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Doctor insights on: What Is The Difference Between Celiac And Lupus

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Can positive dsdna be something other than lupus--like celiacs?

Can positive dsdna be something other than lupus--like celiacs?

Autoantibody: Anti ds dna is an autoantibody that can be positive in a variety of disorders and by itself does not make a diagnosis. In the absence of symptom description, one cannot make a diagnosis based on a blood test. ...Read more

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Dr. John Chiu
603 doctors shared insights

Celiac Disease (Definition)

In celiac disease, the body reacts to gluten (in wheat and gluten-like proteins in rye and barley) resulting in damage to the small intestine. This limits the intestine's ability to absorb some nutrients. Typically, people with celiac disease have loose stools, bloating, abdominal pain or discomfort, weight loss, poor weight gain ...Read more


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I was told I have elevated ANA and that I have lupus. I then was diagnosed with celiac. Does celiac cause elevated ANA?

I was told I have elevated ANA and that I have lupus.  I then was diagnosed with celiac. Does celiac cause elevated ANA?

Autoantibodies: No. There are 4 types of antibodies. The type responsible for Celiac disease is an IgA whereas the ANA is an IgG. Of note, normal people can have elevated ANA. A diagnosis of lupus requires other confirmatory tests. ...Read more

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I have lupus, painful interstitial cystitis, and lots of GI issues. Is it worth trying gluten free diet for a while though my celiac test was negative?

I have lupus, painful interstitial cystitis, and lots of GI issues. Is it worth trying gluten free diet for a while though my celiac test was negative?

Absolutely: Also consider casein free (avoid cow dairy). Must go gluten free for at least 3-6 months for an adequate trial. Casein can cross react and look like gluten. Celiac testing is not accurate. Consider probiotics such as kombucha and kefir (water or goats milk). Can make both yourself at home. ...Read more

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Pos ana-- lupus symptoms but more celiac with bloating, blister like skin rash.. What should I do? Tests?

What has been done: To answer your physician needs to know what has been done. The questions you ask can be clarified by your laboratory studies. Because a positive ANA is a beginning and as you ask more tests are necessary. You and your physician can best approach this by looking at what test you have now and what test you need later. ...Read more

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Smoke/alco free 15 months. New labs show high ldh + lipase; borderline low amylase + globulin. Already ruled out ibd, celiac, mono, hep, hiv, tb, lupus, ra. July ct=normal liver/kidneys/panc. Cancer?

Smoke/alco free 15 months. New labs show high ldh + lipase; borderline low amylase + globulin. Already ruled out ibd, celiac, mono, hep, hiv, tb, lupus, ra. July ct=normal liver/kidneys/panc. Cancer?

MRCP: Looks like you have pancreatitis, but if you have not had alcohol, need mrcp to see if there any pancreatic duct abnormalities. Need more info, were you drinking before and did you have multiple pancreatits before? Mrcp followed by eus would help. Ercp may be needed once acute episode is resolved, or if you find any stricture in the duct. ...Read more

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What is the difference between discoid lupus and discoid ecxema?

What is the difference between discoid lupus and discoid ecxema?

Distinct illnesses: Discoid lupus is a chronic, tough-to-manage illness that will require protection from light and some tricky medication decisions. Discoid / nummumlar eczema is usually trivial and easily managed with some topical creams. I'm hoping it's the latter. Best wishes. ...Read more

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What is the difference between drug-induced lupus & systemic lupus? 

Very different : There are differences - especially less kidney involvement, different serology to name some things . It mostly resolves after stopping the drug involved. ...Read more

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What is the difference between the effects of MS and lupus on the nervous system?

What is the difference between the effects of MS and lupus on the nervous system?

Deceptive likeness: Both lupus and ms are autoimmune disorders and both affect the central nervous system. Both causes apparently random, sudden and often bizarre symptoms. Treatments for ms long-term have now been primarily interferon-based. No such widely accepted treatment exists for lupus. Steroids are often helpful in both conditions in short term. Diagnostic tests can separate the 2 conditions often. ...Read more