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What Is The Difference Between Norepinephrine And Epinephrine
Both: Are made in the adrenal glands of the body and are released in response to a need for increased energy. The fight or flight phenomenon. The biggest difference is that nor-epi causes more vasoconstriction of blood vessels where epi causes more increase in heart rate and cardiac output through contractility. ...Read moreSee 1 more doctor answer
1 extra carbon atom: Epinephrine has 1 more carbon & 2 more hydrogen atoms then norepinephrine. This small difference makes the molecules look different, so they interact differently with receptors, and have different effects. One example: norEpinephrine narrows blood vessels, increasing blood pressure; Epinephrine can narrow some arteries while dilating others, and can raise or lower blood pressure. ...Read moreSee 1 more doctor answer
Synthesis & Locale: Norepinephrine (ne) and Epinephrine (e) are both sympathomimetic catecholamines that are synthesized in the adrenal medulla and terminals of sympathetic neurons. Along the metabolic pathway, ne is synthesized first -- and when an enzyme adds a methyl group, you have epinephrine. Ne is the main catecholamine in peripheral tissue and sympathetic neurons. E is mostly made in the adrenal medulla. ...Read more
Drugs for Heart Test: Chemical stress tests are used to diagnose heart artery blockage in people who cannot treadmill exercise. Persantine is injected IV and dilates normal blood vessels more than abnormal ones causing an ischemic defect on a nuclear image. Dobutamine is injected IV and increases the heart rate and contractility with muscle fed by a blocked artery not responding as well as normal muscle. ...Read moreSee 1 more doctor answer
Antidepressants: They are pretty different on the neurotransmitters they affect (serotonin/norepinephrin), half life, molecular structure, side effects (like weight gain, paroxetine causes this more often; etc) and pharmacodynamics. They share some indications and uses (besides obviously as antidepressants) and both are relatively inexpensive. ...Read more
Stimulants: Methamphetamine (desoxyn) belongs to the amphetamine group of stimulants. It comes in 2 forms; dextro- form which is the psychostimulant, & the levo-form which is an over-the-counter nasal decongestant. Meth is highly addictive. Methylphenidate (ritalin) belong to the non-amphetamine group of stimulants. Due to ritalin's short elimination half-life, rebound symptoms are more common. ...Read more
Differences: These two medicines share similarities, but they have different chemical structures, leading to different actions on the nervous system. Fluoxetine almost exclusively acts on the neurotransmitter serotonin, while duloxetine has a mixed action on both serotonin and norepinephrine. This difference will sometimes result in a person doing better with one medicine versus the other. ...Read more
See below: •noradrenaline is the main neurotransmitter of the sympathetic nerves in the cardiovascular system. •adrenaline is the main hormone secreted by the adrenal medulla. •the sympathetic noradrenergic system plays major roles in tonic and reflexive changes in cardiovascular tone. •adrenaline is a major determinant of responses to metabolic or global challenges to homeostasis. ...Read more
Polarity: Hi. Phospholipids (PLs) are polar, amphipathic molecules: part of the molecule loves a water environment and the other part loves an oily (non-water) environment. PLs are the main lipid component of cell membranes and the coats of lipoproteins. Triglycerides (fats, like butter, oils, lard) are hydrophobic and not soluble in water. PLs help create a hydrophobic environment for non-water soluble lip ...Read more
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