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Doctor insights on: What Is The Difference Between Osteosarcoma And Ewings Sarcoma

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What is the difference between osteosarcoma and ewing's sarcoma?

What is the difference between osteosarcoma and ewing's sarcoma?

Different cancers: These are two different types of cancer that occur in bones of young people. The locations in the body where they usually occur are different. Osteosarcoma is usually at knee or shoulder while ewing's is in thigh bone or pelvis. The chemotherapy used is different. Ewing's, unlike osteosarcoma, responds very well to radiation. Overall survival and metastasis rate is about same for both. ...Read more

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Dr. Ilya Iofin
32 doctors shared insights

Ewing's Sarcoma (Definition)

Ewing’s sarcoma, typically starts in the long bones, but can start in other tissues and muscles as a primitive neuroectodermal tumor. It is the third most common primary bone cancer occurring most frequently in children and teenagers. Treatment consists of neoadjuvant chemotherapy, with vincristine, doxorubicin, and cyclophosphamide following surgical resection. 5 ...Read more


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Osteogenic sarcoma and osteosarcoma are the same tumors?

Osteogenic sarcoma and osteosarcoma are the same tumors?

Yes.: The two are synonyms. By definition, it is a sarcoma that produces malignant osteoid (immature bone) that is seen under the microsope. Osteogenic means "producing bone." other bone sarcomas, like ewing's, do not produce osteoid. Most arise in bone, but there are rare soft tissue osteosarcomas (or osteogenic sarcomas, depending on which term you prefer). ...Read more

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Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?

Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?

Maintenance....: Is not typical in cancer rx, particularly not for solid tumors like ews or osteosarcoma. Yet, a prolonged period of surveillance is needed after completing rx. Surveillance is needed to address late effects of therapy and to monitor for disease recurrence. Maintenance has a prominent and essential role in all, and may become a part of rx for other cancers as we learn more of molecular pathogenesis. ...Read more

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Is ewings sarcoma fatal?

Often is: Untreated, or treated only by a charlatan, it is 100% fatal. Generally it requires chemotherapy. The odds in early disease are quite good, and even with metastatic disease cures sometimes happen. ...Read more

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How to treat ewings sarcoma?

How to treat ewings sarcoma?

Combination therapy: Chemotherapy is given to all patients and surgery and/or radiation therapy is used for local control. ...Read more

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How likely is ewings sarcoma coming back after five years?

Unlikely: Ewing sarcoma recurrence is most common within the first two years of diagnosis 90% of the time. After 5 years it is highly unlikely, but there are still reports of late recurrences in ewing sarcoma. ...Read more

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I was wondering what are the side effects of ewings sarcoma?

Several : Patients typically present with pain in a bone. Most commonly the femur. Patients may also present with what is called a pathological fracture, a break in the bone caused by the cancer. This type of cancer commonly spreads to the lungs and if in an advanced stage, the patient may present with a cough or shortness of breath. Hope this helps. ...Read more

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Can you tell me about ewings sarcoma of the bladder?

Can you tell me about ewings sarcoma of the bladder?

Very rare: Ewing's sarcoma is a very aggressive type of cancer, namely a primitive neuro-ectodermal tumor or type of sarcoma. Most commonly arising from bone. Single case reports of ewing's sarcoma of bladder have been reported. Survival is possible , if diagnosed early, surgically removed, patient treated with chemotherapy ; involved area treated with radiation therapy. ...Read more

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Could you tell me what happens if ewings sarcoma is not caught early?

Could you tell me what happens if ewings sarcoma is not caught early?

Early is hard....: Quantify. Implied in your question is a linear progression from localized to metastatic disease, but this may not be the case. There is research to suggest metastatic tumors are endowed with this ability from the start (the metastatic toolbox). Likewise, even apparently localized disease will shed tumor cells but not form metastases. Suggests different biology. Survival 75% (local) vs. <20% (mets). ...Read more

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Dr. Chad Levitt
2 doctors shared insights

Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


Dr. Ilya Iofin
724 doctors shared insights

Osteosarcoma (Definition)

Osteosaroma is a malignant neoplasm that arises ...Read more