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Doctor insights on: What Is The Difference Between Norepinephrine And Epinephrine

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Dr. Mitchell Zeitler
Board Certified, Anesthesiology
34 years in practice
352K people helped
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What is the difference between norepinephrine and epinephrine?

Dr. Mitchell Zeitler
Board Certified, Anesthesiology
34 years in practice
352K people helped
What is the difference between norepinephrine and epinephrine?

Receptors: Epinephrine binds strongly to beta receptors which causes the heart rate to increase and heart to contract more forcefully. It also has Alpha receptor activity which causes blood vessels to contract which increases the blood pressure but norEpinephrine has a stronger effect on Alpha so it is used to increase blood pressure. Epinephrine would used in cases of heart failure to increase output. ...Read more

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Dr. Peter Kurzweil
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45 years in practice
16M people helped
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Dr. Peter Kurzweil
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Dr. Ravi Chand
740 doctors shared insights

Norepinephrine (Definition)

Norepinephrine is an inotrope which is a kind of heart ...Read more


Dr. Mark Gujer
Board Certified, Anesthesiology
21 years in practice
852K people helped
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2
What is the difference between epinephrine and norepinephrine?

Dr. Mark Gujer
Board Certified, Anesthesiology
21 years in practice
852K people helped

Both: Are made in the adrenal glands of the body and are released in response to a need for increased energy. The fight or flight phenomenon. The biggest difference is that nor-epi causes more vasoconstriction of blood vessels where epi causes more increase in heart rate and cardiac output through contractility. ...Read more

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Dr. Peter Kurzweil
Board Certified
45 years in practice
16M people helped
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Dr. Peter Kurzweil
Board Certified
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Dr. Pamela Pappas
Board Certified, Psychiatry
37 years in practice
135M people helped
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3
Is there a difference between epinephrine and norepinephrine?

Dr. Pamela Pappas
Board Certified, Psychiatry
37 years in practice
135M people helped
Is there a difference between epinephrine and norepinephrine?

Synthesis & Locale: Norepinephrine (ne) and Epinephrine (e) are both sympathomimetic catecholamines that are synthesized in the adrenal medulla and terminals of sympathetic neurons. Along the metabolic pathway, ne is synthesized first -- and when an enzyme adds a methyl group, you have epinephrine. Ne is the main catecholamine in peripheral tissue and sympathetic neurons. E is mostly made in the adrenal medulla. ...Read more

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Dr. Llewelyn Williams
Board Certified, Anesthesiology
24 years in practice
31K people helped
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4
What happens if I had infinite energy. could it be a problem with norepinephrine and epinephrine?

Dr. Llewelyn Williams
Board Certified, Anesthesiology
24 years in practice
31K people helped
What happens if I had infinite energy. could it be a problem with norepinephrine and epinephrine?

May be thyroid: If you are not takin stimulants like caffeine or energy drinks and have a yearly physical with normal blood work then be thankful. It could be hyper active thyroid but you would also have weight loss with anxiety and difficulty sleep along with other symptom. If not seeing a physician for more than a year it may be time ...Read more

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Dr. Peter Kurzweil
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Dr. Oscar Novick
Board Certified, Pediatrics
53 years in practice
54M people helped
5

5
Smoking causes epinephrine release in the body, does it cause a release of norepinephrine too?

Dr. Oscar Novick
Board Certified, Pediatrics
53 years in practice
54M people helped
Smoking causes epinephrine release in the body, does it cause a release of norepinephrine too?

Smoking: Yes it can also cause the release of norepheneprine. ...Read more

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Dr. Charles Gordon
Board Certified, Adolescent Medicine
587K people helped
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My 11 year old son has highly elevated levels of norepinephrine and epinephrine. How can we help him?

Dr. Charles Gordon
Board Certified, Adolescent Medicine
587K people helped

Elevated epi and nor: You did mention any symptoms yet. There is a condition called pheochromocytoma (tumor of the adrenal gland) which he may have. Speak to his doc and since you 're in North Carolina now the place for him to be seen is Mr Duke's Place (Duke Children's Hospital). Go!! ...Read more

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Dr. Pedro Cabrera
Board Certified, Anesthesiology
244K people helped
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Can you tell me the two systems which secrete epinephrine and norepinephrine.?

Dr. Pedro Cabrera
Board Certified, Anesthesiology
244K people helped

Epinephrine and NE: The adrenals and the CNS

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Dr. William Jenkins
Board Certified, Anesthesiology
1M people helped
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Does any hormone or chemical have opposing effects to epinephrine and norepinephrine?

Dr. William Jenkins
Board Certified, Anesthesiology
1M people helped
Does any hormone or chemical have opposing effects to epinephrine and norepinephrine?

Probably the best: Example is acetylcholine, but you can't take it as a medication ...Read more

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Dr. Rodney Del Valle
Board Certified, Anesthesiology
31 years in practice
1M people helped
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9
946 norepinephrine, below 10 epinephrine, 27 metanephrine should I be concerned of these results.

Dr. Rodney Del Valle
Board Certified, Anesthesiology
31 years in practice
1M people helped

Assuming: This results are serum levels. Norepinephrine level in pg/ml of 946 are high for an adult patient. Epi level appear normal. Serum levels without any more info like 24 hrs urine collection and ct results plus symptoms do not mean a lot. Patient should calm and supine for 30 minutes before collection. Assuming they are working out you for pheocromocytoma. Talk to your doctor with results. ...Read more

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Dr. Pamela Pappas
Board Certified, Psychiatry
37 years in practice
135M people helped
10

10
Sine seratonin depletes other nerotransmitters like dopamine, norepinephrine, and epinephrine...By "deplete" does it mean a permanent thing?

Dr. Pamela Pappas
Board Certified, Psychiatry
37 years in practice
135M people helped
Sine seratonin depletes other nerotransmitters like dopamine, norepinephrine, and epinephrine...By "deplete" does it mean a permanent thing?

Not correct: Serotonin does not deplete other neurotransmitters, but there is a balance especially between Dopamine and serotonin. This balance is dynamic and constantly re-establishing itself. Unless there is damage to neurons (which there can be when abusing certain drugs) neurotransmitter changes would not be permanent. ...Read more

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Dr. Ravi Chand
64 doctors shared insights

Levophed (Definition)

Levophed is an inotrope which is a kind of heart ...Read more


Dr. Mohammad Shahzad
967 doctors shared insights

Epinephrine (Definition)

Epinephrine is a rhythm control agent which is a ...Read more


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Dr. Peter Kurzweil
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