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Doctor insights on: What Is The Difference Between Osteosarcoma And Ewings Sarcoma

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What is the difference between osteosarcoma and ewing's sarcoma?

What is the difference between osteosarcoma and ewing's sarcoma?

Different cancers: These are two different types of cancer that occur in bones of young people. The locations in the body where they usually occur are different. Osteosarcoma is usually at knee or shoulder while ewing's is in thigh bone or pelvis. The chemotherapy used is different. Ewing's, unlike osteosarcoma, responds very well to radiation. Overall survival and metastasis rate is about same for both. ...Read more

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Dr. Ilya Iofin
33 Doctors shared insights

Ewing's Sarcoma (Definition)

Ewing’s sarcoma, typically starts in the long bones, but can start in other tissues and muscles as a primitive neuroectodermal tumor. It is the third most common primary bone cancer occurring most frequently in children and teenagers. Treatment consists of neoadjuvant chemotherapy, with vincristine, doxorubicin, and cyclophosphamide following surgical resection. 5 ...Read more


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Osteogenic sarcoma and osteosarcoma are the same tumors?

Osteogenic sarcoma and osteosarcoma are the same tumors?

Yes.: The two are synonyms. By definition, it is a sarcoma that produces malignant osteoid (immature bone) that is seen under the microsope. Osteogenic means "producing bone." other bone sarcomas, like ewing's, do not produce osteoid. Most arise in bone, but there are rare soft tissue osteosarcomas (or osteogenic sarcomas, depending on which term you prefer). ...Read more

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Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?

Do all cancers have a maintenance program that goes with it after finishing chemotherapy? Specifically, cancers like ewing's sarcoma and osteosarcoma?

Maintenance....: Is not typical in cancer rx, particularly not for solid tumors like ews or osteosarcoma. Yet, a prolonged period of surveillance is needed after completing rx. Surveillance is needed to address late effects of therapy and to monitor for disease recurrence. Maintenance has a prominent and essential role in all, and may become a part of rx for other cancers as we learn more of molecular pathogenesis. ...Read more

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Is ewings sarcoma fatal?

Often is: Untreated, or treated only by a charlatan, it is 100% fatal. Generally it requires chemotherapy. The odds in early disease are quite good, and even with metastatic disease cures sometimes happen. ...Read more

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How to treat ewings sarcoma?

How to treat ewings sarcoma?

Combination therapy: Chemotherapy is given to all patients and surgery and/or radiation therapy is used for local control. ...Read more

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How likely is ewings sarcoma coming back after five years?

Unlikely: Ewing sarcoma recurrence is most common within the first two years of diagnosis 90% of the time. After 5 years it is highly unlikely, but there are still reports of late recurrences in ewing sarcoma. ...Read more

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I was wondering what are the side effects of ewings sarcoma?

I was wondering what are the side effects of ewings sarcoma?

Several: Patients typically present with pain in a bone. Most commonly the femur. Patients may also present with what is called a pathological fracture, a break in the bone caused by the cancer. This type of cancer commonly spreads to the lungs and if in an advanced stage, the patient may present with a cough or shortness of breath. Hope this helps. ...Read more

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Can you tell me about ewings sarcoma of the bladder?

Can you tell me about ewings sarcoma of the bladder?

Very rare: Ewing's sarcoma is a very aggressive type of cancer, namely a primitive neuro-ectodermal tumor or type of sarcoma. Most commonly arising from bone. Single case reports of ewing's sarcoma of bladder have been reported. Survival is possible, if diagnosed early, surgically removed, patient treated with chemotherapy ; involved area treated with radiation therapy. ...Read more

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Could you tell me what happens if ewings sarcoma is not caught early?

Could you tell me what happens if ewings sarcoma is not caught early?

Early is hard....: Quantify. Implied in your question is a linear progression from localized to metastatic disease, but this may not be the case. There is research to suggest metastatic tumors are endowed with this ability from the start (the metastatic toolbox). Likewise, even apparently localized disease will shed tumor cells but not form metastases. Suggests different biology. Survival 75% (local) vs. <20% (mets). ...Read more

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Has there been any known cases of ewings sarcoma in 3 year old female left humerus?

Has there been any known cases of ewings sarcoma in 3 year old female left humerus?

Yes, its not impossi: Ewing's sarcoma is a tumor of the young children, so there is not much unusual about this this case.
A pediatrician can help you to take care of it. But it requires quick response and serious action as it is a fast growing cancer. ...Read more

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Is there any relation between ewings sarcoma and ovarian cancer?

Is there any relation between ewings sarcoma and ovarian cancer?

No: I know no syndrome in which the two run together, but if they did both occur at a young age in the same person, I would suspect one of the cancer family syndromes such as li fraumeni. If there was otherwise a strong family history, or the person wished to make a decision about parenthood, then a talk with a geneticist would be in order. ...Read more

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What's the success rate for stem cell transplants in advanced stages of ewings sarcoma?

What's the success rate for stem cell transplants in advanced stages of ewings sarcoma?

Clinical trials...: The largest published study to date (one institution) showed no increase in survival over conventional chemotherapy. However, this question is currently being evaluated in a collaborative clinical trial between europe and the us. See:
http://www.Cancer.Gov/clinicaltrials/search/view? Version=healthprofessional&cdrid=68608. ...Read more

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What is the difference between osteosarcoma and osteochondroma?

What is the difference between osteosarcoma and osteochondroma?

Sarcs are malignant: Osteosarcoma is a cancer starting in bones, most commonly in children/young adults, while osteochondroma is a non-cancerous bony spur, most often occuring in teenagers. Osteochondromas usually need no treatment and are only followed, while osteosarcomas require agressive treatment, often including chemotherapy, radiation therapy and surgery; the prognosis has improved a great deal recently. ...Read more

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What is the difference between osteochondroma and osteosarcoma tumors?

Benign vs cancer: Osteochondromas are the most common form of non-cancerous bone tumors, usually look like they are growing on the bone surface, and do not spread beyond the affected bone. Osteogenic sarcomas are aggressive cancerous bone tumors that typically cause destruction of the involved bone as well as producing new bone in a haphazard fashion. ...Read more

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What is the difference between chondroblastic osteosarcoma and chondrosarcoma?

What is the difference between chondroblastic osteosarcoma and chondrosarcoma?

The first is a type: Of bone cancer with predominantly cartilage producing cells; while the other is a cancer of the cartilage tissue itself.
For specific concerns ask your oncologist.
Good luck. ...Read more

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Can other disorders develop from osteosarcoma?

Can other disorders develop from osteosarcoma?

Yes, from treatment: Osteosarcoma is an aggressive bone tumor treated with chemotherapy, radiation, and surgery. The intense treatment can cause later problems, including bone fractures and osteoporosis, neuropathy, loss of fertility, chronic pain, neuropathy, and changes in cognitive abilities. Secondary cancers can develop in the areas where radiation was received. ...Read more

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Can you please tell me how osteochondroma and osteosarcoma differ?

Both bone cancers: They are both bone cancers, but look somewhat differently under the microscope. Osteosarcoma is more common and generally presents in adolescents and young adults. Chondrosarcoma presents later usually. Treatment for osteosarcoma involves chemo and surgery whereas for chondrosarcoma is surgery and chemotherapy is controversial. ...Read more

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One of my friends just died today of osteosarcoma, is it possible that I could get that too?

Very unlikely: I am sorry for your loss. This type of cancer is not transmitted from person to person. Sometimes you can be at higher risk for osteosarcoma based on your family history, but most of the time it is just bad luck. The right type of cell acquires mutations at just the right time to eventually develop a cancer. Osteosarcoma is a rare disease. I am sorry your friend died of it. ...Read more

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How does radiation help with osteosarcoma?

It is not used in: Most cases (youths with extremity); not very responsive. I googled and found advocacy for its use. I have used it in flat bones of head and neck when there are poor alternatives. Os tends to metastasize: chem and surgery are main modalities. ...Read more

Dr. Jan Lei Iwata
2 Doctors shared insights

Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


Dr. Ilya Iofin
728 Doctors shared insights

Osteosarcoma (Definition)

A malignant neoplasm that arises ...Read more