascular repair unless the anatomy is unfavorable (unusual). You should see a board certified vascular surgeon with endovascular experience. ...Read more

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Why is the abdominal aortic aneurysm more common?

Why is the abdominal aortic aneurysm more common?

Less wall elastin : The aorta, the main artery that delivers blood from the chest to the belly, has a protein known as elastin in its wall. Smoking and COPD affect biochemistry destroying elastin, leading to weakening in the wall causing it to bulge out forming an aneurysm. Why most common in abdomen? Cause elastin layer is thickest in chest thins at renal arteries in abdomen - no surprise they often form there 1st! ...Read more

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What are the largest abdominal aortic aneurysm on record?

What are the largest abdominal aortic aneurysm on record?

Good Question: The largest abdominal aneurysm I have operated on was 16 CM in diameter. It is unusual these days to find really large diameter aneuryms due to better screening & due to the number found incidentally when exams such as sonograms or ct scans are performed for other reasons. Increasing size correlates with increased rupture rates. ...Read more

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Aorta (Definition)

The aorta is the largest artery in the body, leaving directly from the left ventricle of the heart to supply blood to the entire body. It is made of elastic tissue layers called "intima" and is subject to damage by high blood pressure, smoking, cholesterol, ...Read more


Dr. Shadi Abu Halimah
1,398 doctors shared insights

Aneurysm (Definition)

An aneurysm is an abnormally dilated blood vessel, usually defined as a diameter 2x normal or larger. As weakened vessels get larger, there is risk of potential ...Read more