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Doctor insights on: What Is The Difference Between Humira And Etanercept

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What is the difference in mechanism or humira and enbrel (etanercept)?

What is the difference in mechanism or humira and enbrel (etanercept)?

None: There both basically work by the same mechanism which is inhibition of tnp. ...Read more

Dr. Robert Lowe
121 doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


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Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! both should be tried only after Methotrexate therapy has failed! ...Read more

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Are there other alternatives to enbrel (etanercept) and humira?

Are there other alternatives to enbrel (etanercept) and humira?

Yes: It depends on the disease being treated. For psoriasis (my field is dermatology), there is infliximab (remicade), ustekinemab (stelara), alefacept (amevive) - not used much now and golimumab (simponi) - not used much either. ...Read more

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I was on humira and felt terrible, is enbrel (etanercept) any better?

It's different: Different people react differently to different medications. It is possible that you will have the same trouble with Enbrel (etanercept) but it's also possible that you will have no trouble with enbrel (etanercept). The only way to know for certain is to try it. ...Read more

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With other tnf inhibitors such as humira and enbrel (etanercept) are there?

See below: Cimzia (certolizumab pegol), simponi (golimumab), and Remicade (infliximab) are the other tnf Alpha inhibitors available in the United States. ...Read more

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What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more

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Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more

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Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more

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Dr. Robert Lowe
140 doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more


Dr. Robert Lowe
169 doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more