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Doctor insights on: What Is The Difference Between Osteoporosis And Osteogenesis Imperfecta

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What is the difference between osteoporosis and osteogenesis imperfecta?

What is the difference between osteoporosis and osteogenesis imperfecta?

OI collagen disease: Osteogenesis imperfecta (oi) is a congenital disorder of collagen (important component of bone). Oi is present at birth, and leads to repeated fractures, starting in childhood. There is no consistent treatment to prevent fractures in oi. Osteoporosis refers to an acquired state of fragile bones, most commonly occurring in post-menopausal women. Many therapies can reduce osteoporosis fractures. ...Read more

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Dr. PHILIP WALLER
1,551 doctors shared insights

Osteoporosis (Definition)

Currently it is better to think of osteoporosis as a condition where the bone is weakened, and can be managed or treated rather than cured. This is usually performed by dietary modifications, ingestion of supplemental calcium, vitamin d and a class of agents notice the bisphosphonates. These are usually delivered via oral or intramuscular injection on a weekly or monthly ...Read more


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What can be done for people with osteogenesis imperfecta?

What can be done for people with osteogenesis imperfecta?

Medical follow up: Medical optimization and surgical stabilization of bones to optimize mobiligy. ...Read more

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Can you tell me about osteogenesis imperfecta inheritance patterns?

Can you tell me about osteogenesis imperfecta inheritance patterns?

Autosomal dominant: Osteogenesis impecta (OI) is transmitted in autosomal dominant fashion. Rare cases of OI, type II B & type II C, are transmitted in autosomal recessive inheritance. ...Read more

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Please tell me can I have osteogenesis imperfecta type 1? How to tell?

Please tell me can I have osteogenesis imperfecta type 1? How to tell?

Genetic testing : Osteogenesis I, can be evaluated and effectively ruled in or out by a geneticist. Physical exam finding, family history, and genetic testing can all be helpful. ...Read more

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What does the karyotype of a person who has osteogenesis imperfecta look like?

What does the karyotype of a person who has osteogenesis imperfecta look like?

Like everyone elses: it is a group of at least 8 genetic disorders. allthough it's genetic: 1) 35% didn't have it in their families (spontaneous mutation?) 2) it is dominant... one good gene one bad gene 3) it is the GENE... sub microscopic change in a handful of atoms in DNA.. NOT the chromosome. ...Read more

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Can osteogenesis imperfecta be curable?

Can osteogenesis imperfecta be curable?

No: osteogenesis imperfecta is not curable. There five types and they vary is severity. They can be treated with medication and allow patient to live with the disease. ...Read more

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Is there a cure for osteogenesis imperfecta?

Is there a cure for osteogenesis imperfecta?

A genetic disorder: Osteogenesis imperfecta is a group of disorders that cause bone fragility due to an error in the genetic code for type i collagen. All tissues that are composed of type i collagen are affected. There are many subtypes ranging in severity and associated comorbidities, but all include fragile bones. There is no cure yet. ...Read more

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Is osteogenesis imperfecta a curable disease?

Is osteogenesis imperfecta a curable disease?

No: It is an inherited connective tissue disease that produces "brittle bones" that results in non-traumatic fractures. It ranges from mild to lethal. There is no cure. Genetic counseling is indicated for the families. ...Read more

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Is osteogenesis imperfecta a chronic disease?

Yes: It exists from conception until death, so it qualifies as chronic.Some are symptomatic at birth and some not until much older. ...Read more

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Is osteogenesis imperfecta a form of dwarfism?

Yes : In it's more severe stated there is retardation of growth therefore dwarfism would be seen. ...Read more

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Dr. Linda DiMeglio
70 doctors shared insights

Brittle Bone Disease (Definition)

Osteogenesis imperfecta is a condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more


Dr. James Krick
95 doctors shared insights

Osteogenesis Imperfecta (Definition)

Osteogenesis imperfecta is a condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more