What is the difference between seminoma and nonseminoma cancer of the testicles - Doctor answers

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What are the symptoms of testicle cancer?

What are the symptoms of testicle cancer?

Painless mass.: Testicular cancer usually presents as a painless mass in the scrotum. Because there is often no pain, many unfortunately delay evaluation. As the mass enlarges, there may be discomfort or a sensation of fullness in the scrotum, seen in 30-40%. 10% experience acute pain. If the cancer spreads, symptoms of more advanced disease such as neck mass, back pain, bone pain, or cough may result. ...Read more

Dr. Barry Rosen
4,342 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is the difference between seminoma and nonseminoma cancer of the testicles?

What is the difference between seminoma and nonseminoma cancer of the testicles?

Different tumors: Over 90% of testis tumors are germ cell tumors which are seminoma, non-seminoma or mixed depending on the type of malignant cell. Classic seminoma is the most common testis tumor in adults. Almost all testis tumors are initially treated by surgical removal (orchiectomy). Then, based on the type of tumor and stage (aggressive characteristics, spread to lymph nodes) determines next treatment. ...Read more

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Post op seminoma, in r testicle. Pet scan done for suspecious nodes. Pet scan result shows negative for any abnormalility. This means no seminoma?

Post op seminoma, in r testicle. Pet scan done for suspecious nodes. Pet scan result shows negative for any abnormalility. This means no seminoma?

Surveillance: A negative pet scan means there is no accumulation of cancer cells large enough to be discernible by the pet scanner. There is a resolution limit of about 7mm in size to be seen, some are better now. I am not trying to scare you, but your doctor I'm sure will continue to caution you and continue surveillance for a period of time safe to say you are cancer-free. ...Read more

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Undecended right testicle and found seminoma, azoospermia in two samples with in 3 weeks. Left testicle normal in ultrasound scan. Am I sterile?

Undecended right testicle and found seminoma, azoospermia in two samples with in 3 weeks. Left testicle normal in ultrasound scan. Am I sterile?

Possibly: Sorry to hear about your recent diagnosis. Good news is that seminoma and testicular cancer in general almost always curable nowadays especially in early stages. Assuming your semen collections were correctly obtained and tested, complete absence of sperm (azoospermia) implies sterility. Would certainly recommend that this be evaluated further to determine cause especially in view of normal us. ...Read more

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Right testicle operated showed seminoma. Ct showed enlarged paraaortic lymph node. Does this means metastatis or due to surgery?

Right testicle operated showed seminoma. Ct showed enlarged paraaortic lymph node. Does this means metastatis or due to surgery?

Usually metastasis: Seminoma can occur in testes or the mediastinum as the primary tumor, it is classified as one of the germ cell tumors.
If there is regional paraaortic node histooogic involvement if usually is metastasis. Chemotherapy and/or radiation has very good cure rate even with metastases. At surgery they sample the regional nodes for involvement to determine best treatment for patient. ...Read more

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Operated undecended testicle showed tumor cells. Enlarged paraaortic lymph node in ct. But tumor markers normal. High alt (67). Is it still seminoma?

Operated undecended testicle showed tumor cells. Enlarged paraaortic lymph node in ct. But tumor markers normal. High alt (67). Is it still seminoma?

In situ?: The diagnosis of seminoma is made on examination of tissue by the pathologist; tumor markers and imaging are ancillary studies. An undescended testis often has premalignant cells lining the tubules; these are not yet cancer and if gone will not be troublesome. If you were told there was indeed an actual seminoma, that's a different story & you may require followup such as biopsy of the node. ...Read more

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Seminoma in post op intra abdominal r testicle (undcnd), l testicle normal in ultrasound scan, azoospermia in semen analysis. Can I father in future?

Seminoma in post op intra abdominal r testicle (undcnd), l testicle normal in ultrasound scan, azoospermia in semen analysis. Can I father in future?

More info: If u got chemo, it may take a few years to regenerate sperm. Also, seminoma is often treated with radiation but they likely shielded your left testis. I don't have enough information to predict how you're going to do. ...Read more

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What is the difference between a hernia and testicle cancer?

What is the difference between a hernia and testicle cancer?

Different Exam: An inguinal hernia is a hole in the groin muscles thru which a sac may protrude through, occasionally extending into the scrotal sac, next to the testicle. A testicular cancer presents as a growth within the testicle. These two abnormalities can be easily differentiated from one another by a careful physician examination. ...Read more

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In testicular cancer, how often is there not a palpable mass ON the testicle and the cancer is INSIDE the testicle. Difference between ON and IN common?

In testicular cancer, how often is there not a palpable mass ON the testicle and the cancer is INSIDE the testicle. Difference between ON and IN common?

Not meaningful diff.: This may be a semantic distinction more than a biological one. The cancer arises within the testicle, but may extend to the surface of that organ and bulge away from its surface. Thus, the tumor may FEEL to be on the testicle even though it has arisen from within it. Not all testicular cancer extends to the surface of the testicle. Palpation is clearly inferior to ultrasound examination here. ...Read more

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Does non seminoma testicular cancer made up of embryonic and yolk sac spread and where to?

Does non seminoma testicular cancer made up of embryonic and yolk sac spread and where to?

Can spread: Can spread to any part of the body including the brain ; need full body scan to eval. ...Read more

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I had a seminoma cancer. I got my semen's analysis done but there was no sperm (azospermia). Can you please tell me if I'm having azosperia because of cancer?

I had a seminoma cancer. I got my semen's analysis done but there was no sperm (azospermia). Can you please tell me if I'm having azosperia because of cancer?

Chemo?: Seminoma can be treated with chemo and radiation. If you had chemo, you may be infertile for a couple of years and sometimes permanently. Radiation can cause damage to the remaining testicle but it's usually left out of the radiation field. You need a male fertility specialist. ...Read more

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Is there any relation between azoospermia and seminoma cancer?

Is there any relation between azoospermia and seminoma cancer?

Low sperm counts: Are common in men with testis cancer, seminoma and non-seminoma. Reason is not clear. Some believe there is a developmental issue, undescended testis also at higher risk, others blame anesthetics. Truth be known, we do not know. ...Read more

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Seminoma tumour - testicular cancer, what to do?

Seminoma tumour - testicular cancer, what to do?

Orchiectomy: Lesion requires resection by orchiectomy with spermatic cord. Prior to this PET/CAT helpful since this tumor spreads quickly to para aortic nodes and may require chemo or RT depending on node size followed by chemotherapy. Cure rate high for this type of germ cell lesion. ...Read more

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What r the chances of cancer in child if father has seminoma?

What r the chances of cancer in child if father has seminoma?

Not high 1-3%: Approximately 1 to 3 percent of affected men have a family member with the disease.
Majority would be associated with some other factors- like undescended testes, infertility/subfertility, HIV infection, hypospadias, other condition like klinefelter's etc. ...Read more

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Have read the doubling time for nonseminoma testicular cancer is 10-30 days. What's the doubling time for seminoma?

Have read the doubling time for nonseminoma testicular cancer is 10-30 days. What's the doubling time for seminoma?

Can't say: You need to consult with an oncologist for this answer. There are many variables. Ask your family physician for a referral. ...Read more

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If one testicle is bigger than the other, is it likely to be cancer?

If one testicle is bigger than the other, is it likely to be cancer?

If growing bigger: If one testicle is growing bigger than the other one, after puberty, there could be a tumor in the growing testicle. A doctor's evaluation is needed. A ultrasound scan can be done. If a child developed one small and one bigger testicle, but they stayed the same size after puberty, they are likely ok. However, if the smaller one then grows to match the bigger one, a doctor can check for cancer. ...Read more

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What to do if I have had a slight pain in my right testicle for three weeks, could it be cancer?

What to do if I have had a slight pain in my right testicle for three weeks, could it be cancer?

See a doc: Testicular cancer is often painless but there's no way anyone can tell for sure without a physical exam and maybe an ultrasound. Please see your doc right away and best to you. ...Read more

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Does getting hit in the testicles lead to cancer?

Does getting hit in the testicles lead to cancer?

No: Ten percent of males diagnosed with testicular cancer give a history of recent trauma to the testicle. It is not thought that the trauma causes the cancer, but rather that it brings an existing tumor to the attention of the patient and physician. ...Read more

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Does teasing and denial increase the risk of testicle cancer?

Does teasing and denial increase the risk of testicle cancer?

No: Some couples like this. This actually causes the prostate and seminal vesicles to fill tremendously, giving some men more enjoyment when ejaculation finally takes place. The testes are unaffected. No one's shown any clearly increased risk in prostate cancer from abstinence, though the jury's still out on it being a risk for benign enlargement later. Seminal vesicle cancer almost never happens. ...Read more

Testicles (Definition)

The testicles are the two oval male gonads, or reproductive glands, located in the scrotum. The seminiferous tubules of the testis are the site of spermatogenesis and its leydig cells secrete testosterone. The term testicles is synonymous with testes or gonads. The singular form is ...Read more


Dr. Brad Goldenberg
32 Doctors shared insights

Seminoma (Definition)

A form of testicular cancer which is made by pathologic evaluation. It responds to removal of ...Read more