Doctor insights on:
What Is The Life Expectancy Of People With Multiple Myeloma
Kahler disease is also known as Multiple myeloma. I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
Plasma cell cancer: Multiple myeloma is a cancer of plasma cells (pcs). Pcs are the specialized b lymphocytes that produce antibodies. When there is a cancer or one (mono-) clone (= monoclonal, m) pc population they can product m-proteins. Symptoms include crab - hypercalcemia, renal (kidney) insufficiency, anemia, bone disease; also infection and pain. More: http://www.Cancer.Net/cancer-types/multiple-myeloma. ...Read more
Labs, xrays: There are a series of blood and urine tests that will give the doctor a good idea if you have the disease. These are usually followed by x-rays looking for tell-tale signs of myeloma and a bone marrow test which would identify the cancer cells themselves. ...Read moreSee 1 more doctor answer
Much better now: With all the new targeted drugs for myeloma and several to come, patients live many more years. Some have said this cancer is now more like a chronic disease - still dangerous and needing treatment but it is characterized by longer periods of remission after treatment. Therefore a 65 or 75 year old person may have a normal life span with this disease now. ...Read moreSee 1 more doctor answer
Depends on heart: The light chain deposition disease is unlikely to affect survival. In fact a review of myeloma and kidney failure published last year demonstrated no change in outcome in myeloma patients with or without kidney failure. The biggest predictor of outcome is response to chemotherapy. Velcade (new chemo) has been a game changer. In addition, patients with cardiac involvement do very poorly. ...Read more
Years: This really varies depending most importantly on the chromosome abnormalities. Patients with this diagnosis are living longer, whereas previously many died within 3 years, most are living much longer. ...Read more
Disease of adults: Multiple myeloma is not a very common disease. It accounts for approximately 1% of all cancers multiple myeloma is a disease of older adults. The median age at diagnosis is 66 years; only 10 and 2 % of patients are younger than 50 and 40 years, respectively. It is not a disease of teenager. ...Read moreSee 1 more doctor answer
Does personalized medicine apply to diagnosis of typical conditions like multiple myeloma? What tests are needed?
Absolutely: Yes, absolutely . Molecular analysis with different methods are done to find some specific molecular markers/genes abnormality- this can be obtained from bone marrow and peripheral blood. This helps us in prognostication as well as in selecting medication. ...Read moreSee 1 more doctor answer
Multiple myeloma is a cancer of plasma cells (pcs). Pcs are the specialized b lymphocytes that produce antibodies. When there is a cancer or one (mono-) clone (= monoclonal, m) PC population they can product m-proteins. Symptoms include crab - hypercalcemia, renal (kidney) insufficiency, anemia, bone disease; also infection ...Read more
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