Doctor insights on:
What Is The Life Expectancy For A Person Who Has Severe Combined Immunodeficiency
Good with treatment: Without treatment, severe combined immunodeficiency is lethal in infancy. If treated with a bone marrow transplantation or similar immune reconstitution, before severe infections occur, life expectancy is the same as normal individuals. Adults with scid treated in childhood have their own children. Poor organ function as a result of infections leaving scars might limit life expectancy. ...Read more
That's when a person has a weakened immune system from whatever reason: drugs, infection, malnutrition, etc. While immunodeficiency, is when an arm of the immune system is weakened or absent, can be something primary (born with) or secondary (acquired later in life) ...Read more
Immunodeficiency: Scid is one of the life threatening immunodeficiencies that a child can be born with. Because of missing part of the immune system these children lack any ability to fight infection. It is imperative that they are identified within the first weeks of life so that treatment can be obtained. ...Read more
Definetely: Severe combined immunodeficiency (scid) are a group of genetic diseases that have in common their manifestation as a severe immune compromise, resulting in lack of defenses against infections. Genetic testing is available is specialized laboratories. A promising development is newborn screening for scid in some states: wi, ma, ny, ca. ...Read more
Houston patient: In the late 70's early 80's when not much could be done for scid, nasa designed the most sterile environment for a patient in houston, to avoid infections. Included was a space suit like. It worked relatively well. It was a 'bubble'. Social and psychological issues were significant however, and a matter of controversy. With bone marrow transplant advances, this extreme isolation is not needed. ...Read more
Forms of SCID: The original question asked about scid (severe combined immunedeficiency), not cvid (common variable immunodeficiency). There are several types of scid. Scid can be transmitted by both x-linked, and autosomal recessive patterns. Patients with scid have a defect in their immune system that makes them vulnerable to deadly infections. See an immunologist if you suspect scid. ...Read more
Depends: Scid screening should be done very early in life -- within the first few days. This test is clinically available and looks for, or the lack of, trec's -- which are parts of dna that should be present if immune system is developing properly. If scid screen is abnl and suggests scid the immunophenotyping will be done to confirm screen and further identify genetic defect. ...Read more
SCID treatment: Highly-trained pediatric immunologists in hospital settings are generally the doctors who treat scid. A good place for you to start learning about this disorder is to go to the website of the immune deficiency foundation: www. Primaryimmune. Org or to go to the jeffrey modell centers website: www. Info4pi. Org. Your local allergist/immunologist can also refer you to the nearest facility in your area. ...Read more
It really happened..: Scid (severe combined immunodef) is a life threatening condition that leaves a child with essentially no functioning immune system. They can die from infections. There was a child born in the 1970s whose father had connections at nasa. They were able to create a sterile environment for him (bubble) and a space suit for him to go "outside". He eventually died of complications. David vetter. ...Read more
Early history: In 1976 an early travolta movie (the boy in a plastic bubble) portrayed the life of a scid kid in a houston research facility. To avoid germs, the kid was kept in a sterilized room with limited access & bubble like clear plastic barriers that allowed his caretakers & family to see & interact with him. ...Read more
History, blood test:
Diagnosis is suspected when a child present with too many infections or failure to gain weight. It is confirmed by studying the number and function of t cells (special set of white blood cells). Genetic testing follows to classify the disease.
In some states (wi, ma, ca, ny) newborns are currently screened for scid. ...Read more
Not an easy answer: A person has two copies (or alleles) for each gene. One inherited from each parent. Dominant alleles are associated to clinical manifestations even when the other allele is normal. Two recessive alleles are needed to produce clinical manifestations. One recessive allele and one normal would result in a state called 'carrier', with no clinical symptoms. ...Read more
Early treatment: Early detection of scid will permit early treatment to avoid life threatening complications. A baby with scid is born with transient immunity from mom from the placenta. However, this material disappears leaving baby at risk for invasion infections. Scid babies will not develope antibodies to germs and fight them off. Early detection allows for treatment to avoid catastrophic illness. ...Read more
Yes, experimental: Over 30 patients with severe combined immunodeficiency (scid) have been treated with gene therapy. They have included Adenosine deaminase deficiency form and the x-linked form. Results have been highly promising and favorable compared to bone marrow transplantation. Long-term benefits and side effects are still been studied. ...Read more
Could someone who had Severe Combined Immunodeficiency as a child, who was treated with a bone marrow transplant aquire HIV from sexual activity?
Yes: There are too many different types of scid - severe combined immunodeficiency for there to be just one mutation. Scid is commonly referred to as "bubble boy" disease in the lay press. The most common type is linked to the x chromosome and causes a defect in t cells and natural killer cells. There are other autosomal recessive types of scid from different mutations. ...Read more
Are there any vitamins/foods that are proven (or recommended) to boost/strengthen immune system in a person with immunodeficiency?
It depends: Western medical doctors typically look for a deficiency (such as Vit D) or conditions which impacts the immune system. Therapy is then directed accordingly. In Washington State Naturopaths might have some other ideas and if you have a good Chinese Medicine Herbalist nearby check them out. Hopefully, there are biomarkers which can be followed to better assure effective therapy. ...Read more
Unlikely: Depending on the nature of the immune deficiency, you may be LESS likely to have an allergic reaction. It is possible, however. Yellow and red dyes have a propensity for causing allergy, probably because they're made from natural products. Blue dye has more of a propensity for causing a delayed rash (such as you might see with poison ivy). ...Read more
If my brother had a child with immunodeficiency at birth, should I get tested to see if my children will have it?
Depends on diagnosis: Chances of having children with a genetic condition depend on the specific genetic diagnosis. If the immunodeficient child was a boy, and the condition is x-linked, (gene defective is in chromsome x), then it is highly unlikely that the father has a similar gene defect. In all other scenarios most specific diagnosis is necessary for further counseling. ...Read more
What can you not do with immunodeficiency? The difference with a normal immune system and having immunodeficiency. Like everyday stuff?
Unclear question: There are many kinds of immunodeficiencies, so we need to know exactly what is the type and the cause of your immunodeficiency. It can be low level of immune cells (lymphocytes) like in HIV infections or it can be low level of immunoglobulins. You can do most anything and everything unless it is a total failure of the immune system which is extremely rare (it is called combined immunodeficiency...Of. ...Read more
From the knowledge of an educated professional, what are the key differences between immunosuppression and immunodeficiency? How can both be fixed?
Similar terms: These two two terms are frequently used somewhat interchangeably as they mean essentially the same thing: immune system is not working optimally. Immunosuppression is a bit more of a general term referring to the process of decreased immune function while immunodeficiency is more often used when there is a specific disease. Either way, fixing the underlying cause is needed. ...Read more
Evolution: It came from a simian precursor transmitted to humans by one of several mechanisms. This virus mutates continuously and the form to which it mutates which is best capable of surviving under the circumstances is the one which will be reproduced and multiply within infected cells. Unless of course you are a creationist. ...Read more
Sharing body fluids: Hiv is a sexually transmitted infection. It can also be spread by contact with infected blood, or from mother to child during pregnancy, childbirth or breast-feeding. It can take years before HIV weakens the immune system to the point that the patient has aids. There is no cure for hiv/aids, but there are medications that can dramatically slow the progression of the disease. ...Read more
Severe combined immunodeficiency or SCID is a genetic disorder. Patients have non functioning T and B cells - cells that are critical parts of immune system. Patients are susceptible to bacterial, fungal and viral infections as they lack defenses ...Read more
- Talk to a doctor online
- What is the life expectancy for someone who has an aortic valve regurgitation if not replaced?
- What is the average life expectancy of a person with cardiomyopathy?
- What is the life expectancy of a person with apert syndrome?
- Does anyone know the life expectancy of someone who was has tachycardia?
- Life expectancy for a person with elephantiasis
- Life expectancy for a person with cidp
- What is the life expectancy of a person with 20 percent pumping function of the heart?
- Severe pulmonary hypertension life expectancy
- Severe combined immunodeficiency