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Doctor insights on: What Is The Difference Between Osteosarcoma And Ewings Sarcoma

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What is the difference between osteosarcoma and ewing's sarcoma?

What is the difference between osteosarcoma and ewing's sarcoma?

Different cancers: These are two different types of cancer that occur in bones of young people. The locations in the body where they usually occur are different. Osteosarcoma is usually at knee or shoulder while ewing's is in thigh bone or pelvis. The chemotherapy used is different. Ewing's, unlike osteosarcoma, responds very well to radiation. Overall survival and metastasis rate is about same for both. ...Read more

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Dr. Janice Alexander
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Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


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Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?

Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?

Maintenance....: Is not typical in cancer rx, particularly not for solid tumors like ews or osteosarcoma. Yet, a prolonged period of surveillance is needed after completing rx. Surveillance is needed to address late effects of therapy and to monitor for disease recurrence. Maintenance has a prominent and essential role in all, and may become a part of rx for other cancers as we learn more of molecular pathogenesis. ...Read more

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Osteogenic sarcoma and osteosarcoma are the same tumors?

Osteogenic sarcoma and osteosarcoma are the same tumors?

Yes.: The two are synonyms. By definition, it is a sarcoma that produces malignant osteoid (immature bone) that is seen under the microsope. Osteogenic means "producing bone." other bone sarcomas, like ewing's, do not produce osteoid. Most arise in bone, but there are rare soft tissue osteosarcomas (or osteogenic sarcomas, depending on which term you prefer). ...Read more

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Is there any relation between ewings sarcoma and ovarian cancer?

Is there any relation between ewings sarcoma and ovarian cancer?

No: I know no syndrome in which the two run together, but if they did both occur at a young age in the same person, i would suspect one of the cancer family syndromes such as li fraumeni. If there was otherwise a strong family history, or the person wished to make a decision about parenthood, then a talk with a geneticist would be in order. ...Read more

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Could you tell me what happens if ewings sarcoma is not caught early?

Could you tell me what happens if ewings sarcoma is not caught early?

Early is hard....: Quantify. Implied in your question is a linear progression from localized to metastatic disease, but this may not be the case. There is research to suggest metastatic tumors are endowed with this ability from the start (the metastatic toolbox). Likewise, even apparently localized disease will shed tumor cells but not form metastases. Suggests different biology. Survival 75% (local) vs. <20% (mets). ...Read more

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I was wondering what are the side effects of ewings sarcoma?

Several : Patients typically present with pain in a bone. Most commonly the femur. Patients may also present with what is called a pathological fracture, a break in the bone caused by the cancer. This type of cancer commonly spreads to the lungs and if in an advanced stage, the patient may present with a cough or shortness of breath. Hope this helps. ...Read more

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How to treat ewings sarcoma?

How to treat ewings sarcoma?

Combination therapy: Chemotherapy is given to all patients and surgery and/or radiation therapy is used for local control. ...Read more

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How likely is ewings sarcoma coming back after five years?

Unlikely: Ewing sarcoma recurrence is most common within the first two years of diagnosis 90% of the time. After 5 years it is highly unlikely, but there are still reports of late recurrences in ewing sarcoma. ...Read more

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Is ewings sarcoma fatal?

Often is: Untreated, or treated only by a charlatan, it is 100% fatal. Generally it requires chemotherapy. The odds in early disease are quite good, and even with metastatic disease cures sometimes happen. ...Read more

Dr. Ilya Iofin
31 doctors shared insights

Ewing's Sarcoma (Definition)

Ewing's sarcoma is a type of cancer where this uncontrolled growth of cells found in bone. Symptoms can include pain, swelling, ...Read more


Dr. Ilya Iofin
723 doctors shared insights

Osteosarcoma (Definition)

Osteosarcoma is a type of bone cancer affecting children where the overgrowth of bone cell leads to bone pain, swelling, ...Read more