Top
10
Doctor insights on: What Is The Difference Between Neurofibromatosis1 And Neurofibromatosis 2

Share
1

1
Help! Is it possible to have a lot of cafe au lait spots and not have neurofibromatosis?

Help! Is it possible to have a lot of cafe au lait spots and not have neurofibromatosis?

Possible: NIH diagnostic criteria for NF1 with two or more of following features:1)6 or more café-au-lait macules over 5 mm in diameter prepubertal individuals over 15 mm in greatest diameter in postpubertal..2) 2or more neurofibromas or one plexiform neurofibroma.3)Freckling in armpit or groin areas4)Optic glioma (optic nerve tumor)5) > 2 Lisch nodules(iris of eye)6)typical bone lesions 7)1deg relative nf1 ...Read more

See 1 more doctor answer
Dr. Gerald Mandell
160 doctors shared insights

Neurofibromatosis (Definition)

Neurofibromatosis is a genetic condition characterized by caf_ au lait spots, which are pigmented patches of skin, and benign ...Read more


2

2
What is the difference between neurofibromatosis1 and neurofibromatosis 2?

Etiology: Nf 1 also called von recklinhausen, caused by single gene disorder on chromosome 17 and causes non cancerous lumps. Nf 2 also called central neurofibromatosis caused by mutation of merlin in chromosome 22q12. 10% of all nf and causes bilateral acoustic tumors. ...Read more

See 2 more doctor answers
3

3
Is there any difference between neurofibromatosis 1 and neurofibromatosis 2?

Etiology: Neurofibromatosis (nf) 1 is called von recklinghouse, caused by single gene disorder on chromosome 17, causes non-cancerous lumps. Nf 2 also called central nf is a mutation of merlin in chromosome 22q12, 10% of all nf and causes bilateral acoustic tumors. ...Read more

See 2 more doctor answers
4

4
What is the infant mortality rate from neurofibromatosis 1?

Poor prognosis: Congenital generalized (disseminated) neurofibromatosis (detected prenatally) is associated with poor prognosis, with mortality rate of 92%. ...Read more

5

5
What is the infant mortality rate from neurofibromatosis 1?

What is the infant mortality rate from neurofibromatosis 1?

Poor prognosis: Congenital generalized (disseminated) neurofibromatosis (detected prenatally) is associated with poor prognosis, with mortality rate of 92%. ...Read more

6

6
Please help! what is the infant mortality rate of neurofibromatosis 1?

Depends amt. of nf: Congenital generalized (disseminated) neurofibromatosis (detected prenatally) is associated with a poor prognosis, with a mortality rate of 92%. Survival rates for patients detected before and after birth were 28% and 62%.However most cases of nf are focal and not disseminated without evidence of increased infantile mortality rate. In people with nf the overall decrease in life span is about 8 yrs. ...Read more

7

7
Would a diagnosis of neurofibromatosis 1 be a disqualifier for being a living kidney donor?

Would a diagnosis of neurofibromatosis 1 be a disqualifier for being a living kidney donor?

No: As you are not transmitting genetic disease as in sperm donor , if you are healthy and your own health is not at risk , kidney donation is permissible ...Read more

See 1 more doctor answer
8

8
Is it normal for optic nerve tumors to cause impairment in vision (neurofibromatosis 1)?

Is it normal for optic nerve tumors to cause impairment in vision (neurofibromatosis 1)?

Usually: The symptoms are caused by tumor growing and pressing on the optic nerve and nearby structures. Symptoms may include: •involuntary eyeball movement, eyes bulging outward, squinting, loss of vision in one or both eyes leading to eventual blindness this may be losso of peripheral vision or more general loss. ...Read more

See 1 more doctor answer
9

9
Is there any difference between neurofibromatosis and elephant man's disese?

Unknown: Despite multiple attempts at diagnosis, there is no sure diagnosis of the disease joseph merrick suffered from. It was thought for many years he had nf, though he may have had proteus disease. There are numerous conditions that can cause extreme deformities that look similar. ...Read more

See 1 more doctor answer
10

10
My son has neurofibromatosis type 1 and he is only 2 years old. What symptoms can I expect?

My son has neurofibromatosis type 1 and he is only 2 years old. What symptoms can I expect?

NF 1 is caused by : mutations of the NF gene, 17q11.2. Clinical course varies widely depending largely on location & size of brain, skin, eye & other tumors. Initial evaluations by a geneticist, ped. neurologist, ped. ophthalmologist, developmental/behavioral pediatrician. & Early Intervention, http://www.dds.ca.gov/EarlyStart/home.cfm., guide management. Learning Disabilities & ADHD are common. See www.ctf.org. ...Read more