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What Is The Pathophysiology Of Abdominal Aortic Aneurysm
Inflammatory process: The exact mechanism for AAA formation is not known. There are several etiologies/theories. The most widely accepted is that aaas form due to an inflammatory process in the wall of the aorta associated with atherosclerosis. Inflammatory cells are thought to degrade structural proteins (such as elastin) in the wall of the aorta, weakening it and allowing for aneurysm formation. ...Read moreSee 2 more doctor answers
"Aneurysm" has scary implications for many people. It just means an enlargement of an artery. The problem is that when arteries (including the aorta) get too large, their walls become weak and prone to tear (dissection) or rupture. If this happens in the aorta it can be a catastrophe. Management of aortic aneurysms depends on where it is, how big, whether it's growing, ...Read more
Depends: There is a big difference between an open repair and an endovascular repair. Open repairs require aggressive cardio-pulmonary resuscitation post-op. Depending on the extent of the repair patients are often kept intubated the first night. Endovascular procedures are typically less of a physiological burden on the body and patients are extubated the same day and typically go home the next day. ...Read moreSee 2 more doctor answers
Usually none: Most of AAA have no symptoms and discovered by routine physical exams, screening ultrasound or incidental finding on ct scans. If symptomatic then usually pain in upper to mid abdomen sometimes radiating to the back or just back pain , rupture with severe pain and shock , sometimes present as clots traveling to the legs with acute pain or blue toes. Rare type is infected or inflammatory /fever. ...Read moreSee 2 more doctor answers
Largest AAA repaired: You shouldn't think about it as, " is it too big to repair?" many anatomic details as well as a person's overall medical condition go into the decision as to if an aneurysm can be repaired. Its overall size is not a main consideration (though if its still small, they can usually be watched without repair). ...Read moreSee 1 more doctor answer
Very high if rupture: Rate of rupture: 5 to 6 cm is 5 to 15%; 6 to 7 cm 10 to 20%; 7 to 8 cm 20 to 40%. Also if the aneurysm increases in size by 8 mm in a year the risk of rupture is high even if less than 5 cm. Hence not only is attention paid to the size but also the rate of growth. Once it ruptures the mortality rate is greater than 50%. The key is to repair before rupture either by surgery or stent graft. ...Read moreSee 2 more doctor answers
Typically non: Most of them are asymptomatic. Abdominal aortic aneurysm can cause mid abdominal and back pain sometimes. Severe pain and fever if infected. Unusually emboli or clots to legs and ischemia. Thoracic aortic aneurysm may cause back pain, or compression on structure like esophagous(difficulty swallowing), trachea or bronchus( difficulty breathing) or nerves like recurrent laryngeal nerve( horesness). ...Read moreSee 1 more doctor answer
Several theories: Most common belief is that aneurysms develop due to some inherent weakness in the artery's muscular layer due to an imbalance of collagen metabolism or genetic collagen abnormalities. The only independent risk of aneurysm growth is high blood pressure and smoking. ...Read moreSee 1 more doctor answer
Arteriosclerosis: Most arteriosclerotic aneurysms result in cystic medial necrosis of the aorta resulting in dilatation of the artery secodary to the internal pressure and weakness of the arterial wall. Any part of the aorta and its branches may be affected. Infections with bacteria, fungus, syphillis may also produce aneurysms in the aorta. ...Read moreSee 1 more doctor answer
Several things: About 5% of men over the age of 65 have abdominal aortic aneurysms. Risk factors include: increasing age, male sex, family history of aneurysm (may increase your risk 4-fold), hypertension, and history of smoking. Dissecting aneurysms can be caused by localized damage to to the artery from hypertension or trauma (deceleration or sheering-type injury) or catheter injury from an angiogram. ...Read moreSee 2 more doctor answers
AAA Prevention: Key ways to prevent AAA are to increase your general health. This includes stopping smoking, controlling diseases such as diabetes and hypertension, lowering your cholesterol and eating less salt. The best treatments for an AAA come from early diagnosis with regular check ups. If found early, they can be watched until something has to be done. ...Read moreSee 2 more doctor answers
Size: Abdominal aneurysms should be treated surgically if greater than or equal to 6 cm (sometimes 5.5 cm depending on the age and risks), if symptomatic or if it grows at a rate greater than 0.5 cm/ 6 months. The treatment is endovascular repair unless the anatomy is unfavorable (unusual). You should see a board certified vascular surgeon with endovascular experience. ...Read moreSee 1 more doctor answer
Less wall elastin : The aorta, the main artery that delivers blood from the chest to the belly, has a protein known as elastin in its wall. Smoking and COPD affect biochemistry destroying elastin, leading to weakening in the wall causing it to bulge out forming an aneurysm. Why most common in abdomen? Cause elastin layer is thickest in chest thins at renal arteries in abdomen - no surprise they often form there 1st! ...Read moreSee 1 more doctor answer
Good Question: The largest abdominal aneurysm I have operated on was 16 CM in diameter. It is unusual these days to find really large diameter aneuryms due to better screening & due to the number found incidentally when exams such as sonograms or ct scans are performed for other reasons. Increasing size correlates with increased rupture rates. ...Read moreSee 1 more doctor answer
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