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Doctor insights on: What Is The Most Accurate Test For Diagnosing Lupus

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I tested positive for lupus and negative for rheumatoid arthritis. How accurate are these tests?

I tested positive for lupus and negative for rheumatoid arthritis. How accurate are these tests?

Tests are accurate: If you have the right tests theses are quite accurate.You should discuss with your doctor who ordered the tests, because he knows your clinical history and will be able to explain the results to you.I can not answer without knowing the tests which were done. ...Read more

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How accurate is a skin biopsy for lupus? Can you have a false/ positive test result?

How accurate is a skin biopsy for lupus?  Can you have a false/ positive test result?

Lupus biopsy: Biopsy of lupus has a number of features that lead to diagnosis: a thickened basement membrane, vacuolar alteration of basal keratinocytes and superficial and deep inflammatory infiltrate. Lupus has a number of different forms in the skin and there are times when it is not easy to differentiate it from other types of skin inflammation. There are other tests to support diagnosis. ...Read more

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I got a positive lupus antibody test in june and was told I would need lifelong warfarin. Is this accurate?

I got a positive lupus antibody test in june and was told I would need lifelong warfarin. Is this accurate?

Not necessarily: If all you had was one positive lupus antibody test, then that is not an indication for treatment with warfarin. To make a diagnosis of antiphospholipid syndrome requires multiple positive tests over time in addition to a clinical finding such as a blood clot or miscarriages. http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/antiphospholipidsyndrome.asp. ...Read more

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How do antihistamines & other antinflammatories taken longterm affect accuracy of ESR,CRP, PTT tests when r/o lupus or other CTD's?

How do antihistamines & other antinflammatories taken longterm affect accuracy of ESR,CRP, PTT tests when r/o lupus or other CTD's?

Little or none: ESR (sed rate) and C-reactive protein are actually of little real use in the lupus workup, and the public and physicians set too much by them generally. PTT is used to look for the "lupus anticoagulants" that paradoxically cause thrombosis. The common meds that affect small molecules like histamine and prostaglandins don't impact production of the proteins involved in these tests, or lupus testing ...Read more

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Can you name all the tests for diagnosing lupus?

Can you name all the tests for diagnosing lupus?

TESTS FOR LUPUS: Cbc, urine and sed rare.Following test are important to diagnose lups 1ana titer is an important test, it is positive in 97%of patients with lupus.When threeor more typical features of lupus are present like, skin, joints, kidneys, lungs, heart, blood or nervous system, positive ANA will confirm it 2anti ds dna +iin half patients 3apls antibody+in 30% 4ro/ss-a and la/ss-b in skin lupus sm antibod 30-40%. ...Read more

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I have traces of leukocytes in urinalysis, otherwise all lupus test is normal. My doctor is in process of diagnosing me with lupus? Is it concerning?

See answer: Lupus, an autoimmune and chronic inflammatory disease that can affect the joints, skin, kidneys, lungs, nervous system and other organs. About 1.5 million americans have lupus, and 1/3 will develop kidney involvement characterized by protein in the urine and elevated blood creatinine levels. Trace leukocytes in the urine by itself and unassociated with urinary symptoms is most often normal finding. ...Read more

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What are tests for lupus?

What are tests for lupus?

See details.: Start with an ana. If that is positive check for dna, ena, ssa and ssb antibodies. If the ANA is negative, i strongly suggest that no other tests be done. ...Read more

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What does it mean if lupus test is negative?

Probably not lupus: Many people have symptoms suggestive of lupus but most turn out not to have the disease. The ANA and other blood tests are virtually always positive in patients with lupus. Negative tests mean you're not likely to have lupus. A bigger problem is false positive anas, in which case the teat is positive but the patient does not meed other diagnostic criteria to lupus. ...Read more

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What medical tests are done to diagnose lupus?

Many: Ana, double-stranded dna, smith antibody, rnp, ribosomal p, ssa, ssb, complement components.And cell bound complement activation products . These are some there are others it really depends on your evaluation and examination. ...Read more

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Could I have lupus? What tests are there for a diagnosis?

Lupus: There are quite a few tests that we use to diagnose lupus along with a physical exam. Some of these tests are: antinuclear antibodies (ana), anti-sm, anti-dsdna, and anti-rnp. Others might be used, but these are some of the main tests. ...Read more

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Do you have to be in a flare to test positive for Lupus?

Lupus : There are different tests for lupus. Diagnostic tests which can be positive even if you don't have a flare. Then there are test to determine disease activity which can be abnormal during flares. Mind you that a diagnosis of lupus depends on history, clinical exam in addition to lab. Best wishes ...Read more

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What can cause a positive lupus test without having lupus?

What can cause a positive lupus test without having lupus?

Sometimes drugs: Sometimes drugs can cause a positive lupus test, but the lupus test or ANA is designed to be overly sensitive so as not to miss cases, but the drawback is it can be positive in normal people. Your doctor should be able to handle this problem. ...Read more

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What does it mean if you have a possible positive lupus test?

What does it mean if you  have a possible positive lupus test?

Positive ANA: But a positive ANA does not mean you have lupus. A good history and physical as well as confirmatory blood work by your physician or a rheumatologist is the preferred course of action. There is no one "test" to diagnose lupus. ...Read more

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What exactly does it mean to have a possible positive lupus test?

Impossible to say: If is a positive ana, it may mean something or mean nothing. Anas are nonspecific and can be positive in numerous other diseases or even in normal people, you may want to consult a rheumatologist. ...Read more

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What are levels on a lupus test suppose to be? I don't know how to read it

What are levels on a lupus test suppose to be? I don't know how to read it

Not as important: Your disease activity is far more important. ANA levels are not worth much. Anti-ds-dna test most important, followed by complement levels. ...Read more

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Can you explain if it's possible to test negative for lupus but actually have it?

Very rarely: There is a big debate if there is sle without ana. A recent major reference on sle suggested that 98% of patients are ANA positive, leaving 2% without. However, the patients still need to have typical clinical manifestations to qualify for the diagnosis. ...Read more

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I have had a false positve syphills test since the age of 18 could i possibly have lupus?

Need further test: False positive RPR may suggest antibodies in the blood that is cross reacting with RPR test reagent. Common antibodies are antiphospholipid antibodies that gives false positive RPR. Lupus is diagnosed based on signs and symptoms PLUS presence of ANA antibodies in the blood. You can ask your MD to check for these antibodies by blood tests. ...Read more

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