Doctor insights on:
What Is The Difference Between Tamoxifen And Femara
Different: Tamoxifen is a selective estrogen agonist/antagonist. It binds to estrogen receptors and depends on which organ it's on, it either exerts anti-estrogen or estrogen effects. Femara (letrozole) is an aromatase inhibitor. It inhibits enzymatic conversion of androgens to estrogen thereby lowering estrogen level. ...Read moreSee 1 more doctor answer
This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more
Both interfere with : Estrogen production and are used in treatment of breast cancer where the primary was er+. Side effects are similar, cost is much higher fro Letrozole (femara). It is newer. These are each used only in postmenopausal patients. Tamoxifen around for decades is used in premenopausal. ...Read moreSee 1 more doctor answer
Different companies: These drugs have different structures but act in the same way. Both are aromatase inhibitors. Arimidex (anastrozole) (generic name anastrazole) and Femara (generic name letrozole) may have different side effects in different women, as well as different costs. They can be used interchangeably. ...Read moreSee 2 more doctor answers
"cousin-drugs": Tamoxifen ("anti-estrogen") and aromatase inhibitors (ai) are both used for treating breast cancers that are estrogen-receptor +. Ai's are only suitable after menopause but may be slightly more effective; furthermore, they are not associated with any increased risk of uterine cancer like tamoxifen. ...Read moreSee 1 more doctor answer
Two different organs: Penectomy, or penile resection is used for controlling advanced ulcerating malignancy of the penis which is a rare Orchiectomy or castration is a form of surgery removing the testis to minimize the expression of male hormone in diseases affected by testosterone such as in advanced prostate cancer. The procedure is also employed in the presence of testicular cancer. ...Read more
Novedex vs Nolvadex (tamoxifen): Novedex xt is a product used to increase testosterone & muscle mass; it blocks the conversion of testosterone to estrogen, but apparently does not increase muscle mass.Nolvadex (tamoxifen) is used to treat breast cancer, but it reportedly is used by bodybuilders who use Anabolic steroids to prevent gynecomastia (enlarged breasts due to breast tissue rather than muscle. See following comment. ...Read more
Different action: Tamoxifen blocks the estrogen receptor, while Femara (letrozole) blocks the formation of estrogen. Estrogen levels are not lowered by tamoxifen, but they are lowered by femara (letrozole). Both cause hot flashes, bone loss, depression, memory problems and decreased libido. Tamoxifen increases blood clot and uterine cancer risk and causes vaginal discharge, while Femara (letrozole) causes more joint pain and vaginal dryness. ...Read moreSee 1 more doctor answer
Fertility/Eggs: Ovulation comes from the word "ova" or egg and refers to the monthly release of an egg. Fertility refers to the probability of becoming pregnant. If everything is working w/woman and partner physically, then they are likely fertile and an egg can be fertilized when cycle permits. If infertile, pregnancy cannot happen. Hope this helps. ...Read more
Antidepressants: They are pretty different on the neurotransmitters they affect (serotonin/norepinephrin), half life, molecular structure, side effects (like weight gain, paroxetine causes this more often; etc) and pharmacodynamics. They share some indications and uses (besides obviously as antidepressants) and both are relatively inexpensive. ...Read more
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